BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

322 related articles for article (PubMed ID: 24456642)

  • 1. Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis.
    Couttas TA; Kain N; Daniels B; Lim XY; Shepherd C; Kril J; Pickford R; Li H; Garner B; Don AS
    Acta Neuropathol Commun; 2014 Jan; 2():9. PubMed ID: 24456642
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer's disease brain.
    Dominguez G; Maddelein ML; Pucelle M; Nicaise Y; Maurage CA; Duyckaerts C; Cuvillier O; Delisle MB
    Acta Neuropathol Commun; 2018 Apr; 6(1):25. PubMed ID: 29615132
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isoform-Dependent Effects of Apolipoprotein E on Sphingolipid Metabolism in Neural Cells.
    Kurano M; Tsukamoto K; Sakai E; Hara M; Yatomi Y
    J Alzheimers Dis; 2022; 85(4):1529-1544. PubMed ID: 34958030
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease.
    Lei M; Teo JD; Song H; McEwen HP; Yup Lee J; Couttas TA; Duncan T; Chesworth R; Bertz J; Przybyla M; Van Eersel J; Heng B; Guillemin GJ; Ittner LM; Fath T; Garner B; Ittner A; Karl T; Don AS
    J Neurosci; 2019 Nov; 39(48):9645-9659. PubMed ID: 31641049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease.
    Ceccom J; Loukh N; Lauwers-Cances V; Touriol C; Nicaise Y; Gentil C; Uro-Coste E; Pitson S; Maurage CA; Duyckaerts C; Cuvillier O; Delisle MB
    Acta Neuropathol Commun; 2014 Jan; 2():12. PubMed ID: 24468113
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells.
    Pyszko J; Strosznajder JB
    Mol Neurobiol; 2014 Aug; 50(1):38-48. PubMed ID: 24399507
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dysregulation of sphingosine-1-phosphate (S1P) and S1P receptor 1 signaling in the 5xFAD mouse model of Alzheimer's disease.
    Jung Y; Lopez-Benitez J; Tognoni CM; Carreras I; Dedeoglu A
    Brain Res; 2023 Jan; 1799():148171. PubMed ID: 36410428
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of sphingosine kinase 1/S1P signaling impairs cell growth and survival of neurons and progenitor cells in the developing sensory ganglia.
    Meng H; Yuan Y; Lee VM
    PLoS One; 2011; 6(11):e27150. PubMed ID: 22096531
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear SphK2/S1P signaling is a key regulator of ApoE production and Aβ uptake in astrocytes.
    Komai M; Noda Y; Ikeda A; Kaneshiro N; Kamikubo Y; Sakurai T; Uehara T; Takasugi N
    J Lipid Res; 2024 Mar; 65(3):100510. PubMed ID: 38280459
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Beneficial Effects of Fingolimod in Alzheimer's Disease: Molecular Mechanisms and Therapeutic Potential.
    Angelopoulou E; Piperi C
    Neuromolecular Med; 2019 Sep; 21(3):227-238. PubMed ID: 31313064
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sphingosine kinase 1/sphingosine-1-phosphate regulates the expression of interleukin-17A in activated microglia in cerebral ischemia/reperfusion.
    Lv M; Zhang D; Dai D; Zhang W; Zhang L
    Inflamm Res; 2016 Jul; 65(7):551-62. PubMed ID: 27002656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting sphingosine-1-phosphate in hematologic malignancies.
    Stevenson CE; Takabe K; Nagahashi M; Milstien S; Spiegel S
    Anticancer Agents Med Chem; 2011 Nov; 11(9):794-8. PubMed ID: 21707492
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modulation of Neurolipid Signaling and Specific Lipid Species in the Triple Transgenic Mouse Model of Alzheimer's Disease.
    González de San Román E; Llorente-Ovejero A; Martínez-Gardeazabal J; Moreno-Rodríguez M; Giménez-Llort L; Manuel I; Rodríguez-Puertas R
    Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830150
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genotype-related differences of hippocampal apolipoprotein E levels only in early stages of neuropathological changes in Alzheimer's disease.
    Glöckner F; Meske V; Ohm TG
    Neuroscience; 2002; 114(4):1103-14. PubMed ID: 12379263
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Building a better sphingosine kinase-1 inhibitor.
    Lynch KR
    Biochem J; 2012 May; 444(1):e1-2. PubMed ID: 22533672
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1.
    Zhao Y; Kalari SK; Usatyuk PV; Gorshkova I; He D; Watkins T; Brindley DN; Sun C; Bittman R; Garcia JG; Berdyshev EV; Natarajan V
    J Biol Chem; 2007 May; 282(19):14165-77. PubMed ID: 17379599
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of sphingosine-1-phosphate lyase rescues sphingosine kinase-1-knockout phenotype following murine cardiac arrest.
    Gorshkova IA; Wang H; Orbelyan GA; Goya J; Natarajan V; Beiser DG; Vanden Hoek TL; Berdyshev EV
    Life Sci; 2013 Sep; 93(9-11):359-66. PubMed ID: 23892195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bone marrow mesenchymal stem cells-derived exosomes reduce Aβ deposition and improve cognitive function recovery in mice with Alzheimer's disease by activating sphingosine kinase/sphingosine-1-phosphate signaling pathway.
    Wang X; Yang G
    Cell Biol Int; 2021 Apr; 45(4):775-784. PubMed ID: 33300254
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sphingosine kinase 2 and sphingosine-1-phosphate promotes mitochondrial function in dopaminergic neurons of mouse model of Parkinson's disease and in MPP+ -treated MN9D cells in vitro.
    Sivasubramanian M; Kanagaraj N; Dheen ST; Tay SS
    Neuroscience; 2015 Apr; 290():636-48. PubMed ID: 25637806
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen.
    Schröder M; Richter C; Juan MH; Maltusch K; Giegold O; Quintini G; Pfeilschifter JM; Huwiler A; Radeke HH
    Mol Immunol; 2011 May; 48(9-10):1139-48. PubMed ID: 21435724
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.