These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

89 related articles for article (PubMed ID: 24388981)

  • 1. Polyglutamine expansion disturbs the endoplasmic reticulum formation, leading to caspase-7 activation through Bax.
    Ueda M; Li S; Itoh M; Hayakawa-Yano Y; Wang MX; Hayakawa M; Hasebe-Matsubara R; Ohta K; Ohta E; Mizuno A; Hida Y; Matsumoto M; Chen H; Nakagawa T
    Biochem Biophys Res Commun; 2014 Jan; 443(4):1232-8. PubMed ID: 24388981
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expanded polyglutamine embedded in the endoplasmic reticulum causes membrane distortion and coincides with Bax insertion.
    Ueda M; Li S; Itoh M; Wang MX; Hayakawa M; Islam S; Tana ; Nakagawa K; Chen H; Nakagawa T
    Biochem Biophys Res Commun; 2016 May; 474(2):259-263. PubMed ID: 27079237
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GRP78 counteracts cell death and protein aggregation caused by mutant huntingtin proteins.
    Jiang Y; Lv H; Liao M; Xu X; Huang S; Tan H; Peng T; Zhang Y; Li H
    Neurosci Lett; 2012 May; 516(2):182-7. PubMed ID: 22490889
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins.
    Reijonen S; Putkonen N; Nørremølle A; Lindholm D; Korhonen L
    Exp Cell Res; 2008 Mar; 314(5):950-60. PubMed ID: 18255062
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.
    Lee H; Noh JY; Oh Y; Kim Y; Chang JW; Chung CW; Lee ST; Kim M; Ryu H; Jung YK
    Hum Mol Genet; 2012 Jan; 21(1):101-14. PubMed ID: 21954231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release.
    Jana NR; Zemskov EA; Wang Gh ; Nukina N
    Hum Mol Genet; 2001 May; 10(10):1049-59. PubMed ID: 11331615
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy.
    Atwal RS; Truant R
    Autophagy; 2008 Jan; 4(1):91-3. PubMed ID: 17986868
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis.
    Sang TK; Li C; Liu W; Rodriguez A; Abrams JM; Zipursky SL; Jackson GR
    Hum Mol Genet; 2005 Feb; 14(3):357-72. PubMed ID: 15590702
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BimEL as a possible molecular link between proteasome dysfunction and cell death induced by mutant huntingtin.
    Leon R; Bhagavatula N; Ulukpo O; McCollum M; Wei J
    Eur J Neurosci; 2010 Jun; 31(11):1915-25. PubMed ID: 20497470
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
    Atwal RS; Xia J; Pinchev D; Taylor J; Epand RM; Truant R
    Hum Mol Genet; 2007 Nov; 16(21):2600-15. PubMed ID: 17704510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polyglutamine expansion and Huntington's disease.
    Bates GP; Mangiarini L; Wanker EE; Davies SW
    Biochem Soc Trans; 1998 Aug; 26(3):471-5. PubMed ID: 9765898
    [No Abstract]   [Full Text] [Related]  

  • 12. Selection of behaviors and segmental coordination during larval locomotion is disrupted by nuclear polyglutamine inclusions in a new Drosophila Huntington's disease-like model.
    Nishimura Y; Yalgin C; Akimoto S; Doumanis J; Sasajima R; Nukina N; Miyakawa H; Moore AW; Morimoto T
    J Neurogenet; 2010 Dec; 24(4):194-206. PubMed ID: 21087194
    [TBL] [Abstract][Full Text] [Related]  

  • 13. AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's disease.
    Zuleta A; Vidal RL; Armentano D; Parsons G; Hetz C
    Biochem Biophys Res Commun; 2012 Apr; 420(3):558-63. PubMed ID: 22445760
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies.
    Schipper-Krom S; Juenemann K; Jansen AH; Wiemhoefer A; van den Nieuwendijk R; Smith DL; Hink MA; Bates GP; Overkleeft H; Ovaa H; Reits E
    FEBS Lett; 2014 Jan; 588(1):151-9. PubMed ID: 24291262
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease.
    Truant R; Atwal RS; Burtnik A
    Prog Neurobiol; 2007 Nov; 83(4):211-27. PubMed ID: 17240517
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease.
    Valencia A; Reeves PB; Sapp E; Li X; Alexander J; Kegel KB; Chase K; Aronin N; DiFiglia M
    J Neurosci Res; 2010 Jan; 88(1):179-90. PubMed ID: 19642201
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease.
    Weiss A; Klein C; Woodman B; Sathasivam K; Bibel M; Régulier E; Bates GP; Paganetti P
    J Neurochem; 2008 Feb; 104(3):846-58. PubMed ID: 17986219
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polyglutamine expansion in huntingtin alters its interaction with phospholipids.
    Kegel KB; Sapp E; Alexander J; Valencia A; Reeves P; Li X; Masso N; Sobin L; Aronin N; DiFiglia M
    J Neurochem; 2009 Sep; 110(5):1585-97. PubMed ID: 19566678
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Polyglutamine expansion in huntingtin increases its insertion into lipid bilayers.
    Kegel KB; Schewkunow V; Sapp E; Masso N; Wanker EE; DiFiglia M; Goldmann WH
    Biochem Biophys Res Commun; 2009 Sep; 387(3):472-5. PubMed ID: 19607813
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sigma-1 receptor is involved in degradation of intranuclear inclusions in a cellular model of Huntington's disease.
    Miki Y; Tanji K; Mori F; Wakabayashi K
    Neurobiol Dis; 2015 Feb; 74():25-31. PubMed ID: 25449906
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.