185 related articles for article (PubMed ID: 24393126)
1. Synthetic phosphorylation of p38α recapitulates protein kinase activity.
Chooi KP; Galan SR; Raj R; McCullagh J; Mohammed S; Jones LH; Davis BG
J Am Chem Soc; 2014 Feb; 136(5):1698-701. PubMed ID: 24393126
[TBL] [Abstract][Full Text] [Related]
2. Precisely ordered phosphorylation reactions in the p38 mitogen-activated protein (MAP) kinase cascade.
Humphreys JM; Piala AT; Akella R; He H; Goldsmith EJ
J Biol Chem; 2013 Aug; 288(32):23322-30. PubMed ID: 23744074
[TBL] [Abstract][Full Text] [Related]
3. A temperature-dependent conformational shift in p38α MAPK substrate-binding region associated with changes in substrate phosphorylation profile.
Deredge D; Wintrode PL; Tulapurkar ME; Nagarsekar A; Zhang Y; Weber DJ; Shapiro P; Hasday JD
J Biol Chem; 2019 Aug; 294(34):12624-12637. PubMed ID: 31213525
[TBL] [Abstract][Full Text] [Related]
4. Active mutants of the TCR-mediated p38α alternative activation site show changes in the phosphorylation lip and DEF site formation.
Tzarum N; Diskin R; Engelberg D; Livnah O
J Mol Biol; 2011 Feb; 405(5):1154-69. PubMed ID: 21146537
[TBL] [Abstract][Full Text] [Related]
5. Redox-dependent dimerization of p38α mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3.
Bassi R; Burgoyne JR; DeNicola GF; Rudyk O; DeSantis V; Charles RL; Eaton P; Marber MS
J Biol Chem; 2017 Sep; 292(39):16161-16173. PubMed ID: 28739872
[TBL] [Abstract][Full Text] [Related]
6. DEF pocket in p38α facilitates substrate selectivity and mediates autophosphorylation.
Tzarum N; Komornik N; Ben Chetrit D; Engelberg D; Livnah O
J Biol Chem; 2013 Jul; 288(27):19537-47. PubMed ID: 23671282
[TBL] [Abstract][Full Text] [Related]
7. Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38alpha MAP kinase.
Sours KM; Kwok SC; Rachidi T; Lee T; Ring A; Hoofnagle AN; Resing KA; Ahn NG
J Mol Biol; 2008 Jun; 379(5):1075-93. PubMed ID: 18501927
[TBL] [Abstract][Full Text] [Related]
8. The kinetic mechanism of the dual phosphorylation of the ATF2 transcription factor by p38 mitogen-activated protein (MAP) kinase alpha. Implications for signal/response profiles of MAP kinase pathways.
Waas WF; Lo HH; Dalby KN
J Biol Chem; 2001 Feb; 276(8):5676-84. PubMed ID: 11069918
[TBL] [Abstract][Full Text] [Related]
9. Attenuation of mitochondrial and nuclear p38α signaling: a novel mechanism of estrogen neuroprotection in cerebral ischemia.
Han D; Scott EL; Dong Y; Raz L; Wang R; Zhang Q
Mol Cell Endocrinol; 2015 Jan; 400():21-31. PubMed ID: 25462588
[TBL] [Abstract][Full Text] [Related]
10. Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state.
Bukhtiyarova M; Karpusas M; Northrop K; Namboodiri HV; Springman EB
Biochemistry; 2007 May; 46(19):5687-96. PubMed ID: 17441692
[TBL] [Abstract][Full Text] [Related]
11. Discovery and characterization of a substrate selective p38alpha inhibitor.
Davidson W; Frego L; Peet GW; Kroe RR; Labadia ME; Lukas SM; Snow RJ; Jakes S; Grygon CA; Pargellis C; Werneburg BG
Biochemistry; 2004 Sep; 43(37):11658-71. PubMed ID: 15362850
[TBL] [Abstract][Full Text] [Related]
12. Lipid molecules induce p38α activation via a novel molecular switch.
Tzarum N; Eisenberg-Domovich Y; Gills JJ; Dennis PA; Livnah O
J Mol Biol; 2012 Dec; 424(5):339-53. PubMed ID: 23079240
[TBL] [Abstract][Full Text] [Related]
13. Kinetic and mechanistic studies of p38α MAP kinase phosphorylation by MKK6.
Wang YL; Zhang YY; Lu C; Zhang W; Deng H; Wu JW; Wang J; Wang ZX
FEBS J; 2019 Mar; 286(5):1030-1052. PubMed ID: 30663248
[TBL] [Abstract][Full Text] [Related]
14. p38α Signaling Induces Anoikis and Lumen Formation During Mammary Morphogenesis.
Wen HC; Avivar-Valderas A; Sosa MS; Girnius N; Farias EF; Davis RJ; Aguirre-Ghiso JA
Sci Signal; 2011 May; 4(174):ra34. PubMed ID: 21610252
[TBL] [Abstract][Full Text] [Related]
15. Active mutants of the human p38alpha mitogen-activated protein kinase.
Diskin R; Askari N; Capone R; Engelberg D; Livnah O
J Biol Chem; 2004 Nov; 279(45):47040-9. PubMed ID: 15284239
[TBL] [Abstract][Full Text] [Related]
16. Direct monitoring of the conformational equilibria of the activation loop in the mitogen-activated protein kinase p38α.
Roser P; Weisner J; Simard JR; Rauh D; Drescher M
Chem Commun (Camb); 2018 Oct; 54(85):12057-12060. PubMed ID: 30295691
[TBL] [Abstract][Full Text] [Related]
17. The third conformation of p38α MAP kinase observed in phosphorylated p38α and in solution.
Akella R; Min X; Wu Q; Gardner KH; Goldsmith EJ
Structure; 2010 Dec; 18(12):1571-8. PubMed ID: 21134636
[TBL] [Abstract][Full Text] [Related]
18. Identification of a Novel Inhibitory Allosteric Site in p38α.
Gomez-Gutierrez P; Campos PM; Vega M; Perez JJ
PLoS One; 2016; 11(11):e0167379. PubMed ID: 27898710
[TBL] [Abstract][Full Text] [Related]
19. Discovery and characterization of MAPK-activated protein kinase-2 prevention of activation inhibitors.
Cumming JG; Debreczeni JÉ; Edfeldt F; Evertsson E; Harrison M; Holdgate GA; James MJ; Lamont SG; Oldham K; Sullivan JE; Wells SL
J Med Chem; 2015 Jan; 58(1):278-93. PubMed ID: 25255283
[TBL] [Abstract][Full Text] [Related]
20. Conformational selection vs. induced fit: insights into the binding mechanisms of p38α MAP Kinase inhibitors.
Roser P; Weisner J; Stehle J; Rauh D; Drescher M
Chem Commun (Camb); 2020 Aug; 56(62):8818-8821. PubMed ID: 32749403
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]