BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 24417355)

  • 1. Metabolism site prediction based on xenobiotic structural formulas and PASS prediction algorithm.
    Rudik AV; Dmitriev AV; Lagunin AA; Filimonov DA; Poroikov VV
    J Chem Inf Model; 2014 Feb; 54(2):498-507. PubMed ID: 24417355
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SOMP: web server for in silico prediction of sites of metabolism for drug-like compounds.
    Rudik A; Dmitriev A; Lagunin A; Filimonov D; Poroikov V
    Bioinformatics; 2015 Jun; 31(12):2046-8. PubMed ID: 25777527
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FAME 2: Simple and Effective Machine Learning Model of Cytochrome P450 Regioselectivity.
    Šícho M; de Bruyn Kops C; Stork C; Svozil D; Kirchmair J
    J Chem Inf Model; 2017 Aug; 57(8):1832-1846. PubMed ID: 28782945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes.
    Zaretzki J; Rydberg P; Bergeron C; Bennett KP; Olsen L; Breneman CM
    J Chem Inf Model; 2012 Jun; 52(6):1637-59. PubMed ID: 22524152
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prediction of cytochrome P450 xenobiotic metabolism: tethered docking and reactivity derived from ligand molecular orbital analysis.
    Tyzack JD; Williamson MJ; Torella R; Glen RC
    J Chem Inf Model; 2013 Jun; 53(6):1294-305. PubMed ID: 23701380
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prediction of metabolites of epoxidation reaction in MetaTox.
    Rudik AV; Dmitriev AV; Bezhentsev VM; Lagunin AA; Filimonov DA; Poroikov VV
    SAR QSAR Environ Res; 2017 Oct; 28(10):833-842. PubMed ID: 29157013
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2D SMARTCyp reactivity-based site of metabolism prediction for major drug-metabolizing cytochrome P450 enzymes.
    Liu R; Liu J; Tawa G; Wallqvist A
    J Chem Inf Model; 2012 Jun; 52(6):1698-712. PubMed ID: 22631565
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In Silico Prediction of Drug-Drug Interactions Mediated by Cytochrome P450 Isoforms.
    Dmitriev AV; Rudik AV; Karasev DA; Pogodin PV; Lagunin AA; Filimonov DA; Poroikov VV
    Pharmaceutics; 2021 Apr; 13(4):. PubMed ID: 33924315
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Computational Prediction of Inhibitors and Inducers of the Major Isoforms of Cytochrome P450.
    Rudik A; Dmitriev A; Lagunin A; Filimonov D; Poroikov V
    Molecules; 2022 Sep; 27(18):. PubMed ID: 36144612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule.
    Mishra NK; Agarwal S; Raghava GP
    BMC Pharmacol; 2010 Jul; 10():8. PubMed ID: 20637097
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel Electrotopological Atomic Descriptors for the Prediction of Xenobiotic Cytochrome P450 Reactions.
    Kaitoh K; Kotera M; Funatsu K
    Mol Inform; 2019 Oct; 38(10):e1900010. PubMed ID: 31187601
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alignment-Based Prediction of Sites of Metabolism.
    de Bruyn Kops C; Friedrich NO; Kirchmair J
    J Chem Inf Model; 2017 Jun; 57(6):1258-1264. PubMed ID: 28520411
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ligand-based models for the isoform specificity of cytochrome P450 3A4, 2D6, and 2C9 substrates.
    Terfloth L; Bienfait B; Gasteiger J
    J Chem Inf Model; 2007; 47(4):1688-701. PubMed ID: 17608404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RS-WebPredictor: a server for predicting CYP-mediated sites of metabolism on drug-like molecules.
    Zaretzki J; Bergeron C; Huang TW; Rydberg P; Swamidass SJ; Breneman CM
    Bioinformatics; 2013 Feb; 29(4):497-8. PubMed ID: 23242264
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Using chemical bond-based method to predict site of metabolism for five biotransformations mediated by CYP 3A4, 2D6, and 2C9.
    Fu X; He S; Du L; Lv Z; Zhang Y; Zhang Q; Wang Y
    Biochem Pharmacol; 2018 Jun; 152():302-314. PubMed ID: 29588194
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms.
    Kirchmair J; Williamson MJ; Tyzack JD; Tan L; Bond PJ; Bender A; Glen RC
    J Chem Inf Model; 2012 Mar; 52(3):617-48. PubMed ID: 22339582
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Classification of cytochrome P450 inhibitors and noninhibitors using combined classifiers.
    Cheng F; Yu Y; Shen J; Yang L; Li W; Liu G; Lee PW; Tang Y
    J Chem Inf Model; 2011 May; 51(5):996-1011. PubMed ID: 21491913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Eight inhibitory monoclonal antibodies define the role of individual P-450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism.
    Yang TJ; Krausz KW; Sai Y; Gonzalez FJ; Gelboin HV
    Drug Metab Dispos; 1999 Jan; 27(1):102-9. PubMed ID: 9884317
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolism of clozapine by cDNA-expressed human cytochrome P450 enzymes.
    Linnet K; Olesen OV
    Drug Metab Dispos; 1997 Dec; 25(12):1379-82. PubMed ID: 9394027
    [TBL] [Abstract][Full Text] [Related]  

  • 20. QNA-Based Prediction of Sites of Metabolism.
    Tarasova O; Rudik A; Dmitriev A; Lagunin A; Filimonov D; Poroikov V
    Molecules; 2017 Dec; 22(12):. PubMed ID: 29194399
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.