These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 24399296)

  • 1. TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.
    Gudey SK; Sundar R; Mu Y; Wallenius A; Zang G; Bergh A; Heldin CH; Landström M
    Sci Signal; 2014 Jan; 7(307):ra2. PubMed ID: 24399296
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.
    Song J; Mu Y; Li C; Bergh A; Miaczynska M; Heldin CH; Landström M
    Oncotarget; 2016 Jan; 7(1):279-92. PubMed ID: 26583432
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.
    Sundar R; Gudey SK; Heldin CH; Landström M
    Cell Cycle; 2015; 14(4):554-65. PubMed ID: 25622187
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.
    Mu Y; Sundar R; Thakur N; Ekman M; Gudey SK; Yakymovych M; Hermansson A; Dimitriou H; Bengoechea-Alonso MT; Ericsson J; Heldin CH; Landström M
    Nat Commun; 2011; 2():330. PubMed ID: 21629263
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RanBPM interacts with TβRI, TRAF6 and curbs TGF induced nuclear accumulation of TβRI.
    Zhang J; Ma W; Tian S; Fan Z; Ma X; Yang X; Zhao Q; Tan K; Chen H; Chen D; Huang BR
    Cell Signal; 2014 Jan; 26(1):162-72. PubMed ID: 24103590
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Association between Presenilin-1 and TRAF6 modulates regulated intramembrane proteolysis of the p75NTR neurotrophin receptor.
    Powell JC; Twomey C; Jain R; McCarthy JV
    J Neurochem; 2009 Jan; 108(1):216-30. PubMed ID: 19012753
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α.
    Hamidi A; Song J; Thakur N; Itoh S; Marcusson A; Bergh A; Heldin CH; Landström M
    Sci Signal; 2017 Jul; 10(486):. PubMed ID: 28676490
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interleukin-1 receptor type 1 is a substrate for gamma-secretase-dependent regulated intramembrane proteolysis.
    Elzinga BM; Twomey C; Powell JC; Harte F; McCarthy JV
    J Biol Chem; 2009 Jan; 284(3):1394-409. PubMed ID: 18996842
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner.
    Sorrentino A; Thakur N; Grimsby S; Marcusson A; von Bulow V; Schuster N; Zhang S; Heldin CH; Landström M
    Nat Cell Biol; 2008 Oct; 10(10):1199-207. PubMed ID: 18758450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Presenilins are novel substrates for TRAF6-mediated ubiquitination.
    Yan R; Farrelly S; McCarthy JV
    Cell Signal; 2013 Sep; 25(9):1769-79. PubMed ID: 23707529
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.
    Yakymovych I; Yakymovych M; Zang G; Mu Y; Bergh A; Landström M; Heldin CH
    J Cell Biol; 2015 Jul; 210(2):319-32. PubMed ID: 26169354
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells.
    Song J; Zhou Y; Yakymovych I; Schmidt A; Li C; Heldin CH; Landström M
    EBioMedicine; 2022 Aug; 82():104155. PubMed ID: 35853811
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway.
    Tu X; Zhang H; Zhang J; Zhao S; Zheng X; Zhang Z; Zhu J; Chen J; Dong L; Zang Y; Zhang J
    J Pathol; 2014 Sep; 234(1):46-59. PubMed ID: 24817606
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A ubiquitin-binding CUE domain in presenilin-1 enables interaction with K63-linked polyubiquitin chains.
    Duggan SP; Yan R; McCarthy JV
    FEBS Lett; 2015 Apr; 589(9):1001-8. PubMed ID: 25796185
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Podoplanin is a substrate of presenilin-1/γ-secretase.
    Yurrita MM; Fernández-Muñoz B; Del Castillo G; Martín-Villar E; Renart J; Quintanilla M
    Int J Biochem Cell Biol; 2014 Jan; 46():68-75. PubMed ID: 24275092
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interactome of transforming growth factor-beta type I receptor (TbetaRI): inhibition of TGFbeta signaling by Epac1.
    Conrotto P; Yakymovych I; Yakymovych M; Souchelnytskyi S
    J Proteome Res; 2007 Jan; 6(1):287-97. PubMed ID: 17203972
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclic AMP enhances TGFβ responses of breast cancer cells by upregulating TGFβ receptor I expression.
    Oerlecke I; Bauer E; Dittmer A; Leyh B; Dittmer J
    PLoS One; 2013; 8(1):e54261. PubMed ID: 23349840
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1.
    Thakur N; Gudey SK; Marcusson A; Fu JY; Bergh A; Heldin CH; Landström M
    Cell Cycle; 2014; 13(15):2400-14. PubMed ID: 25483191
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assembly of TbetaRI:TbetaRII:TGFbeta ternary complex in vitro with receptor extracellular domains is cooperative and isoform-dependent.
    Zúñiga JE; Groppe JC; Cui Y; Hinck CS; Contreras-Shannon V; Pakhomova ON; Yang J; Tang Y; Mendoza V; López-Casillas F; Sun L; Hinck AP
    J Mol Biol; 2005 Dec; 354(5):1052-68. PubMed ID: 16289576
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage.
    Cowan JW; Wang X; Guan R; He K; Jiang J; Baumann G; Black RA; Wolfe MS; Frank SJ
    J Biol Chem; 2005 May; 280(19):19331-42. PubMed ID: 15743767
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.