These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

389 related articles for article (PubMed ID: 24439375)

  • 21. Functional analysis of proposed substrate-binding residues of Hsp104.
    Howard MK; Sohn BS; von Borcke J; Xu A; Jackrel ME
    PLoS One; 2020; 15(3):e0230198. PubMed ID: 32155221
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma.
    Ryan JJ; Sprunger ML; Holthaus K; Shorter J; Jackrel ME
    J Biol Chem; 2019 Jul; 294(29):11286-11296. PubMed ID: 31171724
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease.
    Lo Bianco C; Shorter J; Régulier E; Lashuel H; Iwatsubo T; Lindquist S; Aebischer P
    J Clin Invest; 2008 Sep; 118(9):3087-97. PubMed ID: 18704197
    [TBL] [Abstract][Full Text] [Related]  

  • 24. N-terminal domain of yeast Hsp104 chaperone is dispensable for thermotolerance and prion propagation but necessary for curing prions by Hsp104 overexpression.
    Hung GC; Masison DC
    Genetics; 2006 Jun; 173(2):611-20. PubMed ID: 16582428
    [TBL] [Abstract][Full Text] [Related]  

  • 25. AAA+ Protein-Based Technologies to Counter Neurodegenerative Disease.
    March ZM; Mack KL; Shorter J
    Biophys J; 2019 Apr; 116(8):1380-1385. PubMed ID: 30952364
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structure and function of the molecular chaperone Hsp104 from yeast.
    Grimminger-Marquardt V; Lashuel HA
    Biopolymers; 2010 Mar; 93(3):252-76. PubMed ID: 19768774
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events.
    Michalska K; Zhang K; March ZM; Hatzos-Skintges C; Pintilie G; Bigelow L; Castellano LM; Miles LJ; Jackrel ME; Chuang E; Jedrzejczak R; Shorter J; Chiu W; Joachimiak A
    Structure; 2019 Mar; 27(3):449-463.e7. PubMed ID: 30595457
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Bacterial and Yeast AAA+ Disaggregases ClpB and Hsp104 Operate through Conserved Mechanism Involving Cooperation with Hsp70.
    Kummer E; Szlachcic A; Franke KB; Ungelenk S; Bukau B; Mogk A
    J Mol Biol; 2016 Oct; 428(21):4378-4391. PubMed ID: 27616763
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Structural determinants for protein unfolding and translocation by the Hsp104 protein disaggregase.
    Lee J; Sung N; Yeo L; Chang C; Lee S; Tsai FTF
    Biosci Rep; 2017 Dec; 37(6):. PubMed ID: 29175998
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Designer protein disaggregases to counter neurodegenerative disease.
    Shorter J
    Curr Opin Genet Dev; 2017 Jun; 44():1-8. PubMed ID: 28208059
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation.
    Sweeny EA; Jackrel ME; Go MS; Sochor MA; Razzo BM; DeSantis ME; Gupta K; Shorter J
    Mol Cell; 2015 Mar; 57(5):836-849. PubMed ID: 25620563
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Evidence for an unfolding/threading mechanism for protein disaggregation by Saccharomyces cerevisiae Hsp104.
    Lum R; Tkach JM; Vierling E; Glover JR
    J Biol Chem; 2004 Jul; 279(28):29139-46. PubMed ID: 15128736
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.
    Bosco DA; LaVoie MJ; Petsko GA; Ringe D
    Cold Spring Harb Perspect Biol; 2011 Oct; 3(10):a007500. PubMed ID: 21844169
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation.
    Miot M; Reidy M; Doyle SM; Hoskins JR; Johnston DM; Genest O; Vitery MC; Masison DC; Wickner S
    Proc Natl Acad Sci U S A; 2011 Apr; 108(17):6915-20. PubMed ID: 21474779
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases.
    Durie CL; Lin J; Scull NW; Mack KL; Jackrel ME; Sweeny EA; Castellano LM; Shorter J; Lucius AL
    Biophys J; 2019 May; 116(10):1856-1872. PubMed ID: 31027887
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The M-domain controls Hsp104 protein remodeling activity in an Hsp70/Hsp40-dependent manner.
    Sielaff B; Tsai FT
    J Mol Biol; 2010 Sep; 402(1):30-7. PubMed ID: 20654624
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Expanding role of molecular chaperones in regulating α-synuclein misfolding; implications in Parkinson's disease.
    Sharma SK; Priya S
    Cell Mol Life Sci; 2017 Feb; 74(4):617-629. PubMed ID: 27522545
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Regulation of the Hsp104 middle domain activity is critical for yeast prion propagation.
    Dulle JE; Stein KC; True HL
    PLoS One; 2014; 9(1):e87521. PubMed ID: 24466354
    [TBL] [Abstract][Full Text] [Related]  

  • 39. CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation.
    Lee S; Sielaff B; Lee J; Tsai FT
    Proc Natl Acad Sci U S A; 2010 May; 107(18):8135-40. PubMed ID: 20404203
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Analysis of the AAA sensor-2 motif in the C-terminal ATPase domain of Hsp104 with a site-specific fluorescent probe of nucleotide binding.
    Hattendorf DA; Lindquist SL
    Proc Natl Acad Sci U S A; 2002 Mar; 99(5):2732-7. PubMed ID: 11867765
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 20.