80 related articles for article (PubMed ID: 24429221)
1. Characterising the plasma-target occupancy relationship of the neurokinin antagonist GSK1144814 with PET.
Ridler K; Gunn RN; Searle GE; Barletta J; Passchier J; Dixson L; Hallett WA; Ashworth S; Gray FA; Burgess C; Poggesi I; Bullman JN; Ratti E; Laruelle MA; Rabiner EA
J Psychopharmacol; 2014 Mar; 28(3):244-53. PubMed ID: 24429221
[TBL] [Abstract][Full Text] [Related]
2. Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant.
Bergström M; Hargreaves RJ; Burns HD; Goldberg MR; Sciberras D; Reines SA; Petty KJ; Ogren M; Antoni G; Långström B; Eskola O; Scheinin M; Solin O; Majumdar AK; Constanzer ML; Battisti WP; Bradstreet TE; Gargano C; Hietala J
Biol Psychiatry; 2004 May; 55(10):1007-12. PubMed ID: 15121485
[TBL] [Abstract][Full Text] [Related]
3. Quantification of central substance P receptor occupancy by aprepitant using small animal positron emission tomography.
Endo T; Saijo T; Haneda E; Maeda J; Tokunaga M; Zhang MR; Kannami A; Asai H; Suzuki M; Suhara T; Higuchi M
Int J Neuropsychopharmacol; 2014 Oct; 18(2):. PubMed ID: 25609595
[TBL] [Abstract][Full Text] [Related]
4. Rolapitant Absolute Bioavailability and PET Imaging Studies in Healthy Adult Volunteers.
Wang X; Zhang ZY; Powers D; Wang J; Lu S; Kansra V
Clin Pharmacol Ther; 2017 Aug; 102(2):332-339. PubMed ID: 28139838
[TBL] [Abstract][Full Text] [Related]
5. Pharmacokinetics and central nervous system effects of the novel dual NK1 /NK3 receptor antagonist GSK1144814 in alcohol-intoxicated volunteers.
te Beek ET; Hay JL; Bullman JN; Burgess C; Nahon KJ; Klaassen ES; Gray FA; van Gerven JM
Br J Clin Pharmacol; 2013 May; 75(5):1328-39. PubMed ID: 23067311
[TBL] [Abstract][Full Text] [Related]
6. Equivalent dynamic human brain NK1-receptor occupancy following single-dose i.v. fosaprepitant vs. oral aprepitant as assessed by PET imaging.
Van Laere K; De Hoon J; Bormans G; Koole M; Derdelinckx I; De Lepeleire I; Declercq R; Sanabria Bohorquez SM; Hamill T; Mozley PD; Tatosian D; Xie W; Liu Y; Liu F; Zappacosta P; Mahon C; Butterfield KL; Rosen LB; Murphy MG; Hargreaves RJ; Wagner JA; Shadle CR
Clin Pharmacol Ther; 2012 Aug; 92(2):243-50. PubMed ID: 22739139
[TBL] [Abstract][Full Text] [Related]
7. A pharmacokinetic PET study of NK₁ receptor occupancy.
Zamuner S; Rabiner EA; Fernandes SA; Bani M; Gunn RN; Gomeni R; Ratti E; Cunningham VJ
Eur J Nucl Med Mol Imaging; 2012 Feb; 39(2):226-35. PubMed ID: 21993526
[TBL] [Abstract][Full Text] [Related]
8. Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: dopamine D2, serotonin 2A and NK-1 receptors as examples.
Chernet E; Martin LJ; Li D; Need AB; Barth VN; Rash KS; Phebus LA
Life Sci; 2005 Dec; 78(4):340-6. PubMed ID: 16139310
[TBL] [Abstract][Full Text] [Related]
9. Imaging substance P receptors (NK1) in the living human brain using positron emission tomography.
Hargreaves R
J Clin Psychiatry; 2002; 63 Suppl 11():18-24. PubMed ID: 12562139
[TBL] [Abstract][Full Text] [Related]
10. Development of the 2nd generation neurokinin-1 receptor antagonist LY686017 for social anxiety disorder.
Tauscher J; Kielbasa W; Iyengar S; Vandenhende F; Peng X; Mozley D; Gehlert DR; Marek G
Eur Neuropsychopharmacol; 2010 Feb; 20(2):80-7. PubMed ID: 20018493
[TBL] [Abstract][Full Text] [Related]
11. NK1 receptor antagonists for depression: Why a validated concept was abandoned.
Rupniak NMJ; Kramer MS
J Affect Disord; 2017 Dec; 223():121-125. PubMed ID: 28753469
[TBL] [Abstract][Full Text] [Related]
12. In vitro and ex vivo autoradiography of the NK-1 antagonist [³H]-LY686017 in Guinea pig brain.
Gackenheimer SL; Gehlert DR
Neuropeptides; 2011 Apr; 45(2):157-64. PubMed ID: 21295853
[TBL] [Abstract][Full Text] [Related]
13. Contribution of SPECT measurements of D2 and 5-HT2A occupancy to the clinical development of the antipsychotic SB-773812.
Catafau AM; Bullich S; Nucci G; Burgess C; Gray F; Merlo-Pich E;
J Nucl Med; 2011 Apr; 52(4):526-34. PubMed ID: 21421726
[TBL] [Abstract][Full Text] [Related]
14. Are biological actions of neurokinin A in the adult brain mediated by a cross-talk between the NK1 and NK2 receptors?
Tauer U; Zhao Y; Hunt SP; Culman J
Neuropharmacology; 2012 Nov; 63(6):958-65. PubMed ID: 22771977
[TBL] [Abstract][Full Text] [Related]
15. Visualization and quantification of neurokinin-1 (NK1) receptors in the human brain.
Hietala J; Nyman MJ; Eskola O; Laakso A; Grönroos T; Oikonen V; Bergman J; Haaparanta M; Forsback S; Marjamäki P; Lehikoinen P; Goldberg M; Burns D; Hamill T; Eng WS; Coimbra A; Hargreaves R; Solin O
Mol Imaging Biol; 2005; 7(4):262-72. PubMed ID: 16155744
[TBL] [Abstract][Full Text] [Related]
16. Efficacy and safety of repeated dosing of netupitant, a neurokinin-1 receptor antagonist, in treating overactive bladder.
Haab F; Braticevici B; Krivoborodov G; Palmas M; Zufferli Russo M; Pietra C
Neurourol Urodyn; 2014 Mar; 33(3):335-40. PubMed ID: 23765630
[TBL] [Abstract][Full Text] [Related]
17. The neurokinin 1 receptor regulates peritoneal fibrinolytic activity and postoperative adhesion formation.
Cassidy MR; Sheldon HK; Gainsbury ML; Gillespie E; Kosaka H; Heydrick S; Stucchi AF
J Surg Res; 2014 Sep; 191(1):12-8. PubMed ID: 24836694
[TBL] [Abstract][Full Text] [Related]
18. Modeling of brain D2 receptor occupancy-plasma concentration relationships with a novel antipsychotic, YKP1358, using serial PET scans in healthy volunteers.
Lim KS; Kwon JS; Jang IJ; Jeong JM; Lee JS; Kim HW; Kang WJ; Kim JR; Cho JY; Kim E; Yoo SY; Shin SG; Yu KS
Clin Pharmacol Ther; 2007 Feb; 81(2):252-8. PubMed ID: 17259948
[TBL] [Abstract][Full Text] [Related]
19. Pharmacology of MEN 11467: a potent new selective and orally- effective peptidomimetic tachykinin NK(1) receptor antagonist.
Cirillo R; Astolfi M; Conte B; Lopez G; Parlani M; Sacco G; Terracciano R; Fincham CI; Sisto A; Evangelista S; Maggi CA; Manzini S
Neuropeptides; 2001; 35(3-4):137-47. PubMed ID: 11884203
[TBL] [Abstract][Full Text] [Related]
20. Role of nitric oxide and septide-insensitive NK(1) receptors in bronchoconstriction induced by aerosolised neurokinin A in guinea-pigs.
Ricciardolo FL; Trevisani M; Geppetti P; Nadel JA; Amadesi S; Bertrand C
Br J Pharmacol; 2000 Mar; 129(5):915-20. PubMed ID: 10696090
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
