BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 24418258)

  • 1. Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1.
    Asai H; Ikezu S; Woodbury ME; Yonemoto GM; Cui L; Ikezu T
    Am J Pathol; 2014 Mar; 184(3):808-18. PubMed ID: 24418258
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tau-tubulin kinase.
    Ikezu S; Ikezu T
    Front Mol Neurosci; 2014; 7():33. PubMed ID: 24808823
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration.
    Taylor LM; McMillan PJ; Liachko NF; Strovas TJ; Ghetti B; Bird TD; Keene CD; Kraemer BC
    Mol Neurodegener; 2018 Feb; 13(1):7. PubMed ID: 29409526
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tau-tubulin kinase 1 enhances prefibrillar tau aggregation and motor neuron degeneration in P301L FTDP-17 tau-mutant mice.
    Xu J; Sato S; Okuyama S; Swan RJ; Jacobsen MT; Strunk E; Ikezu T
    FASEB J; 2010 Aug; 24(8):2904-15. PubMed ID: 20354135
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates.
    Vega IE; Cui L; Propst JA; Hutton ML; Lee G; Yen SH
    Brain Res Mol Brain Res; 2005 Aug; 138(2):135-44. PubMed ID: 15913839
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice.
    McMillan P; Wheeler J; Gatlin RE; Taylor L; Strovas T; Baum M; Bird TD; Latimer C; Keene CD; Kraemer BC; Liachko NF
    Acta Neuropathol Commun; 2020 Nov; 8(1):200. PubMed ID: 33228809
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models.
    Ikezu S; Ingraham Dixie KL; Koro L; Watanabe T; Kaibuchi K; Ikezu T
    Acta Neuropathol Commun; 2020 Feb; 8(1):12. PubMed ID: 32019603
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy.
    Koller EJ; Gonzalez De La Cruz E; Machula T; Ibanez KR; Lin WL; Williams T; Riffe CJ; Ryu D; Strang KH; Liu X; Janus C; Golde TE; Dickson D; Giasson BI; Chakrabarty P
    Hum Mol Genet; 2019 Oct; 28(19):3255-3269. PubMed ID: 31261380
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylated p38MAPK specific antibodies cross-react with sarkosyl-insoluble hyperphosphorylated tau proteins.
    Sahara N; Vega IE; Ishizawa T; Lewis J; McGowan E; Hutton M; Dickson D; Yen SH
    J Neurochem; 2004 Aug; 90(4):829-38. PubMed ID: 15287888
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L).
    Ramsden M; Kotilinek L; Forster C; Paulson J; McGowan E; SantaCruz K; Guimaraes A; Yue M; Lewis J; Carlson G; Hutton M; Ashe KH
    J Neurosci; 2005 Nov; 25(46):10637-47. PubMed ID: 16291936
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Long non-coding RNA 00507/miRNA-181c-5p/TTBK1/MAPT axis regulates tau hyperphosphorylation in Alzheimer's disease.
    Yan Y; Yan H; Teng Y; Wang Q; Yang P; Zhang L; Cheng H; Fu S
    J Gene Med; 2020 Dec; 22(12):e3268. PubMed ID: 32891070
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies.
    Higuchi M; Zhang B; Forman MS; Yoshiyama Y; Trojanowski JQ; Lee VM
    J Neurosci; 2005 Oct; 25(41):9434-43. PubMed ID: 16221853
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice.
    Yukawa K; Yamamoto-Mcguire S; Cafaro L; Hong C; Kamme F; Ikezu T; Ikezu S
    Acta Neuropathol Commun; 2023 Oct; 11(1):166. PubMed ID: 37853497
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Co-localization of glycogen synthase kinase-3 with neurofibrillary tangles and granulovacuolar degeneration in transgenic mice.
    Ishizawa T; Sahara N; Ishiguro K; Kersh J; McGowan E; Lewis J; Hutton M; Dickson DW; Yen SH
    Am J Pathol; 2003 Sep; 163(3):1057-67. PubMed ID: 12937146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1.
    Sato S; Xu J; Okuyama S; Martinez LB; Walsh SM; Jacobsen MT; Swan RJ; Schlautman JD; Ciborowski P; Ikezu T
    J Neurosci; 2008 Dec; 28(53):14511-21. PubMed ID: 19118186
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites.
    Dillon GM; Henderson JL; Bao C; Joyce JA; Calhoun M; Amaral B; King KW; Bajrami B; Rabah D
    PLoS One; 2020; 15(4):e0228771. PubMed ID: 32255788
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice.
    Rao MV; McBrayer MK; Campbell J; Kumar A; Hashim A; Sershen H; Stavrides PH; Ohno M; Hutton M; Nixon RA
    J Neurosci; 2014 Jul; 34(28):9222-34. PubMed ID: 25009256
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sensory Neurons from Tau Transgenic Mice and Their Utility in Drug Screening.
    Tolkovsky AM; Brelstaff J
    Methods Mol Biol; 2018; 1727():93-105. PubMed ID: 29222775
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GSPE interferes with tau aggregation in vivo: implication for treating tauopathy.
    Santa-Maria I; Diaz-Ruiz C; Ksiezak-Reding H; Chen A; Ho L; Wang J; Pasinetti GM
    Neurobiol Aging; 2012 Sep; 33(9):2072-81. PubMed ID: 22054871
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease.
    Stozicka Z; Zilka N; Novak P; Kovacech B; Bugos O; Novak M
    J Neuroinflammation; 2010 Oct; 7():64. PubMed ID: 20937161
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.