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2. Prolyl-peptidyl isomerase, Pin1, phosphorylation is compromised in association with the expression of the HFE polymorphic allele, H63D. Hall EC; Lee SY; Simmons Z; Neely EB; Nandar W; Connor JR Biochim Biophys Acta; 2010 Apr; 1802(4):389-95. PubMed ID: 20060900 [TBL] [Abstract][Full Text] [Related]
3. The H63D HFE gene variant promotes activation of the intrinsic apoptotic pathway via mitochondria dysfunction following β-amyloid peptide exposure. Mairuae N; Hall Ii EC; Cheepsunthorn P; Lee SY; Connor JR J Neurosci Res; 2010 Nov; 88(14):3079-89. PubMed ID: 20734416 [TBL] [Abstract][Full Text] [Related]
4. Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis. Tomatsu S; Orii KO; Fleming RE; Holden CC; Waheed A; Britton RS; Gutierrez MA; Velez-Castrillon S; Bacon BR; Sly WS Proc Natl Acad Sci U S A; 2003 Dec; 100(26):15788-93. PubMed ID: 14673107 [TBL] [Abstract][Full Text] [Related]
5. Evaluation of HFE (hemochromatosis) mutations as genetic modifiers in sporadic AD and MCI. Berlin D; Chong G; Chertkow H; Bergman H; Phillips NA; Schipper HM Neurobiol Aging; 2004 Apr; 25(4):465-74. PubMed ID: 15013567 [TBL] [Abstract][Full Text] [Related]
6. The effects of okra (Abelmoschus esculentus Linn.) on the cellular events associated with Alzheimer's disease in a stably expressed HFE neuroblastoma SH-SY5Y cell line. Mairuae N; Connor JR; Lee SY; Cheepsunthorn P; Tongjaroenbuangam W Neurosci Lett; 2015 Aug; 603():6-11. PubMed ID: 26170247 [TBL] [Abstract][Full Text] [Related]
7. A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice. Nandar W; Neely EB; Unger E; Connor JR Biochim Biophys Acta; 2013 Jun; 1832(6):729-41. PubMed ID: 23429074 [TBL] [Abstract][Full Text] [Related]
8. Risk factors for development of dementia in a unique six-year cohort study. I. An exploratory, pilot study of involvement of the E4 allele of apolipoprotein E, mutations of the hemochromatosis-HFE gene, type 2 diabetes, and stroke. Percy M; Somerville MJ; Hicks M; Garcia A; Colelli T; Wright E; Kitaygorodsky J; Jiang A; Ho V; Parpia A; Wong MK J Alzheimers Dis; 2014; 38(4):907-22. PubMed ID: 24081379 [TBL] [Abstract][Full Text] [Related]
9. Reduced white matter MRI transverse relaxation rate in cognitively normal H63D-HFE human carriers and H67D-HFE mice. Meadowcroft MD; Wang J; Purnell CJ; Peters DG; Eslinger PJ; Neely EB; Gill DJ; Vasavada M; Ali-Rahmani F; Yang QX; Connor JR Brain Imaging Behav; 2016 Dec; 10(4):1231-1242. PubMed ID: 26660104 [TBL] [Abstract][Full Text] [Related]
10. Involvement of ApoE E4 and H63D in sporadic Alzheimer's disease in a folate-supplemented Ontario population. Percy M; Moalem S; Garcia A; Somerville MJ; Hicks M; Andrews D; Azad A; Schwarz P; Beheshti Zavareh R; Birkan R; Choo C; Chow V; Dhaliwal S; Duda V; Kupferschmidt AL; Lam K; Lightman D; Machalek K; Mar W; Nguyen F; Rytwinski PJ; Svara E; Tran M; Wheeler K; Yeung L; Zanibbi K; Zener R; Ziraldo M; Freedman M J Alzheimers Dis; 2008 May; 14(1):69-84. PubMed ID: 18525129 [TBL] [Abstract][Full Text] [Related]
11. Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residues. Hall EC; Lee SY; Mairuae N; Simmons Z; Connor JR Neurobiol Aging; 2011 Aug; 32(8):1409-19. PubMed ID: 19775775 [TBL] [Abstract][Full Text] [Related]
12. Mutant HFE H63D protein is associated with prolonged endoplasmic reticulum stress and increased neuronal vulnerability. Liu Y; Lee SY; Neely E; Nandar W; Moyo M; Simmons Z; Connor JR J Biol Chem; 2011 Apr; 286(15):13161-70. PubMed ID: 21349849 [TBL] [Abstract][Full Text] [Related]
13. Association between the HFE mutations and unsuccessful ageing: a study in Alzheimer's disease patients from Northern Italy. Candore G; Licastro F; Chiappelli M; Franceschi C; Lio D; Rita Balistreri C; Piazza G; Colonna-Romano G; Grimaldi LM; Caruso C Mech Ageing Dev; 2003 Apr; 124(4):525-8. PubMed ID: 12714262 [TBL] [Abstract][Full Text] [Related]
14. Mutations of the HFE gene among Turkish hereditary hemochromatosis patients. Simsek H; Balaban YH; Yilmaz E; Sumer H; Buyukasik Y; Cengiz C; Ozcebe O; Hascelik G; Tatar G Ann Hematol; 2005 Oct; 84(10):646-9. PubMed ID: 15871018 [TBL] [Abstract][Full Text] [Related]
15. The hemochromatosis gene affects the age of onset of sporadic Alzheimer's disease. Sampietro M; Caputo L; Casatta A; Meregalli M; Pellagatti A; Tagliabue J; Annoni G; Vergani C Neurobiol Aging; 2001; 22(4):563-8. PubMed ID: 11445256 [TBL] [Abstract][Full Text] [Related]
16. Effect of HFE variants on sphingolipid expression by SH-SY5Y human neuroblastoma cells. Ali-Rahmani F; Hengst JA; Connor JR; Schengrund CL Neurochem Res; 2011 Sep; 36(9):1687-96. PubMed ID: 21243428 [TBL] [Abstract][Full Text] [Related]
17. Iron genes, iron load and risk of Alzheimer's disease. Lehmann DJ; Worwood M; Ellis R; Wimhurst VL; Merryweather-Clarke AT; Warden DR; Smith AD; Robson KJ J Med Genet; 2006 Oct; 43(10):e52. PubMed ID: 17047092 [TBL] [Abstract][Full Text] [Related]
18. Changes in brain transcripts related to Alzheimer's disease in a model of HFE hemochromatosis are not consistent with increased Alzheimer's disease risk. Johnstone DM; Graham RM; Trinder D; Riveros C; Olynyk JK; Scott RJ; Moscato P; Milward EA J Alzheimers Dis; 2012; 30(4):791-803. PubMed ID: 22466002 [TBL] [Abstract][Full Text] [Related]
19. Prevalence of C282Y, H63D, and S65C mutations in hereditary HFE-hemochromatosis gene in Lithuanian population. Kucinskas L; Juzenas S; Sventoraityte J; Cedaviciute R; Vitkauskiene A; Kalibatas V; Kondrackiene J; Kupcinskas L Ann Hematol; 2012 Apr; 91(4):491-5. PubMed ID: 21947086 [TBL] [Abstract][Full Text] [Related]
20. A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism. Njajou OT; Houwing-Duistermaat JJ; Osborne RH; Vaessen N; Vergeer J; Heeringa J; Pols HA; Hofman A; van Duijn CM Eur J Hum Genet; 2003 Mar; 11(3):225-31. PubMed ID: 12673276 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]