BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

373 related articles for article (PubMed ID: 24447464)

  • 1. Identification of novel 11β-HSD1 inhibitors by combined ligand- and structure-based virtual screening.
    Lagos CF; Vecchiola A; Allende F; Fuentes CA; Tichauer JE; Valdivia C; Solari S; Campino C; Tapia-Castillo A; Baudrand R; Villarroel P; Cifuentes M; Owen GI; Carvajal CA; Fardella CE
    Mol Cell Endocrinol; 2014 Mar; 384(1-2):71-82. PubMed ID: 24447464
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of novel inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 by docking and pharmacophore modeling.
    Yang H; Dou W; Lou J; Leng Y; Shen J
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1340-5. PubMed ID: 18242087
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening.
    Schuster D; Maurer EM; Laggner C; Nashev LG; Wilckens T; Langer T; Odermatt A
    J Med Chem; 2006 Jun; 49(12):3454-66. PubMed ID: 16759088
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors with oleanan and ursan scaffolds.
    Blum A; Favia AD; Maser E
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):132-6. PubMed ID: 18822345
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening.
    Xia G; Xue M; Liu L; Yu J; Liu H; Li P; Wang J; Li Y; Xiong B; Shen J
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5739-44. PubMed ID: 21873057
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Endogenous inhibitors (GALFs) of 11beta-hydroxysteroid dehydrogenase isoforms 1 and 2: derivatives of adrenally produced corticosterone and cortisol.
    Morris DJ; Latif SA; Hardy MP; Brem AS
    J Steroid Biochem Mol Biol; 2007 May; 104(3-5):161-8. PubMed ID: 17459698
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in patients with chronic rhinosinusitis and their possible contribution to local glucocorticoid activation in sinus mucosa.
    Jun YJ; Park SJ; Kim TH; Lee SH; Lee KJ; Hwang SM; Lee SH
    J Allergy Clin Immunol; 2014 Oct; 134(4):926-934.e6. PubMed ID: 24810847
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice.
    Park JS; Rhee SD; Jung WH; Kang NS; Kim HY; Kang SK; Ahn JH; Kim KY
    Eur J Pharmacol; 2012 Sep; 691(1-3):19-27. PubMed ID: 22760069
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 17Beta-estradiol inhibits 11beta-hydroxysteroid dehydrogenase type 1 activity in rodent adipocytes.
    Tagawa N; Yuda R; Kubota S; Wakabayashi M; Yamaguchi Y; Kiyonaga D; Mori N; Minamitani E; Masuzaki H; Kobayashi Y
    J Endocrinol; 2009 Jul; 202(1):131-9. PubMed ID: 19380458
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential expression of 11β-hydroxysteroid dehydrogenase type 1 and 2 in mild and moderate/severe persistent allergic nasal mucosa and regulation of their expression by Th2 cytokines: asthma and rhinitis.
    Jun YJ; Park SJ; Hwang JW; Kim TH; Jung KJ; Jung JY; Hwang GH; Lee SH; Lee SH
    Clin Exp Allergy; 2014 Feb; 44(2):197-211. PubMed ID: 24447082
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery and structure-activity relationships of pentanedioic acid diamides as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
    Roche D; Carniato D; Leriche C; Lepifre F; Christmann-Franck S; Graedler U; Charon C; Bozec S; Doare L; Schmidlin F; Lecomte M; Valeur E
    Bioorg Med Chem Lett; 2009 May; 19(10):2674-8. PubMed ID: 19395260
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of novel 3-amino and 29-hydroxamic acid derivatives of glycyrrhetinic acid as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors.
    Stanetty C; Czollner L; Koller I; Shah P; Gaware R; Cunha TD; Odermatt A; Jordis U; Kosma P; Classen-Houben D
    Bioorg Med Chem; 2010 Nov; 18(21):7522-41. PubMed ID: 20851614
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel non-steroidal inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Vicker N; Su X; Ganeshapillai D; Smith A; Purohit A; Reed MJ; Potter BV
    J Steroid Biochem Mol Biol; 2007 May; 104(3-5):123-9. PubMed ID: 17482805
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.
    Webster SP; Ward P; Binnie M; Craigie E; McConnell KM; Sooy K; Vinter A; Seckl JR; Walker BR
    Bioorg Med Chem Lett; 2007 May; 17(10):2838-43. PubMed ID: 17350260
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Altered activity of 11beta-hydroxysteroid dehydrogenase types 1 and 2 in skeletal muscle confers metabolic protection in subjects with type 2 diabetes.
    Jang C; Obeyesekere VR; Dilley RJ; Krozowski Z; Inder WJ; Alford FP
    J Clin Endocrinol Metab; 2007 Aug; 92(8):3314-20. PubMed ID: 17519316
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Tu H; Powers JP; Liu J; Ursu S; Sudom A; Yan X; Xu H; Meininger D; Degraffenreid M; He X; Jaen JC; Sun D; Labelle M; Yamamoto H; Shan B; Walker NP; Wang Z
    Bioorg Med Chem; 2008 Oct; 16(19):8922-31. PubMed ID: 18789704
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Su X; Vicker N; Trusselle M; Halem H; Culler MD; Potter BV
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):169-73. PubMed ID: 18775471
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel highly potent and selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, UI-1499.
    Byun SY; Shin YJ; Nam KY; Hong SP; Ahn SK
    Life Sci; 2015 Jan; 120():1-7. PubMed ID: 25447448
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Benzothiazole derivatives as novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Su X; Vicker N; Ganeshapillai D; Smith A; Purohit A; Reed MJ; Potter BV
    Mol Cell Endocrinol; 2006 Mar; 248(1-2):214-7. PubMed ID: 16325333
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 11beta-hydroxysteroid dehydrogenase type 1 inhibitors as promising therapeutic drugs for diabetes: status and development.
    Ge R; Huang Y; Liang G; Li X
    Curr Med Chem; 2010; 17(5):412-22. PubMed ID: 20015040
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.