BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 24407947)

  • 1. Regional flexibility in the S4-S5 linker regulates hERG channel closed-state stabilization.
    Hull CM; Sokolov S; Van Slyke AC; Claydon TW
    Pflugers Arch; 2014 Oct; 466(10):1911-9. PubMed ID: 24407947
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker.
    Thouta S; Hull CM; Shi YP; Sergeev V; Young J; Cheng YM; Claydon TW
    Biophys J; 2017 Jan; 112(2):300-312. PubMed ID: 28122216
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutations within the S4-S5 linker alter voltage sensor constraints in hERG K+ channels.
    Van Slyke AC; Rezazadeh S; Snopkowski M; Shi P; Allard CR; Claydon TW
    Biophys J; 2010 Nov; 99(9):2841-52. PubMed ID: 21044581
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel.
    Ferrer T; Rupp J; Piper DR; Tristani-Firouzi M
    J Biol Chem; 2006 May; 281(18):12858-64. PubMed ID: 16524878
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating.
    Ng CA; Perry MD; Tan PS; Hill AP; Kuchel PW; Vandenberg JI
    PLoS One; 2012; 7(2):e31640. PubMed ID: 22359612
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.
    Gianulis EC; Liu Q; Trudeau MC
    J Gen Physiol; 2013 Oct; 142(4):351-66. PubMed ID: 24043860
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a-go-go-related gene (hERG) potassium channel.
    de la Peña P; Alonso-Ron C; Machín A; Fernández-Trillo J; Carretero L; Domínguez P; Barros F
    J Biol Chem; 2011 May; 286(21):19065-75. PubMed ID: 21474444
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes.
    Sanguinetti MC; Xu QP
    J Physiol; 1999 Feb; 514 ( Pt 3)(Pt 3):667-75. PubMed ID: 9882738
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gating mechanism of Kv11.1 (hERG) K
    de la Peña P; Domínguez P; Barros F
    Pflugers Arch; 2018 Mar; 470(3):517-536. PubMed ID: 29270671
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening.
    Es-Salah-Lamoureux Z; Fougere R; Xiong PY; Robertson GA; Fedida D
    PLoS One; 2010 May; 5(5):e10876. PubMed ID: 20526358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.
    Alonso-Ron C; de la Peña P; Miranda P; Domínguez P; Barros F
    Biophys J; 2008 May; 94(10):3893-911. PubMed ID: 18222997
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new mechanism of voltage-dependent gating exposed by K
    Tomczak AP; Fernández-Trillo J; Bharill S; Papp F; Panyi G; Stühmer W; Isacoff EY; Pardo LA
    J Gen Physiol; 2017 May; 149(5):577-593. PubMed ID: 28360219
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.
    Perry MD; Wong S; Ng CA; Vandenberg JI
    J Gen Physiol; 2013 Sep; 142(3):275-88. PubMed ID: 23980196
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism.
    Malak OA; Gluhov GS; Grizel AV; Kudryashova KS; Sokolova OS; Loussouarn G
    J Biol Chem; 2019 Apr; 294(16):6506-6521. PubMed ID: 30808709
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Voltage sensor movement in the hERG K+ channel.
    Piper DR; Sanguinetti MC; Tristani-Firouzi M
    Novartis Found Symp; 2005; 266():46-52; discussion 52-6, 95-9. PubMed ID: 16050261
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interactions between voltage sensor and pore domains in a hERG K+ channel model from molecular simulations and the effects of a voltage sensor mutation.
    Colenso CK; Sessions RB; Zhang YH; Hancox JC; Dempsey CE
    J Chem Inf Model; 2013 Jun; 53(6):1358-70. PubMed ID: 23672495
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels.
    Cheng YM; Hull CM; Niven CM; Qi J; Allard CR; Claydon TW
    J Gen Physiol; 2013 Sep; 142(3):289-303. PubMed ID: 23980197
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The S4-S5 linker couples voltage sensing and activation of pacemaker channels.
    Chen J; Mitcheson JS; Tristani-Firouzi M; Lin M; Sanguinetti MC
    Proc Natl Acad Sci U S A; 2001 Sep; 98(20):11277-82. PubMed ID: 11553787
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium.
    Dou Y; Goodchild SJ; Velde RV; Wu Y; Fedida D
    Am J Physiol Cell Physiol; 2013 Aug; 305(4):C468-78. PubMed ID: 23761630
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gate.
    Thouta S; Sokolov S; Abe Y; Clark SJ; Cheng YM; Claydon TW
    Biophys J; 2014 Mar; 106(5):1057-69. PubMed ID: 24606930
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.