BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

84 related articles for article (PubMed ID: 2445673)

  • 21. Synthesis and characterization of O6-(2-chloroethyl)guanine: a putative intermediate in the cytotoxic reaction of chloroethylnitrosoureas with DNA.
    Parker S; Kirk MC; Ludlum DB
    Biochem Biophys Res Commun; 1987 Nov; 148(3):1124-8. PubMed ID: 3689390
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Complementary addressed modification of nucleic acids with the alkylating derivatives of oligothymidylate ethyl phosphotriesters. Effect of the phosphotriester fragments' configuration.
    Abramova TV; Vlassov VV; Lebedev AV; Ryte AS
    FEBS Lett; 1988 Aug; 236(1):243-5. PubMed ID: 2456955
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The alkaline hydrolysis of phosphotriesters in alkylated mammalian DNA.
    Crathorn AR; Shooter KV
    Biochim Biophys Acta; 1982 May; 697(2):259-61. PubMed ID: 7104358
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Analysis of alkylated sites at N-3 and N-7 positions of purines as an indicator for chemical carcinogens.
    Mhaskar DN; Chang MJ; Hart RW; D'Ambrosio SM
    Cancer Res; 1981 Jan; 41(1):223-9. PubMed ID: 7448762
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.
    Jansen JG; Vrieling H; van Teijlingen CM; Mohn GR; Tates AD; van Zeeland AA
    Cancer Res; 1995 May; 55(9):1875-82. PubMed ID: 7728755
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Effect of cations on the formation of DNA alkylation products in DNA reacted with 1-(2-Chloroethyl)-1-nitrosourea.
    Bodell WJ
    Chem Res Toxicol; 1999 Oct; 12(10):965-70. PubMed ID: 10525273
    [TBL] [Abstract][Full Text] [Related]  

  • 27. DNA sequence selectivity of guanine-N7 alkylation by three antitumor chloroethylating agents.
    Hartley JA; Gibson NW; Kohn KW; Mattes WB
    Cancer Res; 1986 Apr; 46(4 Pt 2):1943-7. PubMed ID: 3004713
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Modelling the probability distribution of the number of DNA double-strand breaks due to sporadic alkylation of nucleotide bases.
    Walters K
    J Theor Biol; 2007 Mar; 245(1):161-8. PubMed ID: 17087972
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Chemical synthesis and detection of the cross-link 1-[N3-(2'-deoxycytidyl)]-2-[N1-(2'-deoxyguanosinyl)]ethane in DNA reacted with 1-(2-chloroethyl)-1-nitrosourea.
    Bodell WJ; Pongracz K
    Chem Res Toxicol; 1993; 6(4):434-8. PubMed ID: 8374039
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C.
    Suresh Kumar G; Lipman R; Cummings J; Tomasz M
    Biochemistry; 1997 Nov; 36(46):14128-36. PubMed ID: 9369485
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Kinetic analysis of sequence-specific alkylation of DNA by pyrimidine oligodeoxyribonucleotide-directed triple-helix formation.
    Taylor MJ; Dervan PB
    Bioconjug Chem; 1997; 8(3):354-64. PubMed ID: 9177841
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Alkylation of DNA in rats by N-nitrosomethyl-(2-hydroxyethyl)amine: dose response and persistence of the alkylated lesions in vivo.
    Koepke SR; Kroeger-Koepke MB; Bosan W; Thomas BJ; Alvord WG; Michejda CJ
    Cancer Res; 1988 Mar; 48(6):1537-42. PubMed ID: 3345527
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Depurinating acylfulvene-DNA adducts: characterizing cellular chemical reactions of a selective antitumor agent.
    Gong J; Vaidyanathan VG; Yu X; Kensler TW; Peterson LA; Sturla SJ
    J Am Chem Soc; 2007 Feb; 129(7):2101-11. PubMed ID: 17256933
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Detection of DNA alkylphosphotriesters by 32P postlabeling: evidence for the nonrandom manifestation of phosphotriester lesions in vivo.
    Guichard Y; Jones GD; Farmer PB
    Cancer Res; 2000 Mar; 60(5):1276-82. PubMed ID: 10728687
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Binding of metabolites of cyclophosphamide to DNA in a rat liver microsomal system and in vivo in mice.
    Hemminki K
    Cancer Res; 1985 Sep; 45(9):4237-43. PubMed ID: 4028012
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Reaction of DNA with alkylating agents. Quantitation of alkylation by ethylnitrosourea of oxygen and nitrogen sites on poly[dA-dT] including phosphotriester formation.
    Jensen DE; Reed DJ
    Biochemistry; 1978 Nov; 17(24):5098-107. PubMed ID: 728391
    [No Abstract]   [Full Text] [Related]  

  • 37. Formation of cyclic adducts in nucleic acids by the haloethylnitrosoureas.
    Ludlum DB
    IARC Sci Publ; 1986; (70):137-46. PubMed ID: 3793169
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Non-identical electronic characters of the internucleotidic phosphates in RNA modulate the chemical reactivity of the phosphodiester bonds.
    Barman J; Acharya S; Zhou C; Chatterjee S; Engström A; Chattopadhyaya J
    Org Biomol Chem; 2006 Mar; 4(5):928-41. PubMed ID: 16493477
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Nucleic acid alkylation by free radical metabolites of ethanol. Formation of 8-(1-hydroxyethyl)guanine and 8-(2-hydroxyethyl)guanine adducts.
    Nakao LS; Augusto O
    Chem Res Toxicol; 1998 Aug; 11(8):888-94. PubMed ID: 9705750
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Double sugar and phosphate backbone-constrained nucleotides: synthesis, structure, stability, and their incorporation into oligodeoxynucleotides.
    Zhou C; Plashkevych O; Chattopadhyaya J
    J Org Chem; 2009 May; 74(9):3248-65. PubMed ID: 19348480
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.