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2. Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or antagonized, with cytotoxic agents. Cookson JC; Dai F; Smith V; Heald RA; Laughton CA; Stevens MF; Burger AM Mol Pharmacol; 2005 Dec; 68(6):1551-8. PubMed ID: 16150933 [TBL] [Abstract][Full Text] [Related]
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5. Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes. Gowan SM; Heald R; Stevens MF; Kelland LR Mol Pharmacol; 2001 Nov; 60(5):981-8. PubMed ID: 11641426 [TBL] [Abstract][Full Text] [Related]
6. Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism. Phatak P; Cookson JC; Dai F; Smith V; Gartenhaus RB; Stevens MF; Burger AM Br J Cancer; 2007 Apr; 96(8):1223-33. PubMed ID: 17406367 [TBL] [Abstract][Full Text] [Related]
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