284 related articles for article (PubMed ID: 24392030)
1. Human A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neurons.
Li L; Nadanaciva S; Berger Z; Shen W; Paumier K; Schwartz J; Mou K; Loos P; Milici AJ; Dunlop J; Hirst WD
PLoS One; 2013; 8(12):e85815. PubMed ID: 24392030
[TBL] [Abstract][Full Text] [Related]
2. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.
Martin LJ; Pan Y; Price AC; Sterling W; Copeland NG; Jenkins NA; Price DL; Lee MK
J Neurosci; 2006 Jan; 26(1):41-50. PubMed ID: 16399671
[TBL] [Abstract][Full Text] [Related]
3. Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
Pavia-Collado R; Cóppola-Segovia V; Miquel-Rio L; Alarcón-Aris D; Rodríguez-Aller R; Torres-López M; Paz V; Ruiz-Bronchal E; Campa L; Artigas F; Montefeltro A; Revilla R; Bortolozzi A
Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33805843
[TBL] [Abstract][Full Text] [Related]
4. Involvement of mortalin/GRP75/mthsp70 in the mitochondrial impairments induced by A53T mutant α-synuclein.
Liu FT; Chen Y; Yang YJ; Yang L; Yu M; Zhao J; Wu JJ; Huang F; Liu W; Ding ZT; Wang J
Brain Res; 2015 Apr; 1604():52-61. PubMed ID: 25665531
[TBL] [Abstract][Full Text] [Related]
5. A53T Mutant Alpha-Synuclein Induces Tau-Dependent Postsynaptic Impairment Independently of Neurodegenerative Changes.
Teravskis PJ; Covelo A; Miller EC; Singh B; Martell-Martínez HA; Benneyworth MA; Gallardo C; Oxnard BR; Araque A; Lee MK; Liao D
J Neurosci; 2018 Nov; 38(45):9754-9767. PubMed ID: 30249789
[TBL] [Abstract][Full Text] [Related]
6. Behavioral characterization of A53T mice reveals early and late stage deficits related to Parkinson's disease.
Paumier KL; Sukoff Rizzo SJ; Berger Z; Chen Y; Gonzales C; Kaftan E; Li L; Lotarski S; Monaghan M; Shen W; Stolyar P; Vasilyev D; Zaleska M; D Hirst W; Dunlop J
PLoS One; 2013; 8(8):e70274. PubMed ID: 23936403
[TBL] [Abstract][Full Text] [Related]
7. Impairment of mitochondria dynamics by human A53T α-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease.
Melo TQ; van Zomeren KC; Ferrari MF; Boddeke HW; Copray JC
Exp Brain Res; 2017 Mar; 235(3):731-742. PubMed ID: 27866262
[TBL] [Abstract][Full Text] [Related]
8. splitGFP Technology Reveals Dose-Dependent ER-Mitochondria Interface Modulation by α-Synuclein A53T and A30P Mutants.
Calì T; Ottolini D; Vicario M; Catoni C; Vallese F; Cieri D; Barazzuol L; Brini M
Cells; 2019 Sep; 8(9):. PubMed ID: 31547305
[TBL] [Abstract][Full Text] [Related]
9. Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.
Lee MK; Stirling W; Xu Y; Xu X; Qui D; Mandir AS; Dawson TM; Copeland NG; Jenkins NA; Price DL
Proc Natl Acad Sci U S A; 2002 Jun; 99(13):8968-73. PubMed ID: 12084935
[TBL] [Abstract][Full Text] [Related]
10. Neuroprotection of α-synuclein under acute and chronic rotenone and maneb treatment is abolished by its familial Parkinson's disease mutations A30P, A53T and E46K.
Choong CJ; Say YH
Neurotoxicology; 2011 Dec; 32(6):857-63. PubMed ID: 21658409
[TBL] [Abstract][Full Text] [Related]
11. AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.
Ip CW; Klaus LC; Karikari AA; Visanji NP; Brotchie JM; Lang AE; Volkmann J; Koprich JB
Acta Neuropathol Commun; 2017 Feb; 5(1):11. PubMed ID: 28143577
[TBL] [Abstract][Full Text] [Related]
12. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity.
Smith WW; Jiang H; Pei Z; Tanaka Y; Morita H; Sawa A; Dawson VL; Dawson TM; Ross CA
Hum Mol Genet; 2005 Dec; 14(24):3801-11. PubMed ID: 16239241
[TBL] [Abstract][Full Text] [Related]
13. A split-GFP tool reveals differences in the sub-mitochondrial distribution of wt and mutant alpha-synuclein.
Vicario M; Cieri D; Vallese F; Catoni C; Barazzuol L; Berto P; Grinzato A; Barbieri L; Brini M; Calì T
Cell Death Dis; 2019 Nov; 10(11):857. PubMed ID: 31719530
[TBL] [Abstract][Full Text] [Related]
14. Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration.
Martin LJ
Rev Neurosci; 2007; 18(2):115-36. PubMed ID: 17593875
[TBL] [Abstract][Full Text] [Related]
15. The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity.
Butler EK; Voigt A; Lutz AK; Toegel JP; Gerhardt E; Karsten P; Falkenburger B; Reinartz A; Winklhofer KF; Schulz JB
PLoS Genet; 2012 Feb; 8(2):e1002488. PubMed ID: 22319455
[TBL] [Abstract][Full Text] [Related]
16. Changes in Drp1 Function and Mitochondrial Morphology Are Associated with the α-Synuclein Pathology in a Transgenic Mouse Model of Parkinson's Disease.
Portz P; Lee MK
Cells; 2021 Apr; 10(4):. PubMed ID: 33924585
[TBL] [Abstract][Full Text] [Related]
17. Alpha-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson's disease.
Xie W; Chung KK
J Neurochem; 2012 Jul; 122(2):404-14. PubMed ID: 22537068
[TBL] [Abstract][Full Text] [Related]
18. Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2.
Daher JP; Pletnikova O; Biskup S; Musso A; Gellhaar S; Galter D; Troncoso JC; Lee MK; Dawson TM; Dawson VL; Moore DJ
Hum Mol Genet; 2012 Jun; 21(11):2420-31. PubMed ID: 22357653
[TBL] [Abstract][Full Text] [Related]
19. Dl-3-n-Butylphthalide Alleviates Behavioral and Cognitive Symptoms Via Modulating Mitochondrial Dynamics in the A53T-α-Synuclein Mouse Model of Parkinson's Disease.
Li H; Wang H; Zhang L; Wang M; Li Y
Front Neurosci; 2021; 15():647266. PubMed ID: 34121985
[TBL] [Abstract][Full Text] [Related]
20. Cx3cr1-deficiency exacerbates alpha-synuclein-A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease.
Castro-Sánchez S; García-Yagüe ÁJ; López-Royo T; Casarejos M; Lanciego JL; Lastres-Becker I
Glia; 2018 Aug; 66(8):1752-1762. PubMed ID: 29624735
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]