163 related articles for article (PubMed ID: 24451134)
1. Genetic deletion of Rheb1 in the brain reduces food intake and causes hypoglycemia with altered peripheral metabolism.
Yang W; Jiang W; Luo L; Bu J; Pang D; Wei J; Du C; Xia X; Cui Y; Liu S; Mao Q; Chen M
Int J Mol Sci; 2014 Jan; 15(1):1499-510. PubMed ID: 24451134
[TBL] [Abstract][Full Text] [Related]
2. Rheb1-mTORC1 maintains macrophage differentiation and phagocytosis in mice.
Wang X; Li M; Gao Y; Gao J; Yang W; Liang H; Ji Q; Li Y; Liu H; Huang J; Cheng T; Yuan W
Exp Cell Res; 2016 Jun; 344(2):219-28. PubMed ID: 27163399
[TBL] [Abstract][Full Text] [Related]
3. Rheb1 is required for mTORC1 and myelination in postnatal brain development.
Zou J; Zhou L; Du XX; Ji Y; Xu J; Tian J; Jiang W; Zou Y; Yu S; Gan L; Luo M; Yang Q; Cui Y; Yang W; Xia X; Chen M; Zhao X; Shen Y; Chen PY; Worley PF; Xiao B
Dev Cell; 2011 Jan; 20(1):97-108. PubMed ID: 21238928
[TBL] [Abstract][Full Text] [Related]
4. Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia.
Gao Y; Gao J; Li M; Zheng Y; Wang Y; Zhang H; Wang W; Chu Y; Wang X; Xu M; Cheng T; Ju Z; Yuan W
J Hematol Oncol; 2016 Apr; 9():36. PubMed ID: 27071307
[TBL] [Abstract][Full Text] [Related]
5. Genetic and pharmacological inhibition of Rheb1-mTORC1 signaling exerts cardioprotection against adverse cardiac remodeling in mice.
Wu X; Cao Y; Nie J; Liu H; Lu S; Hu X; Zhu J; Zhao X; Chen J; Chen X; Yang Z; Li X
Am J Pathol; 2013 Jun; 182(6):2005-14. PubMed ID: 23567640
[TBL] [Abstract][Full Text] [Related]
6. Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain.
Zou Y; Jiang W; Wang J; Li Z; Zhang J; Bu J; Zou J; Zhou L; Yu S; Cui Y; Yang W; Luo L; Lu QR; Liu Y; Chen M; Worley PF; Xiao B
J Neurosci; 2014 Nov; 34(47):15764-78. PubMed ID: 25411504
[TBL] [Abstract][Full Text] [Related]
7. Downregulation of Glutamate Transporter EAAT4 by Conditional Knockout of Rheb1 in Cerebellar Purkinje Cells.
Jiang NW; Wang DJ; Xie YJ; Zhou L; Su LD; Li H; Wang QW; Shen Y
Cerebellum; 2016 Jun; 15(3):314-21. PubMed ID: 26194056
[TBL] [Abstract][Full Text] [Related]
8. Cardiac ablation of Rheb1 induces impaired heart growth, endoplasmic reticulum-associated apoptosis and heart failure in infant mice.
Cao Y; Tao L; Shen S; Xiao J; Wu H; Li B; Wu X; Luo W; Xiao Q; Hu X; Liu H; Nie J; Lu S; Yuan B; Han Z; Xiao B; Yang Z; Li X
Int J Mol Sci; 2013 Dec; 14(12):24380-98. PubMed ID: 24351823
[TBL] [Abstract][Full Text] [Related]
9. cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.
Xie J; Ponuwei GA; Moore CE; Willars GB; Tee AR; Herbert TP
Cell Signal; 2011 Dec; 23(12):1927-35. PubMed ID: 21763421
[TBL] [Abstract][Full Text] [Related]
10. Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein.
Sato T; Nakashima A; Guo L; Tamanoi F
J Biol Chem; 2009 May; 284(19):12783-91. PubMed ID: 19299511
[TBL] [Abstract][Full Text] [Related]
11. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
[TBL] [Abstract][Full Text] [Related]
12. Rheb Inhibits Beiging of White Adipose Tissue via PDE4D5-Dependent Downregulation of the cAMP-PKA Signaling Pathway.
Meng W; Liang X; Chen H; Luo H; Bai J; Li G; Zhang Q; Xiao T; He S; Zhang Y; Xu Z; Xiao B; Liu M; Hu F; Liu F
Diabetes; 2017 May; 66(5):1198-1213. PubMed ID: 28242620
[TBL] [Abstract][Full Text] [Related]
13. MCRS1 binds and couples Rheb to amino acid-dependent mTORC1 activation.
Fawal MA; Brandt M; Djouder N
Dev Cell; 2015 Apr; 33(1):67-81. PubMed ID: 25816988
[TBL] [Abstract][Full Text] [Related]
14. Rheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase) protein in a GTP- and effector domain-dependent manner and influences its cellular localization and carbamoyl-phosphate synthetase (CPSase) activity.
Sato T; Akasu H; Shimono W; Matsu C; Fujiwara Y; Shibagaki Y; Heard JJ; Tamanoi F; Hattori S
J Biol Chem; 2015 Jan; 290(2):1096-105. PubMed ID: 25422319
[TBL] [Abstract][Full Text] [Related]
15. Ursolic acid inhibits leucine-stimulated mTORC1 signaling by suppressing mTOR localization to lysosome.
Ou X; Liu M; Luo H; Dong LQ; Liu F
PLoS One; 2014; 9(4):e95393. PubMed ID: 24740400
[TBL] [Abstract][Full Text] [Related]
16. Mammalian target of rapamycin complex I (mTORC1) activity in ras homologue enriched in brain (Rheb)-deficient mouse embryonic fibroblasts.
Groenewoud MJ; Goorden SM; Kassies J; Pellis-van Berkel W; Lamb RF; Elgersma Y; Zwartkruis FJ
PLoS One; 2013; 8(11):e81649. PubMed ID: 24303063
[TBL] [Abstract][Full Text] [Related]
17. Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
Lee MN; Ha SH; Kim J; Koh A; Lee CS; Kim JH; Jeon H; Kim DH; Suh PG; Ryu SH
Mol Cell Biol; 2009 Jul; 29(14):3991-4001. PubMed ID: 19451232
[TBL] [Abstract][Full Text] [Related]
18. Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling.
Wang X; Fonseca BD; Tang H; Liu R; Elia A; Clemens MJ; Bommer UA; Proud CG
J Biol Chem; 2008 Nov; 283(45):30482-92. PubMed ID: 18676370
[TBL] [Abstract][Full Text] [Related]
19. Intact neuronal function in Rheb1 mutant mice: implications for TORC1-based treatments.
Goorden SM; Abs E; Bruinsma CF; Riemslagh FW; van Woerden GM; Elgersma Y
Hum Mol Genet; 2015 Jun; 24(12):3390-8. PubMed ID: 25759467
[TBL] [Abstract][Full Text] [Related]
20. Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic beta-cells leads to increased beta-cell mass and prevention of hyperglycemia.
Hamada S; Hara K; Hamada T; Yasuda H; Moriyama H; Nakayama R; Nagata M; Yokono K
Diabetes; 2009 Jun; 58(6):1321-32. PubMed ID: 19258434
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
