BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

361 related articles for article (PubMed ID: 24429402)

  • 1. Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis.
    Chow BS; Kocan M; Bosnyak S; Sarwar M; Wigg B; Jones ES; Widdop RE; Summers RJ; Bathgate RA; Hewitson TD; Samuel CS
    Kidney Int; 2014 Jul; 86(1):75-85. PubMed ID: 24429402
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The anti-fibrotic actions of relaxin are mediated through AT
    Wang C; Pinar AA; Widdop RE; Hossain MA; Bathgate RAD; Denton KM; Kemp-Harper BK; Samuel CS
    FASEB J; 2020 Jun; 34(6):8217-8233. PubMed ID: 32297670
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis.
    Chow BSM; Kocan M; Shen M; Wang Y; Han L; Chew JY; Wang C; Bosnyak S; Mirabito-Colafella KM; Barsha G; Wigg B; Johnstone EKM; Hossain MA; Pfleger KDG; Denton KM; Widdop RE; Summers RJ; Bathgate RAD; Hewitson TD; Samuel CS
    J Am Soc Nephrol; 2019 Nov; 30(11):2191-2207. PubMed ID: 31511361
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New targets for renal interstitial fibrosis: relaxin family peptide receptor 1-angiotensin type 2 receptor heterodimers.
    Sasser JM
    Kidney Int; 2014 Jul; 86(1):9-10. PubMed ID: 24978374
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Relaxin signals through a RXFP1-pERK-nNOS-NO-cGMP-dependent pathway to up-regulate matrix metalloproteinases: the additional involvement of iNOS.
    Chow BS; Chew EG; Zhao C; Bathgate RA; Hewitson TD; Samuel CS
    PLoS One; 2012; 7(8):e42714. PubMed ID: 22936987
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2.
    Mookerjee I; Hewitson TD; Halls ML; Summers RJ; Mathai ML; Bathgate RA; Tregear GW; Samuel CS
    FASEB J; 2009 Apr; 23(4):1219-29. PubMed ID: 19073841
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.
    Heeg MH; Koziolek MJ; Vasko R; Schaefer L; Sharma K; Müller GA; Strutz F
    Kidney Int; 2005 Jul; 68(1):96-109. PubMed ID: 15954899
    [TBL] [Abstract][Full Text] [Related]  

  • 8. H3 relaxin demonstrates antifibrotic properties via the RXFP1 receptor.
    Hossain MA; Man BC; Zhao C; Xu Q; Du XJ; Wade JD; Samuel CS
    Biochemistry; 2011 Mar; 50(8):1368-75. PubMed ID: 21229994
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The emerging role of relaxin as a novel therapeutic pathway in the treatment of chronic kidney disease.
    Sasser JM
    Am J Physiol Regul Integr Comp Physiol; 2013 Sep; 305(6):R559-65. PubMed ID: 23883673
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mesangial cells cultured from pregnant rats display reduced reactivity to angiotensin II: the role of relaxin, nitric oxide and AT2 receptor.
    Carvalho LN; Cristovam PC; Passos CS; Boim MA
    Cell Physiol Biochem; 2012; 30(6):1456-64. PubMed ID: 23207895
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduced sensitivity of the renal vasculature to angiotensin II in young rats: the role of the angiotensin type 2 receptor.
    Brown RD; Hilliard LM; Mirabito KM; Wirth LC; Moritz KM; Evans RG; Denton KM
    Pediatr Res; 2014 Nov; 76(5):448-52. PubMed ID: 25119338
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Angiotensin II Type 2 Receptor and Receptor Mas Are Colocalized and Functionally Interdependent in Obese Zucker Rat Kidney.
    Patel SN; Ali Q; Samuel P; Steckelings UM; Hussain T
    Hypertension; 2017 Oct; 70(4):831-838. PubMed ID: 28827476
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of Mas receptor antagonist (A779) on pressure diuresis and natriuresis and renal blood flow in the absence of angiotensin II receptors type 1 and 2 in female and male rats.
    Mansoori A; Oryan S; Nematbakhsh M
    J Physiol Pharmacol; 2014 Oct; 65(5):633-9. PubMed ID: 25371522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prevention of bleomycin-induced pulmonary fibrosis by a novel antifibrotic peptide with relaxin-like activity.
    Pini A; Shemesh R; Samuel CS; Bathgate RA; Zauberman A; Hermesh C; Wool A; Bani D; Rotman G
    J Pharmacol Exp Ther; 2010 Dec; 335(3):589-99. PubMed ID: 20826567
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Angiotensin II Type 2 Receptor Decreases Transforming Growth Factor-β Type II Receptor Expression and Function in Human Renal Proximal Tubule Cells.
    Guo HL; Liao XH; Liu Q; Zhang L
    PLoS One; 2016; 11(2):e0148696. PubMed ID: 26867007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relaxin Attenuates Organ Fibrosis
    Barsha G; Walton SL; Kwok E; Mirabito Colafella KM; Pinar AA; Hilliard Krause LM; Gaspari TA; Widdop RE; Samuel CS; Denton KM
    Kidney360; 2021 Nov; 2(11):1781-1792. PubMed ID: 35373008
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibiting aerobic glycolysis suppresses renal interstitial fibroblast activation and renal fibrosis.
    Ding H; Jiang L; Xu J; Bai F; Zhou Y; Yuan Q; Luo J; Zen K; Yang J
    Am J Physiol Renal Physiol; 2017 Sep; 313(3):F561-F575. PubMed ID: 28228400
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists.
    Hu X; Myhr C; Huang Z; Xiao J; Barnaeva E; Ho BA; Agoulnik IU; Ferrer M; Marugan JJ; Southall N; Agoulnik AI
    Biochemistry; 2016 Mar; 55(12):1772-83. PubMed ID: 26866459
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chronic blockade of the AT2 receptor with PD123319 impairs insulin signaling in C57BL/6 mice.
    Muñoz MC; Burghi V; Miquet JG; Cervino IA; Quiroga DT; Mazziotta L; Dominici FP
    Peptides; 2017 Feb; 88():37-45. PubMed ID: 27979738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Receptor-independent modulation of TGF-β-induced pro-fibrotic pathways by relaxin-2 in human primary tubular epithelial cells.
    Grampp S; Goppelt-Struebe M
    Cell Tissue Res; 2018 Dec; 374(3):619-627. PubMed ID: 30078103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.