210 related articles for article (PubMed ID: 24391488)
1. A multi-scale model of hepcidin promoter regulation reveals factors controlling systemic iron homeostasis.
Casanovas G; Banerji A; d'Alessio F; Muckenthaler MU; Legewie S
PLoS Comput Biol; 2014 Jan; 10(1):e1003421. PubMed ID: 24391488
[TBL] [Abstract][Full Text] [Related]
2. Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD.
Casanovas G; Mleczko-Sanecka K; Altamura S; Hentze MW; Muckenthaler MU
J Mol Med (Berl); 2009 May; 87(5):471-80. PubMed ID: 19229506
[TBL] [Abstract][Full Text] [Related]
3. Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness.
Truksa J; Lee P; Beutler E
Blood; 2009 Jan; 113(3):688-95. PubMed ID: 18997172
[TBL] [Abstract][Full Text] [Related]
4. Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.
Finberg KE; Whittlesey RL; Fleming MD; Andrews NC
Blood; 2010 May; 115(18):3817-26. PubMed ID: 20200349
[TBL] [Abstract][Full Text] [Related]
5. Hepcidin and the BMP-SMAD pathway: An unexpected liaison.
Silvestri L; Nai A; Dulja A; Pagani A
Vitam Horm; 2019; 110():71-99. PubMed ID: 30798817
[TBL] [Abstract][Full Text] [Related]
6. Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice.
Poli M; Anower-E-Khuda F; Asperti M; Ruzzenenti P; Gryzik M; Denardo A; Gordts PLSM; Arosio P; Esko JD
J Biol Chem; 2019 Sep; 294(36):13292-13303. PubMed ID: 31315930
[TBL] [Abstract][Full Text] [Related]
7. Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.
Mleczko-Sanecka K; Roche F; da Silva AR; Call D; D'Alessio F; Ragab A; Lapinski PE; Ummanni R; Korf U; Oakes C; Damm G; D'Alessandro LA; Klingmüller U; King PD; Boutros M; Hentze MW; Muckenthaler MU
Blood; 2014 Mar; 123(10):1574-85. PubMed ID: 24385536
[TBL] [Abstract][Full Text] [Related]
8. Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.
Canali S; Zumbrennen-Bullough KB; Core AB; Wang CY; Nairz M; Bouley R; Swirski FK; Babitt JL
Blood; 2017 Jan; 129(4):405-414. PubMed ID: 27864295
[TBL] [Abstract][Full Text] [Related]
9. SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression.
Mleczko-Sanecka K; Casanovas G; Ragab A; Breitkopf K; Müller A; Boutros M; Dooley S; Hentze MW; Muckenthaler MU
Blood; 2010 Apr; 115(13):2657-65. PubMed ID: 20040761
[TBL] [Abstract][Full Text] [Related]
10. Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidin.
Goh JB; Wallace DF; Hong W; Subramaniam VN
Sci Rep; 2015 Sep; 5():13986. PubMed ID: 26358513
[TBL] [Abstract][Full Text] [Related]
11. MicroRNA-130a is up-regulated in mouse liver by iron deficiency and targets the bone morphogenetic protein (BMP) receptor ALK2 to attenuate BMP signaling and hepcidin transcription.
Zumbrennen-Bullough KB; Wu Q; Core AB; Canali S; Chen W; Theurl I; Meynard D; Babitt JL
J Biol Chem; 2014 Aug; 289(34):23796-808. PubMed ID: 25002578
[TBL] [Abstract][Full Text] [Related]
12. Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation.
Asperti M; Stuemler T; Poli M; Gryzik M; Lifshitz L; Meyron-Holtz EG; Vlodavsky I; Arosio P
PLoS One; 2016; 11(10):e0164183. PubMed ID: 27711215
[TBL] [Abstract][Full Text] [Related]
13. Hypoxia inhibits hepcidin expression in HuH7 hepatoma cells via decreased SMAD4 signaling.
Chaston TB; Matak P; Pourvali K; Srai SK; McKie AT; Sharp PA
Am J Physiol Cell Physiol; 2011 Apr; 300(4):C888-95. PubMed ID: 21289291
[TBL] [Abstract][Full Text] [Related]
14. Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes.
Chen S; Feng T; Vujić Spasić M; Altamura S; Breitkopf-Heinlein K; Altenöder J; Weiss TS; Dooley S; Muckenthaler MU
J Biol Chem; 2016 Jun; 291(25):13160-74. PubMed ID: 27129231
[TBL] [Abstract][Full Text] [Related]
15. Friend of GATA and GATA-6 modulate the transcriptional up-regulation of hepcidin in hepatocytes during inflammation.
Bagu ET; Layoun A; Calvé A; Santos MM
Biometals; 2013 Dec; 26(6):1051-65. PubMed ID: 24179092
[TBL] [Abstract][Full Text] [Related]
16. Low hepcidin accounts for the proinflammatory status associated with iron deficiency.
Pagani A; Nai A; Corna G; Bosurgi L; Rovere-Querini P; Camaschella C; Silvestri L
Blood; 2011 Jul; 118(3):736-46. PubMed ID: 21628413
[TBL] [Abstract][Full Text] [Related]
17. The role of STAT, AP-1, E-box and TIEG motifs in the regulation of hepcidin by IL-6 and BMP-9: lessons from human HAMP and murine Hamp1 and Hamp2 gene promoters.
Truksa J; Lee P; Beutler E
Blood Cells Mol Dis; 2007; 39(3):255-62. PubMed ID: 17689119
[TBL] [Abstract][Full Text] [Related]
18. Hepcidin-mediated hypoferremic response to acute inflammation requires a threshold of Bmp6/Hjv/Smad signaling.
Fillebeen C; Wilkinson N; Charlebois E; Katsarou A; Wagner J; Pantopoulos K
Blood; 2018 Oct; 132(17):1829-1841. PubMed ID: 30213871
[TBL] [Abstract][Full Text] [Related]
19. The regulation of hepcidin expression by serum treatment: requirements of the BMP response element and STAT- and AP-1-binding sites.
Kanamori Y; Murakami M; Matsui T; Funaba M
Gene; 2014 Nov; 551(2):119-26. PubMed ID: 25151311
[TBL] [Abstract][Full Text] [Related]
20. Orphan Nuclear Receptor ERRγ Is a Novel Transcriptional Regulator of IL-6 Mediated Hepatic BMP6 Gene Expression in Mice.
Radhakrishnan K; Kim YH; Jung YS; Kim J; Kim DK; Cho SJ; Lee IK; Dooley S; Lee CH; Choi HS
Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 32998264
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
