433 related articles for article (PubMed ID: 24403227)
1. BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.
Ellinghaus P; Heisler I; Unterschemmann K; Haerter M; Beck H; Greschat S; Ehrmann A; Summer H; Flamme I; Oehme F; Thierauch K; Michels M; Hess-Stumpp H; Ziegelbauer K
Cancer Med; 2013 Oct; 2(5):611-24. PubMed ID: 24403227
[TBL] [Abstract][Full Text] [Related]
2. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
Chintala S; Najrana T; Toth K; Cao S; Durrani FA; Pili R; Rustum YM
BMC Cancer; 2012 Jul; 12():293. PubMed ID: 22804960
[TBL] [Abstract][Full Text] [Related]
3. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
Carroll VA; Ashcroft M
Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
[TBL] [Abstract][Full Text] [Related]
4. Activation of hypoxia-induced transcription in normoxia.
Hägg M; Wennström S
Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
[TBL] [Abstract][Full Text] [Related]
5. 18F-FAZA PET imaging response tracks the reoxygenation of tumors in mice upon treatment with the mitochondrial complex I inhibitor BAY 87-2243.
Chang E; Liu H; Unterschemmann K; Ellinghaus P; Liu S; Gekeler V; Cheng Z; Berndorff D; Gambhir SS
Clin Cancer Res; 2015 Jan; 21(2):335-46. PubMed ID: 25381339
[TBL] [Abstract][Full Text] [Related]
6. Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1alpha expression.
Jensen RL; Gillespie D; House P; Layfield L; Shelton C
J Neurosurg; 2004 Mar; 100(3):488-97. PubMed ID: 15035285
[TBL] [Abstract][Full Text] [Related]
7. Increased activation of the hypoxia-inducible factor pathway in varicose veins.
Lim CS; Kiriakidis S; Paleolog EM; Davies AH
J Vasc Surg; 2012 May; 55(5):1427-39. PubMed ID: 22277691
[TBL] [Abstract][Full Text] [Related]
8. Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha.
Chintala S; Tóth K; Cao S; Durrani FA; Vaughan MM; Jensen RL; Rustum YM
Cancer Chemother Pharmacol; 2010 Oct; 66(5):899-911. PubMed ID: 20066420
[TBL] [Abstract][Full Text] [Related]
9. Kinome siRNA screen identifies SMG-1 as a negative regulator of hypoxia-inducible factor-1alpha in hypoxia.
Chen RQ; Yang QK; Chen YL; Oliveira VA; Dalton WS; Fearns C; Lee JD
J Biol Chem; 2009 Jun; 284(25):16752-16758. PubMed ID: 19406746
[TBL] [Abstract][Full Text] [Related]
10. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
Aprelikova O; Chandramouli GV; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
J Cell Biochem; 2004 Jun; 92(3):491-501. PubMed ID: 15156561
[TBL] [Abstract][Full Text] [Related]
11. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
12. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
13. Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix.
Ellingsen C; Andersen LM; Galappathi K; Rofstad EK
BMC Cancer; 2015 Oct; 15():805. PubMed ID: 26502718
[TBL] [Abstract][Full Text] [Related]
14. Gambogic acid inhibits angiogenesis through inhibiting PHD2-VHL-HIF-1α pathway.
Lu N; Hui H; Yang H; Zhao K; Chen Y; You QD; Guo QL
Eur J Pharm Sci; 2013 May; 49(2):220-6. PubMed ID: 23501055
[TBL] [Abstract][Full Text] [Related]
15. BAY 87-2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts.
Helbig L; Koi L; Brüchner K; Gurtner K; Hess-Stumpp H; Unterschemmann K; Baumann M; Zips D; Yaromina A
Radiat Oncol; 2014 Sep; 9():207. PubMed ID: 25234922
[TBL] [Abstract][Full Text] [Related]
16. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
Song X; Yao J; Wang F; Zhou M; Zhou Y; Wang H; Wei L; Zhao L; Li Z; Lu N; Guo Q
Toxicol Appl Pharmacol; 2013 Sep; 271(2):144-55. PubMed ID: 23707765
[TBL] [Abstract][Full Text] [Related]
17. Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.
Said HM; Hagemann C; Carta F; Katzer A; Polat B; Staab A; Scozzafava A; Anacker J; Vince GH; Flentje M; Supuran CT
Bioorg Med Chem; 2013 Jul; 21(13):3949-57. PubMed ID: 23706268
[TBL] [Abstract][Full Text] [Related]
18. Expression of hypoxia-inducible factor 1 alpha in thyroid carcinomas.
Burrows N; Resch J; Cowen RL; von Wasielewski R; Hoang-Vu C; West CM; Williams KJ; Brabant G
Endocr Relat Cancer; 2010 Mar; 17(1):61-72. PubMed ID: 19808899
[TBL] [Abstract][Full Text] [Related]
19. RNA interference targeting hypoxia-inducible factor 1α via a novel multifunctional surfactant attenuates glioma growth in an intracranial mouse model.
Gillespie DL; Aguirre MT; Ravichandran S; Leishman LL; Berrondo C; Gamboa JT; Wang L; King R; Wang X; Tan M; Malamas A; Lu ZR; Jensen RL
J Neurosurg; 2015 Feb; 122(2):331-41. PubMed ID: 25423275
[TBL] [Abstract][Full Text] [Related]
20. Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound.
Park K; Lee HE; Lee SH; Lee D; Lee T; Lee YM
Oncotarget; 2017 Jan; 8(5):7801-7813. PubMed ID: 27999195
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]