BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

399 related articles for article (PubMed ID: 24389668)

  • 1. Blocking the interaction between HIV-1 integrase and human LEDGF/p75: mutational studies, virtual screening and molecular dynamics simulations.
    Reddy KK; Singh P; Singh SK
    Mol Biosyst; 2014 Mar; 10(3):526-36. PubMed ID: 24389668
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insights into the interactions between HIV-1 integrase and human LEDGF/p75 by molecular dynamics simulation and free energy calculation.
    Zhao Y; Li W; Zeng J; Liu G; Tang Y
    Proteins; 2008 Aug; 72(2):635-45. PubMed ID: 18247352
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
    De Luca L; Barreca ML; Ferro S; Christ F; Iraci N; Gitto R; Monforte AM; Debyser Z; Chimirri A
    ChemMedChem; 2009 Aug; 4(8):1311-6. PubMed ID: 19565598
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational studies of the interaction between the HIV-1 integrase tetramer and the cofactor LEDGF/p75: insights from molecular dynamics simulations and the informational spectrum method.
    Tintori C; Veljkovic N; Veljkovic V; Botta M
    Proteins; 2010 Dec; 78(16):3396-408. PubMed ID: 20878714
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-based virtual screening toward the discovery of novel inhibitors for impeding the protein-protein interaction between HIV-1 integrase and human lens epithelium-derived growth factor (LEDGF/p75).
    Panwar U; Singh SK
    J Biomol Struct Dyn; 2018 Sep; 36(12):3199-3217. PubMed ID: 28948865
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of the LEDGF/p75 binding site in HIV-1 integrase.
    Busschots K; Voet A; De Maeyer M; Rain JC; Emiliani S; Benarous R; Desender L; Debyser Z; Christ F
    J Mol Biol; 2007 Feb; 365(5):1480-92. PubMed ID: 17137594
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy.
    Christ F; Debyser Z
    Virology; 2013 Jan; 435(1):102-9. PubMed ID: 23217620
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insight into the fundamental interactions between LEDGF binding site inhibitors and integrase combining docking and molecular dynamics simulations.
    De Luca L; Morreale F; Chimirri A
    J Chem Inf Model; 2012 Dec; 52(12):3245-54. PubMed ID: 23194297
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor.
    Cavalluzzo C; Christ F; Voet A; Sharma A; Singh BK; Zhang KY; Lescrinier E; De Maeyer M; Debyser Z; Van der Eycken E
    J Pept Sci; 2013 Oct; 19(10):651-8. PubMed ID: 24014475
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor.
    De Luca L; Ferro S; Gitto R; Barreca ML; Agnello S; Christ F; Debyser Z; Chimirri A
    Bioorg Med Chem; 2010 Nov; 18(21):7515-21. PubMed ID: 20850978
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75.
    Bartholomeeusen K; De Rijck J; Busschots K; Desender L; Gijsbers R; Emiliani S; Benarous R; Debyser Z; Christ F
    J Mol Biol; 2007 Sep; 372(2):407-21. PubMed ID: 17669426
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular modeling study on the allosteric inhibition mechanism of HIV-1 integrase by LEDGF/p75 binding site inhibitors.
    Xue W; Liu H; Yao X
    PLoS One; 2014; 9(3):e90799. PubMed ID: 24599328
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitors of the interactions between HIV-1 IN and the cofactor LEDGF/p75.
    De Luca L; Ferro S; Morreale F; De Grazia S; Chimirri A
    ChemMedChem; 2011 Jul; 6(7):1184-91. PubMed ID: 21506277
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New scaffolds of natural origin as Integrase-LEDGF/p75 interaction inhibitors: virtual screening and activity assays.
    De Luca L; Morreale F; Christ F; Debyser Z; Ferro S; Gitto R
    Eur J Med Chem; 2013 Oct; 68():405-11. PubMed ID: 23994868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1,4-Bis(5-(naphthalen-1-yl)thiophen-2-yl)naphthalene, a small molecule, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular Lens epithelium-derived growth factor.
    Gu WG; Ip DT; Liu SJ; Chan JH; Wang Y; Zhang X; Zheng YT; Wan DC
    Chem Biol Interact; 2014 Apr; 213():21-7. PubMed ID: 24480521
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Virtual-screening targeting Human Immunodeficiency Virus type 1 integrase-lens epithelium-derived growth factor/p75 interaction for drug development.
    Gu WG; Liu BN; Yuan JF
    J Drug Target; 2015 Feb; 23(2):134-9. PubMed ID: 25230778
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [LEDGF/p75: a novel target for anti-HIV therapy and advances in the study of its related inhibitors].
    Chen WM; Liu XY
    Yao Xue Xue Bao; 2009 Sep; 44(9):953-60. PubMed ID: 20055168
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.
    Hombrouck A; De Rijck J; Hendrix J; Vandekerckhove L; Voet A; De Maeyer M; Witvrouw M; Engelborghs Y; Christ F; Gijsbers R; Debyser Z
    PLoS Pathog; 2007 Mar; 3(3):e47. PubMed ID: 17397262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Computational and synthetic approaches for developing Lavendustin B derivatives as allosteric inhibitors of HIV-1 integrase.
    Agharbaoui FE; Hoyte AC; Ferro S; Gitto R; Buemi MR; Fuchs JR; Kvaratskhelia M; De Luca L
    Eur J Med Chem; 2016 Nov; 123():673-683. PubMed ID: 27517812
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the HIV-1 integrase chromatin- and LEDGF/p75-binding abilities by mutagenic analysis within the catalytic core domain of integrase.
    Zheng Y; Ao Z; Jayappa KD; Yao X
    Virol J; 2010 Mar; 7():68. PubMed ID: 20331877
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.