BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 24424093)

  • 1. Amyloid β binds procaspase-9 to inhibit assembly of Apaf-1 apoptosome and intrinsic apoptosis pathway.
    Sharoar MG; Islam MI; Shahnawaz M; Shin SY; Park IS
    Biochim Biophys Acta; 2014 Apr; 1843(4):685-93. PubMed ID: 24424093
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Limited activation of the intrinsic apoptotic pathway plays a main role in amyloid-β-induced apoptosis without eliciting the activation of the extrinsic apoptotic pathway.
    Islam MI; Sharoar MG; Ryu EK; Park IS
    Int J Mol Med; 2017 Dec; 40(6):1971-1982. PubMed ID: 29039468
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A molecular view on signal transduction by the apoptosome.
    Reubold TF; Eschenburg S
    Cell Signal; 2012 Jul; 24(7):1420-5. PubMed ID: 22446004
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MicroRNA-17-mediated down-regulation of apoptotic protease activating factor 1 attenuates apoptosome formation and subsequent apoptosis of cardiomyocytes.
    Song S; Seo HH; Lee SY; Lee CY; Lee J; Yoo KJ; Yoon C; Choi E; Hwang KC; Lee S
    Biochem Biophys Res Commun; 2015 Sep; 465(2):299-304. PubMed ID: 26265044
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Intracellular K(+) inhibits apoptosis by suppressing the Apaf-1 apoptosome formation and subsequent downstream pathways but not cytochrome c release.
    Karki P; Seong C; Kim JE; Hur K; Shin SY; Lee JS; Cho B; Park IS
    Cell Death Differ; 2007 Dec; 14(12):2068-75. PubMed ID: 17885667
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apaf-1: Regulation and function in cell death.
    Shakeri R; Kheirollahi A; Davoodi J
    Biochimie; 2017 Apr; 135():111-125. PubMed ID: 28192157
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Integrity of ATP binding site is essential for effective inhibition of the intrinsic apoptosis pathway by NAIP.
    Karimpour S; Davoodi J; Ghahremani MH
    Biochem Biophys Res Commun; 2011 Apr; 407(1):158-62. PubMed ID: 21371431
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Apoptosome structure, assembly, and procaspase activation.
    Yuan S; Akey CW
    Structure; 2013 Apr; 21(4):501-15. PubMed ID: 23561633
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1.
    Bao Q; Lu W; Rabinowitz JD; Shi Y
    Mol Cell; 2007 Jan; 25(2):181-92. PubMed ID: 17244527
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Optimal pathways for the assembly of the Apaf-1·cytochrome c complex into apoptosome.
    Qi H; Jiang Y; Yin Z; Jiang K; Li L; Shuai J
    Phys Chem Chem Phys; 2018 Jan; 20(3):1964-1973. PubMed ID: 29299551
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems.
    Noori AR; Hosseini ES; Nikkhah M; Hosseinkhani S
    Arch Biochem Biophys; 2018 Mar; 642():46-51. PubMed ID: 29410086
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme.
    Li Y; Zhou M; Hu Q; Bai XC; Huang W; Scheres SH; Shi Y
    Proc Natl Acad Sci U S A; 2017 Feb; 114(7):1542-1547. PubMed ID: 28143931
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Small molecule inhibitors of Apaf-1-related caspase- 3/-9 activation that control mitochondrial-dependent apoptosis.
    Malet G; Martín AG; Orzáez M; Vicent MJ; Masip I; Sanclimens G; Ferrer-Montiel A; Mingarro I; Messeguer A; Fearnhead HO; Pérez-Payá E
    Cell Death Differ; 2006 Sep; 13(9):1523-32. PubMed ID: 16341125
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.
    Noori AR; Tashakor A; Nikkhah M; Eriksson LA; Hosseinkhani S; Fearnhead HO
    Biochimie; 2021 Jan; 180():23-29. PubMed ID: 33132160
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vaccinia Virus Encodes a Novel Inhibitor of Apoptosis That Associates with the Apoptosome.
    Ryerson MR; Richards MM; Kvansakul M; Hawkins CJ; Shisler JL
    J Virol; 2017 Dec; 91(23):. PubMed ID: 28904196
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1.
    Manns J; Daubrawa M; Driessen S; Paasch F; Hoffmann N; Löffler A; Lauber K; Dieterle A; Alers S; Iftner T; Schulze-Osthoff K; Stork B; Wesselborg S
    FASEB J; 2011 Sep; 25(9):3250-61. PubMed ID: 21659556
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome.
    Su TW; Yang CY; Kao WP; Kuo BJ; Lin SM; Lin JY; Lo YC; Lin SC
    Structure; 2017 Mar; 25(3):407-420. PubMed ID: 28111022
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activation.
    Würstle ML; Rehm M
    J Biol Chem; 2014 Sep; 289(38):26277-26289. PubMed ID: 25107908
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3.
    Yuan S; Yu X; Asara JM; Heuser JE; Ludtke SJ; Akey CW
    Structure; 2011 Aug; 19(8):1084-96. PubMed ID: 21827945
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of translationally controlled tumor protein with Apaf-1 is involved in the development of chemoresistance in HeLa cells.
    Jung J; Kim HY; Maeng J; Kim M; Shin DH; Lee K
    BMC Cancer; 2014 Mar; 14():165. PubMed ID: 24606760
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.