BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 24438557)

  • 1. TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells.
    Vo Nguyen TT; Watanabe Y; Shiba A; Noguchi M; Itoh S; Kato M
    Cancer Sci; 2014 Mar; 105(3):334-41. PubMed ID: 24438557
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling.
    Watanabe Y; Itoh S; Goto T; Ohnishi E; Inamitsu M; Itoh F; Satoh K; Wiercinska E; Yang W; Shi L; Tanaka A; Nakano N; Mommaas AM; Shibuya H; Ten Dijke P; Kato M
    Mol Cell; 2010 Jan; 37(1):123-34. PubMed ID: 20129061
    [TBL] [Abstract][Full Text] [Related]  

  • 3. C18 ORF1, a novel negative regulator of transforming growth factor-β signaling.
    Nakano N; Maeyama K; Sakata N; Itoh F; Akatsu R; Nakata M; Katsu Y; Ikeno S; Togawa Y; Vo Nguyen TT; Watanabe Y; Kato M; Itoh S
    J Biol Chem; 2014 May; 289(18):12680-92. PubMed ID: 24627487
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PMEPA1/TMEPAI isoforms function via its PY and Smad-interaction motifs for tumorigenic activities of breast cancer cells.
    Puteri MU; Watanabe Y; Wardhani BWK; Amalia R; Abdelaziz M; Kato M
    Genes Cells; 2020 Jun; 25(6):375-390. PubMed ID: 32181976
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cooperative induction of transmembrane prostate androgen induced protein TMEPAI/PMEPA1 by transforming growth factor-β and epidermal growth factor signaling.
    Azami S; Vo Nguyen TT; Watanabe Y; Kato M
    Biochem Biophys Res Commun; 2015 Jan; 456(2):580-5. PubMed ID: 25482449
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TMEPAI inhibits TGF-β signaling by promoting lysosome degradation of TGF-β receptor and contributes to lung cancer development.
    Bai X; Jing L; Li Y; Li Y; Luo S; Wang S; Zhou J; Liu Z; Diao A
    Cell Signal; 2014 Sep; 26(9):2030-9. PubMed ID: 24933703
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TGF-β induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer.
    Singha PK; Pandeswara S; Geng H; Lan R; Venkatachalam MA; Saikumar P
    Genes Cancer; 2014 Sep; 5(9-10):320-36. PubMed ID: 25352949
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer.
    Singha PK; Yeh IT; Venkatachalam MA; Saikumar P
    Cancer Res; 2010 Aug; 70(15):6377-83. PubMed ID: 20610632
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PDZK1-interacting protein 1 (PDZK1IP1) traps Smad4 protein and suppresses transforming growth factor-β (TGF-β) signaling.
    Ikeno S; Nakano N; Sano K; Minowa T; Sato W; Akatsu R; Sakata N; Hanagata N; Fujii M; Itoh F; Itoh S
    J Biol Chem; 2019 Mar; 294(13):4966-4980. PubMed ID: 30718277
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways.
    Hu Y; He K; Wang D; Yuan X; Liu Y; Ji H; Song J
    Carcinogenesis; 2013 Aug; 34(8):1764-72. PubMed ID: 23615405
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dissecting the role of TGF-beta type I receptor/ALK5 in pancreatic ductal adenocarcinoma: Smad activation is crucial for both the tumor suppressive and prometastatic function.
    Schniewind B; Groth S; Sebens Müerköster S; Sipos B; Schäfer H; Kalthoff H; Fändrich F; Ungefroren H
    Oncogene; 2007 Jul; 26(33):4850-62. PubMed ID: 17297450
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer.
    Singha PK; Pandeswara S; Geng H; Lan R; Venkatachalam MA; Dobi A; Srivastava S; Saikumar P
    Genes Cancer; 2019; 10(5-6):134-149. PubMed ID: 31798766
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene.
    Nakano N; Itoh S; Watanabe Y; Maeyama K; Itoh F; Kato M
    J Biol Chem; 2010 Dec; 285(49):38023-33. PubMed ID: 20889500
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TMEPAI/PMEPA1 inhibits Wnt signaling by regulating β-catenin stability and nuclear accumulation in triple negative breast cancer cells.
    Amalia R; Abdelaziz M; Puteri MU; Hwang J; Anwar F; Watanabe Y; Kato M
    Cell Signal; 2019 Jul; 59():24-33. PubMed ID: 30890370
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TGF-β/SMAD3 Pathway Stimulates Sphingosine-1 Phosphate Receptor 3 Expression: IMPLICATION OF SPHINGOSINE-1 PHOSPHATE RECEPTOR 3 IN LUNG ADENOCARCINOMA PROGRESSION.
    Zhao J; Liu J; Lee JF; Zhang W; Kandouz M; VanHecke GC; Chen S; Ahn YH; Lonardo F; Lee MJ
    J Biol Chem; 2016 Dec; 291(53):27343-27353. PubMed ID: 27856637
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PMEPA1/TMEPAI Is a Unique Tumorigenic Activator of AKT Promoting Proteasomal Degradation of PHLPP1 in Triple-Negative Breast Cancer Cells.
    Haque MA; Abdelaziz M; Puteri MU; Vo Nguyen TT; Kudo K; Watanabe Y; Kato M
    Cancers (Basel); 2021 Sep; 13(19):. PubMed ID: 34638419
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transforming Growth Factor-β Promotes Liver Tumorigenesis in Mice via Up-regulation of Snail.
    Moon H; Ju HL; Chung SI; Cho KJ; Eun JW; Nam SW; Han KH; Calvisi DF; Ro SW
    Gastroenterology; 2017 Nov; 153(5):1378-1391.e6. PubMed ID: 28734833
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells.
    Chen CL; Tsukamoto H; Liu JC; Kashiwabara C; Feldman D; Sher L; Dooley S; French SW; Mishra L; Petrovic L; Jeong JH; Machida K
    J Clin Invest; 2013 Jul; 123(7):2832-49. PubMed ID: 23921128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β).
    Lin S; Yu L; Yang J; Liu Z; Karia B; Bishop AJR; Jackson J; Lozano G; Copland JA; Mu X; Sun B; Sun LZ
    J Biol Chem; 2011 Dec; 286(51):44023-44034. PubMed ID: 22039050
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of transforming growth factor beta (TGF-beta) receptor on lung carcinogenesis.
    Park C; Kim WS; Choi Y; Kim H; Park K
    Lung Cancer; 2002 Nov; 38(2):143-7. PubMed ID: 12399125
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.