BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 24451646)

  • 1. Small molecules modulation of 14-3-3 protein-protein interactions.
    Mori M; Vignaroli G; Botta M
    Drug Discov Today Technol; 2013 Dec; 10(4):e541-7. PubMed ID: 24451646
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 14-3-3: A Case Study in PPI Modulation.
    Ballone A; Centorrino F; Ottmann C
    Molecules; 2018 Jun; 23(6):. PubMed ID: 29890630
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulators of 14-3-3 Protein-Protein Interactions.
    Stevers LM; Sijbesma E; Botta M; MacKintosh C; Obsil T; Landrieu I; Cau Y; Wilson AJ; Karawajczyk A; Eickhoff J; Davis J; Hann M; O'Mahony G; Doveston RG; Brunsveld L; Ottmann C
    J Med Chem; 2018 May; 61(9):3755-3778. PubMed ID: 28968506
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis of 14-3-3 protein functions.
    Obsil T; Obsilova V
    Semin Cell Dev Biol; 2011 Sep; 22(7):663-72. PubMed ID: 21920446
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Small-molecule stabilization of protein-protein interactions: an underestimated concept in drug discovery?
    Thiel P; Kaiser M; Ottmann C
    Angew Chem Int Ed Engl; 2012 Feb; 51(9):2012-8. PubMed ID: 22308055
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stabilization and inhibition of protein-protein interactions: the 14-3-3 case study.
    Milroy LG; Brunsveld L; Ottmann C
    ACS Chem Biol; 2013 Jan; 8(1):27-35. PubMed ID: 23210482
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction Stabilizers.
    Sijbesma E; Hallenbeck KK; Leysen S; de Vink PJ; Skóra L; Jahnke W; Brunsveld L; Arkin MR; Ottmann C
    J Am Chem Soc; 2019 Feb; 141(8):3524-3531. PubMed ID: 30707565
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Small-molecule modulators of 14-3-3 protein-protein interactions.
    Ottmann C
    Bioorg Med Chem; 2013 Jul; 21(14):4058-62. PubMed ID: 23266179
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stabilizer-Guided Inhibition of Protein-Protein Interactions.
    Milroy LG; Bartel M; Henen MA; Leysen S; Adriaans JM; Brunsveld L; Landrieu I; Ottmann C
    Angew Chem Int Ed Engl; 2015 Dec; 54(52):15720-4. PubMed ID: 26537010
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural biology and drug discovery for protein-protein interactions.
    Jubb H; Higueruelo AP; Winter A; Blundell TL
    Trends Pharmacol Sci; 2012 May; 33(5):241-8. PubMed ID: 22503442
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular insight into specific 14-3-3 modulators: Inhibitors and stabilisers of protein-protein interactions of 14-3-3.
    Hartman AM; Hirsch AKH
    Eur J Med Chem; 2017 Aug; 136():573-584. PubMed ID: 28549334
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.
    Bier D; Bartel M; Sies K; Halbach S; Higuchi Y; Haranosono Y; Brummer T; Kato N; Ottmann C
    ChemMedChem; 2016 Apr; 11(8):911-8. PubMed ID: 26644359
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure, Function, Involvement in Diseases and Targeting of 14-3-3 Proteins: An Update.
    Cau Y; Valensin D; Mori M; Draghi S; Botta M
    Curr Med Chem; 2018; 25(1):5-21. PubMed ID: 28462702
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case.
    Corradi V; Mancini M; Santucci MA; Carlomagno T; Sanfelice D; Mori M; Vignaroli G; Falchi F; Manetti F; Radi M; Botta M
    Bioorg Med Chem Lett; 2011 Nov; 21(22):6867-71. PubMed ID: 21962576
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions.
    Sijbesma E; Visser E; Plitzko K; Thiel P; Milroy LG; Kaiser M; Brunsveld L; Ottmann C
    Nat Commun; 2020 Aug; 11(1):3954. PubMed ID: 32770072
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-based assessment and network analysis of targeting 14-3-3 proteins in prostate cancer.
    Root A; Beizaei A; Ebhardt HA
    Mol Cancer; 2018 Oct; 17(1):156. PubMed ID: 30382885
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small molecules, peptides and natural products: getting a grip on 14-3-3 protein-protein modulation.
    Bartel M; Schäfer A; Stevers LM; Ottmann C
    Future Med Chem; 2014 May; 6(8):903-21. PubMed ID: 24962282
    [TBL] [Abstract][Full Text] [Related]  

  • 18. iPPI-DB: a manually curated and interactive database of small non-peptide inhibitors of protein-protein interactions.
    Labbé CM; Laconde G; Kuenemann MA; Villoutreix BO; Sperandio O
    Drug Discov Today; 2013 Oct; 18(19-20):958-68. PubMed ID: 23688585
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Strategies to search and design stabilizers of protein-protein interactions: a feasibility study.
    Block P; Weskamp N; Wolf A; Klebe G
    Proteins; 2007 Jul; 68(1):170-86. PubMed ID: 17393392
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Experimental and Computational Druggability Exploration of the 14-3-3ζ/SOS1pS
    Ballone A; Picarazzi F; Prosser C; Davis J; Ottmann C; Mori M
    J Chem Inf Model; 2020 Dec; 60(12):6555-6565. PubMed ID: 33138374
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.