308 related articles for article (PubMed ID: 24418013)
1. The discovery of a novel and selective inhibitor of PTP1B over TCPTP: 3D QSAR pharmacophore modeling, virtual screening, synthesis, and biological evaluation.
Ma Y; Jin YY; Wang YL; Wang RL; Lu XH; Kong DX; Xu WR
Chem Biol Drug Des; 2014 Jun; 83(6):697-709. PubMed ID: 24418013
[TBL] [Abstract][Full Text] [Related]
2. Design and synthesis of imidazolidine-2,4-dione derivatives as selective inhibitors by targeting protein tyrosine phosphatase-1B over T-cell protein tyrosine phosphatase.
Ma Y; Sun SX; Cheng XC; Wang SQ; Dong WL; Wang RL; Xu WR
Chem Biol Drug Des; 2013 Nov; 82(5):595-602. PubMed ID: 23848232
[TBL] [Abstract][Full Text] [Related]
3. Virtual Screening of Novel and Selective Inhibitors of Protein Tyrosine Phosphatase 1B over T-Cell Protein Tyrosine Phosphatase Using a Bidentate Inhibition Strategy.
Chen X; Gan Q; Feng C; Liu X; Zhang Q
J Chem Inf Model; 2018 Apr; 58(4):837-847. PubMed ID: 29608303
[TBL] [Abstract][Full Text] [Related]
4. Diphenylether derivative as selective inhibitor of protein tyrosine phosphatase 1B (PTP1B) over t-cell protein tyrosine phosphatase (TCPTP) identified through virtual screening.
Reddy MV; Ghadiyaram C; Panigrahi SK; Hosahalli S; Mangamoori LN
Mini Rev Med Chem; 2013 Oct; 13(11):1602-6. PubMed ID: 24000798
[TBL] [Abstract][Full Text] [Related]
5. Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site.
Du Y; Zhang Y; Ling H; Li Q; Shen J
Eur J Med Chem; 2018 Jan; 144():692-700. PubMed ID: 29289892
[TBL] [Abstract][Full Text] [Related]
6. The design strategy of selective PTP1B inhibitors over TCPTP.
Li X; Wang L; Shi D
Bioorg Med Chem; 2016 Aug; 24(16):3343-52. PubMed ID: 27353889
[TBL] [Abstract][Full Text] [Related]
7. Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors.
Zhang R; Yu R; Xu Q; Li X; Luo J; Jiang B; Wang L; Guo S; Wu N; Shi D
Eur J Med Chem; 2017 Jul; 134():24-33. PubMed ID: 28395151
[TBL] [Abstract][Full Text] [Related]
8. Discovery of novel PTP1B inhibitors via pharmacophore-oriented scaffold hopping from Ertiprotafib.
Liu JZ; Zhang SE; Nie F; Yang Y; Tang YB; Yin W; Tian JY; Ye F; Xiao Z
Bioorg Med Chem Lett; 2013 Dec; 23(23):6217-22. PubMed ID: 24148325
[TBL] [Abstract][Full Text] [Related]
9. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity.
Liu P; Du Y; Song L; Shen J; Li Q
Eur J Med Chem; 2016 Aug; 118():27-33. PubMed ID: 27123900
[TBL] [Abstract][Full Text] [Related]
10. In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach.
Rao GS; Ramachandran MV; Bajaj JS
J Biomol Struct Dyn; 2006 Feb; 23(4):377-84. PubMed ID: 16363874
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and biological evaluation of 2-substituted ethenesulfonic acid ester derivatives as selective PTP1B inhibitors.
Liu J; Deng X; Jin Y; Xu B; Liu W; Jiang F; Fu L
Pharmazie; 2015 Jul; 70(7):446-51. PubMed ID: 26373204
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B.
Li XQ; Xu Q; Luo J; Wang LJ; Jiang B; Zhang RS; Shi DY
Eur J Med Chem; 2017 Aug; 136():348-359. PubMed ID: 28511130
[TBL] [Abstract][Full Text] [Related]
13. Investigation of selective binding of inhibitors to PTP1B and TCPTP by accelerated molecular dynamics simulations.
Chen X; Gan Q; Feng C; Liu X; Zhang Q
J Biomol Struct Dyn; 2019 Sep; 37(14):3697-3706. PubMed ID: 30238851
[TBL] [Abstract][Full Text] [Related]
14. Screening and identification of potential PTP1B allosteric inhibitors using in silico and in vitro approaches.
Shinde RN; Kumar GS; Eqbal S; Sobhia ME
PLoS One; 2018; 13(6):e0199020. PubMed ID: 29912965
[TBL] [Abstract][Full Text] [Related]
15. Identification of novel PTP1B inhibitors by pharmacophore based virtual screening, scaffold hopping and docking.
Balaramnavar VM; Srivastava R; Rahuja N; Gupta S; Rawat AK; Varshney S; Chandasana H; Chhonker YS; Doharey PK; Kumar S; Gautam S; Srivastava SP; Bhatta RS; Saxena JK; Gaikwad AN; Srivastava AK; Saxena AK
Eur J Med Chem; 2014 Nov; 87():578-94. PubMed ID: 25299681
[TBL] [Abstract][Full Text] [Related]
16. Identification of natural products as selective PTP1B inhibitors via virtual screening.
Yang Y; Tian JY; Ye F; Xiao Z
Bioorg Chem; 2020 May; 98():103706. PubMed ID: 32199302
[TBL] [Abstract][Full Text] [Related]
17. Studies of the mechanism of selectivity of protein tyrosine phosphatase 1B (PTP1B) bidentate inhibitors using molecular dynamics simulations and free energy calculations.
Fang L; Zhang H; Cui W; Ji M
J Chem Inf Model; 2008 Oct; 48(10):2030-41. PubMed ID: 18831546
[TBL] [Abstract][Full Text] [Related]
18. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.
Zhang S; Zhang ZY
Drug Discov Today; 2007 May; 12(9-10):373-81. PubMed ID: 17467573
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors.
Wang WL; Huang C; Gao LX; Tang CL; Wang JQ; Wu MC; Sheng L; Chen HJ; Nan FJ; Li JY; Li J; Feng B
Bioorg Med Chem Lett; 2014 Apr; 24(8):1889-94. PubMed ID: 24684845
[TBL] [Abstract][Full Text] [Related]
20. Structure-based virtual screening approach to identify novel classes of PTP1B inhibitors.
Park H; Bhattarai BR; Ham SW; Cho H
Eur J Med Chem; 2009 Aug; 44(8):3280-4. PubMed ID: 19269068
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
