188 related articles for article (PubMed ID: 24385586)
1. In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene.
Dunn GP; Cheung HW; Agarwalla PK; Thomas S; Zektser Y; Karst AM; Boehm JS; Weir BA; Berlin AM; Zou L; Getz G; Liu JF; Hirsch M; Vazquez F; Root DE; Beroukhim R; Drapkin R; Hahn WC
Proc Natl Acad Sci U S A; 2014 Jan; 111(3):1102-7. PubMed ID: 24385586
[TBL] [Abstract][Full Text] [Related]
2. Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression.
Duckworth C; Zhang L; Carroll SL; Ethier SP; Cheung HW
Oncogene; 2016 Aug; 35(31):4036-47. PubMed ID: 26657155
[TBL] [Abstract][Full Text] [Related]
3. The Tyrosine Kinase Adaptor Protein FRS2 Is Oncogenic and Amplified in High-Grade Serous Ovarian Cancer.
Luo LY; Kim E; Cheung HW; Weir BA; Dunn GP; Shen RR; Hahn WC
Mol Cancer Res; 2015 Mar; 13(3):502-9. PubMed ID: 25368431
[TBL] [Abstract][Full Text] [Related]
4. Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition.
Davis SJ; Sheppard KE; Anglesio MS; George J; Traficante N; Fereday S; Intermaggio MP; Menon U; Gentry-Maharaj A; Lubinski J; Gronwald J; Pearce CL; Pike MC; Wu A; Kommoss S; Pfisterer J; du Bois A; Hilpert F; Ramus SJ; Bowtell DD; Huntsman DG; Pearson RB; Simpson KJ; Campbell IG; Gorringe KL
Mol Cancer Ther; 2015 Jun; 14(6):1495-503. PubMed ID: 25852062
[TBL] [Abstract][Full Text] [Related]
5. Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells.
Wang Y; Sheng Q; Spillman MA; Behbakht K; Gu H
Oncogene; 2012 May; 31(20):2512-20. PubMed ID: 21996746
[TBL] [Abstract][Full Text] [Related]
6. Gab2 promotes cancer stem cell like properties and metastatic growth of ovarian cancer via downregulation of miR-200c.
Fang Z; Li T; Chen W; Wu D; Qin Y; Liu M; Wu G; He L; Li H; Gu H
Exp Cell Res; 2019 Sep; 382(1):111462. PubMed ID: 31194976
[TBL] [Abstract][Full Text] [Related]
7. Focal amplification and oncogene dependency of GAB2 in breast cancer.
Bocanegra M; Bergamaschi A; Kim YH; Miller MA; Rajput AB; Kao J; Langerød A; Han W; Noh DY; Jeffrey SS; Huntsman DG; Børresen-Dale AL; Pollack JR
Oncogene; 2010 Feb; 29(5):774-9. PubMed ID: 19881546
[TBL] [Abstract][Full Text] [Related]
8. Functional analysis of genes in regions commonly amplified in high-grade serous and endometrioid ovarian cancer.
Davis SJ; Sheppard KE; Pearson RB; Campbell IG; Gorringe KL; Simpson KJ
Clin Cancer Res; 2013 Mar; 19(6):1411-21. PubMed ID: 23362323
[TBL] [Abstract][Full Text] [Related]
9. Gab2 Ablation Reverses the Stemness of HER2-Overexpressing Breast Cancer Cells.
Zhang P; Chen Y; Gong M; Zhuang Z; Wang Y; Mu L; Wang T; Pan J; Liu Y; Xu J; Liang R; Yuan Y
Cell Physiol Biochem; 2018; 50(1):52-65. PubMed ID: 30326469
[TBL] [Abstract][Full Text] [Related]
10. Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit.
Sun J; Pedersen M; Rönnstrand L
J Biol Chem; 2008 Oct; 283(41):27444-27451. PubMed ID: 18697750
[TBL] [Abstract][Full Text] [Related]
11. Amplification of 11q13 in ovarian carcinoma.
Brown LA; Kalloger SE; Miller MA; Shih IeM; McKinney SE; Santos JL; Swenerton K; Spellman PT; Gray J; Gilks CB; Huntsman DG
Genes Chromosomes Cancer; 2008 Jun; 47(6):481-9. PubMed ID: 18314909
[TBL] [Abstract][Full Text] [Related]
12. Grb2-associated binder 2 silencing impairs growth and migration of H1975 cells via modulation of PI3K-Akt signaling.
Wang WJ; Mou K; Wu XF; Zhang JZ; Ren G; Qi JD; Xu YF; Yao X
Int J Clin Exp Pathol; 2015; 8(9):10575-84. PubMed ID: 26617767
[TBL] [Abstract][Full Text] [Related]
13. The miR-218/GAB2 axis regulates proliferation, invasion and EMT via the PI3K/AKT/GSK-3β pathway in prostate cancer.
Tian J; Zhang H; Mu L; Wang M; Li X; Zhang X; Xie E; Ma M; Wu D; Du Y
Exp Cell Res; 2020 Sep; 394(1):112128. PubMed ID: 32522441
[TBL] [Abstract][Full Text] [Related]
14. Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.
Nyga R; Pecquet C; Harir N; Gu H; Dhennin-Duthille I; Régnier A; Gouilleux-Gruart V; Lassoued K; Gouilleux F
Biochem J; 2005 Aug; 390(Pt 1):359-66. PubMed ID: 15833084
[TBL] [Abstract][Full Text] [Related]
15. Oncogenic Signaling Adaptor Proteins.
Luo LY; Hahn WC
J Genet Genomics; 2015 Oct; 42(10):521-529. PubMed ID: 26554907
[TBL] [Abstract][Full Text] [Related]
16. Synergistic effects of SHP2 and PI3K pathway inhibitors in GAB2-overexpressing ovarian cancer.
Sun B; Jensen NR; Chung D; Yang M; LaRue AC; Cheung HW; Wang Q
Am J Cancer Res; 2019; 9(1):145-159. PubMed ID: 30755818
[TBL] [Abstract][Full Text] [Related]
17. Elevated Gab2 induces tumor growth and angiogenesis in colorectal cancer through upregulating VEGF levels.
Ding C; Luo J; Fan X; Li L; Li S; Wen K; Feng J; Wu G
J Exp Clin Cancer Res; 2017 Apr; 36(1):56. PubMed ID: 28420432
[TBL] [Abstract][Full Text] [Related]
18. Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer.
Ding C; Luo J; Li L; Li S; Yang L; Pan H; Liu Q; Qin H; Chen C; Feng J
J Exp Clin Cancer Res; 2016 Jan; 35():5. PubMed ID: 26754532
[TBL] [Abstract][Full Text] [Related]
19. LncRNA snaR upregulates GRB2-associated binding protein 2 and promotes proliferation of ovarian carcinoma cells.
Huang Y; Hu Y; Jin Z; Shen Z
Biochem Biophys Res Commun; 2018 Sep; 503(3):2028-2032. PubMed ID: 30093110
[TBL] [Abstract][Full Text] [Related]
20. Critical role for Gab2 in transformation by BCR/ABL.
Sattler M; Mohi MG; Pride YB; Quinnan LR; Malouf NA; Podar K; Gesbert F; Iwasaki H; Li S; Van Etten RA; Gu H; Griffin JD; Neel BG
Cancer Cell; 2002 Jun; 1(5):479-92. PubMed ID: 12124177
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]