BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

399 related articles for article (PubMed ID: 24412751)

  • 1. LRP6 dimerization through its LDLR domain is required for robust canonical Wnt pathway activation.
    Chen J; Yan H; Ren DN; Yin Y; Li Z; He Q; Wo D; Ho MS; Chen Y; Liu Z; Yang J; Liu S; Zhu W
    Cell Signal; 2014 May; 26(5):1068-74. PubMed ID: 24412751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency.
    Ring L; Neth P; Weber C; Steffens S; Faussner A
    Cell Signal; 2014 Feb; 26(2):260-7. PubMed ID: 24269653
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LRP6 mediates Wnt/β-catenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells.
    Peröbner I; Karow M; Jochum M; Neth P
    Int J Biochem Cell Biol; 2012 Nov; 44(11):1970-82. PubMed ID: 22871567
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis.
    Ren DN; Chen J; Li Z; Yan H; Yin Y; Wo D; Zhang J; Ao L; Chen B; Ito TK; Chen Y; Liu Z; Li Y; Yang J; Lu X; Peng Y; Pan L; Zhao Y; Liu S; Zhu W
    Nat Commun; 2015 Apr; 6():6906. PubMed ID: 25902418
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina.
    Singh HD; Ma JX; Takahashi Y
    Biochem Biophys Res Commun; 2021 Mar; 545():8-13. PubMed ID: 33545636
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6.
    MacDonald BT; Semenov MV; Huang H; He X
    PLoS One; 2011; 6(8):e23537. PubMed ID: 21887268
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.
    Nagaoka T; Karasawa H; Turbyville T; Rangel MC; Castro NP; Gonzales M; Baker A; Seno M; Lockett S; Greer YE; Rubin JS; Salomon DS; Bianco C
    Cell Signal; 2013 Jan; 25(1):178-89. PubMed ID: 23022962
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway.
    Hua Y; Yang Y; Li Q; He X; Zhu W; Wang J; Gan X
    J Biol Chem; 2018 Dec; 293(51):19710-19724. PubMed ID: 30361437
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.
    Goel S; Chin EN; Fakhraldeen SA; Berry SM; Beebe DJ; Alexander CM
    J Biol Chem; 2012 May; 287(20):16454-66. PubMed ID: 22433869
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ADP-ribosylation factors 1 and 6 regulate Wnt/β-catenin signaling via control of LRP6 phosphorylation.
    Kim W; Kim SY; Kim T; Kim M; Bae DJ; Choi HI; Kim IS; Jho E
    Oncogene; 2013 Jul; 32(28):3390-6. PubMed ID: 22907437
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation.
    Haÿ E; Buczkowski T; Marty C; Da Nascimento S; Sonnet P; Marie PJ
    J Bone Miner Res; 2012 Sep; 27(9):1852-63. PubMed ID: 22576936
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes.
    Kim I; Pan W; Jones SA; Zhang Y; Zhuang X; Wu D
    J Cell Biol; 2013 Feb; 200(4):419-28. PubMed ID: 23400998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.
    Sebastian A; Hum NR; Murugesh DK; Hatsell S; Economides AN; Loots GG
    PLoS One; 2017; 12(11):e0188264. PubMed ID: 29176883
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Src and Fyn define a new signaling cascade activated by canonical and non-canonical Wnt ligands and required for gene transcription and cell invasion.
    Villarroel A; Del Valle-Pérez B; Fuertes G; Curto J; Ontiveros N; Garcia de Herreros A; Duñach M
    Cell Mol Life Sci; 2020 Mar; 77(5):919-935. PubMed ID: 31312879
    [TBL] [Abstract][Full Text] [Related]  

  • 15. G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.
    Chen M; Philipp M; Wang J; Premont RT; Garrison TR; Caron MG; Lefkowitz RJ; Chen W
    J Biol Chem; 2009 Dec; 284(50):35040-8. PubMed ID: 19801552
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells.
    Lin C; Lu W; Zhang W; Londoño-Joshi AI; Buchsbaum DJ; Bu G; Li Y
    PLoS One; 2013; 8(2):e58102. PubMed ID: 23469146
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine-based signal mediates LRP6 receptor endocytosis and desensitization of Wnt/β-catenin pathway signaling.
    Liu CC; Kanekiyo T; Roth B; Bu G
    J Biol Chem; 2014 Oct; 289(40):27562-70. PubMed ID: 25143377
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins.
    Brennan K; Gonzalez-Sancho JM; Castelo-Soccio LA; Howe LR; Brown AM
    Oncogene; 2004 Jun; 23(28):4873-84. PubMed ID: 15064719
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.
    Nam JS; Turcotte TJ; Smith PF; Choi S; Yoon JK
    J Biol Chem; 2006 May; 281(19):13247-13257. PubMed ID: 16543246
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of the intracellular domains of LRP5 and LRP6 in activating the Wnt canonical pathway.
    Mi K; Johnson GV
    J Cell Biochem; 2005 May; 95(2):328-38. PubMed ID: 15778991
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.