BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 24437676)

  • 1. Classification of hepatotoxicants using HepG2 cells: A proof of principle study.
    Van den Hof WF; Coonen ML; van Herwijnen M; Brauers K; Wodzig WK; van Delft JH; Kleinjans JC
    Chem Res Toxicol; 2014 Mar; 27(3):433-42. PubMed ID: 24437676
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
    Vatakuti S; Pennings JL; Gore E; Olinga P; Groothuis GM
    Chem Res Toxicol; 2016 Mar; 29(3):342-51. PubMed ID: 26881866
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acute hepatotoxicity: a predictive model based on focused illumina microarrays.
    Zidek N; Hellmann J; Kramer PJ; Hewitt PG
    Toxicol Sci; 2007 Sep; 99(1):289-302. PubMed ID: 17522070
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of potential genomic biomarkers of hepatotoxicity caused by reactive metabolites of N-methylformamide: Application of stable isotope labeled compounds in toxicogenomic studies.
    Mutlib A; Jiang P; Atherton J; Obert L; Kostrubsky S; Madore S; Nelson S
    Chem Res Toxicol; 2006 Oct; 19(10):1270-83. PubMed ID: 17040096
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Validation of gene expression profiles from cholestatic hepatotoxicants in vitro against human in vivo cholestasis.
    Van den Hof WFPM; Coonen MLJ; van Herwijnen M; Brauers K; Jennen D; Olde Damink SWM; Schaap FG; Kleinjans JCS
    Toxicol In Vitro; 2017 Oct; 44():322-329. PubMed ID: 28778767
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Toxicogenomics strategies for predicting drug toxicity.
    Martin R; Rose D; Yu K; Barros S
    Pharmacogenomics; 2006 Oct; 7(7):1003-16. PubMed ID: 17054411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray database.
    Rueda-Zárate HA; Imaz-Rosshandler I; Cárdenas-Ovando RA; Castillo-Fernández JE; Noguez-Monroy J; Rangel-Escareño C
    PLoS One; 2017; 12(4):e0176284. PubMed ID: 28448553
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro.
    Van den Hof WF; Ruiz-Aracama A; Van Summeren A; Jennen DG; Gaj S; Coonen ML; Brauers K; Wodzig WK; van Delft JH; Kleinjans JC
    Toxicol In Vitro; 2015 Apr; 29(3):489-501. PubMed ID: 25562108
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes.
    Grinberg M; Stöber RM; Albrecht W; Edlund K; Schug M; Godoy P; Cadenas C; Marchan R; Lampen A; Braeuning A; Buhrke T; Leist M; Oberemm A; Hellwig B; Kamp H; Gardner I; Escher S; Taboureau O; Aguayo-Orozco A; Sachinidis A; Ellinger-Ziegelbauer H; Rahnenführer J; Hengstler JG
    Arch Toxicol; 2018 Dec; 92(12):3517-3533. PubMed ID: 30511339
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach.
    Vatakuti S; Olinga P; Pennings JLA; Groothuis GMM
    Arch Toxicol; 2017 Mar; 91(3):1401-1412. PubMed ID: 27344345
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A gene expression signature for oxidant stress/reactive metabolites in rat liver.
    McMillian M; Nie AY; Parker JB; Leone A; Bryant S; Kemmerer M; Herlich J; Liu Y; Yieh L; Bittner A; Liu X; Wan J; Johnson MD
    Biochem Pharmacol; 2004 Dec; 68(11):2249-61. PubMed ID: 15498515
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Determination of phospholipidosis potential based on gene expression analysis in HepG2 cells.
    Atienzar F; Gerets H; Dufrane S; Tilmant K; Cornet M; Dhalluin S; Ruty B; Rose G; Canning M
    Toxicol Sci; 2007 Mar; 96(1):101-14. PubMed ID: 17175557
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity.
    Elferink MG; Olinga P; Draaisma AL; Merema MT; Bauerschmidt S; Polman J; Schoonen WG; Groothuis GM
    Toxicol Appl Pharmacol; 2008 Jun; 229(3):300-9. PubMed ID: 18346771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression profile of liver genes in response to hepatotoxicants identified using a SAGE-based customized DNA microarray system.
    Inadera H; Tachibana S; Takasaki I; Tabuchi Y; Matsushima K; Uchida M; Shimomura A
    Toxicol Lett; 2008 Feb; 177(1):20-30. PubMed ID: 18243596
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.
    Tolosa L; Gómez-Lechón MJ; Pérez-Cataldo G; Castell JV; Donato MT
    Arch Toxicol; 2013 Jun; 87(6):1115-27. PubMed ID: 23397584
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans.
    Driessen M; Kienhuis AS; Vitins AP; Pennings JL; Pronk TE; van den Brandhof EJ; Roodbergen M; van de Water B; van der Ven LT
    Toxicol Lett; 2014 Oct; 230(1):48-56. PubMed ID: 25064622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Baseline and genotoxic compound induced gene expression profiles in HepG2 and HepaRG compared to primary human hepatocytes.
    Jetten MJ; Kleinjans JC; Claessen SM; Chesné C; van Delft JH
    Toxicol In Vitro; 2013 Oct; 27(7):2031-40. PubMed ID: 23911569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Validation of putative genomic biomarkers of nephrotoxicity in rats.
    Wang EJ; Snyder RD; Fielden MR; Smith RJ; Gu YZ
    Toxicology; 2008 Apr; 246(2-3):91-100. PubMed ID: 18289764
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of an approach for ab initio estimation of compound-induced liver injury based on global gene transcriptional profiles.
    Dai X; He YD; Dai H; Lum PY; Roberts CJ; Waring JF; Ulrich RG
    Genome Inform; 2006; 17(2):77-88. PubMed ID: 17503381
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Class prediction in toxicogenomics.
    Raghavan N; Amaratunga D; Nie AY; McMillian M
    J Biopharm Stat; 2005; 15(2):327-41. PubMed ID: 15796298
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.