278 related articles for article (PubMed ID: 24471412)
1. Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors.
Plano D; Amin S; Sharma AK
J Med Chem; 2014 Jul; 57(13):5509-24. PubMed ID: 24471412
[TBL] [Abstract][Full Text] [Related]
2. Sphingosine kinase inhibitors: A patent review.
Cao M; Ji C; Zhou Y; Huang W; Ni W; Tong X; Wei JF
Int J Mol Med; 2018 May; 41(5):2450-2460. PubMed ID: 29484372
[TBL] [Abstract][Full Text] [Related]
3. Drugging sphingosine kinases.
Santos WL; Lynch KR
ACS Chem Biol; 2015 Jan; 10(1):225-33. PubMed ID: 25384187
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of sphingoid analogs as inhibitors of sphingosine kinases.
Kim JW; Kim YW; Inagaki Y; Hwang YA; Mitsutake S; Ryu YW; Lee WK; Ha HJ; Park CS; Igarashi Y
Bioorg Med Chem; 2005 May; 13(10):3475-85. PubMed ID: 15848761
[TBL] [Abstract][Full Text] [Related]
5. "Dicing and Splicing" Sphingosine Kinase and Relevance to Cancer.
Haddadi N; Lin Y; Simpson AM; Nassif NT; McGowan EM
Int J Mol Sci; 2017 Sep; 18(9):. PubMed ID: 28869494
[TBL] [Abstract][Full Text] [Related]
6. Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments.
Magli E; Corvino A; Fiorino F; Frecentese F; Perissutti E; Saccone I; Santagada V; Caliendo G; Severino B
Curr Pharm Des; 2019; 25(9):956-968. PubMed ID: 30947653
[TBL] [Abstract][Full Text] [Related]
7. Structure guided design of a series of sphingosine kinase (SphK) inhibitors.
Gustin DJ; Li Y; Brown ML; Min X; Schmitt MJ; Wanska M; Wang X; Connors R; Johnstone S; Cardozo M; Cheng AC; Jeffries S; Franks B; Li S; Shen S; Wong M; Wesche H; Xu G; Carlson TJ; Plant M; Morgenstern K; Rex K; Schmitt J; Coxon A; Walker N; Kayser F; Wang Z
Bioorg Med Chem Lett; 2013 Aug; 23(16):4608-16. PubMed ID: 23845219
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors.
Raje MR; Knott K; Kharel Y; Bissel P; Lynch KR; Santos WL
Bioorg Med Chem; 2012 Jan; 20(1):183-94. PubMed ID: 22137932
[TBL] [Abstract][Full Text] [Related]
9. The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen.
Schröder M; Richter C; Juan MH; Maltusch K; Giegold O; Quintini G; Pfeilschifter JM; Huwiler A; Radeke HH
Mol Immunol; 2011 May; 48(9-10):1139-48. PubMed ID: 21435724
[TBL] [Abstract][Full Text] [Related]
10. Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.
Schnute ME; McReynolds MD; Kasten T; Yates M; Jerome G; Rains JW; Hall T; Chrencik J; Kraus M; Cronin CN; Saabye M; Highkin MK; Broadus R; Ogawa S; Cukyne K; Zawadzke LE; Peterkin V; Iyanar K; Scholten JA; Wendling J; Fujiwara H; Nemirovskiy O; Wittwer AJ; Nagiec MM
Biochem J; 2012 May; 444(1):79-88. PubMed ID: 22397330
[TBL] [Abstract][Full Text] [Related]
11. Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis.
Lai WQ; Irwan AW; Goh HH; Howe HS; Yu DT; Valle-Oñate R; McInnes IB; Melendez AJ; Leung BP
J Immunol; 2008 Dec; 181(11):8010-7. PubMed ID: 19017993
[TBL] [Abstract][Full Text] [Related]
12. Sphingosine kinase, sphingosine-1-phosphate, and apoptosis.
Maceyka M; Payne SG; Milstien S; Spiegel S
Biochim Biophys Acta; 2002 Dec; 1585(2-3):193-201. PubMed ID: 12531554
[TBL] [Abstract][Full Text] [Related]
13. Sphingosine kinase and sphingosine-1-phosphate receptor signaling pathway in inflammatory gastrointestinal disease and cancers: A novel therapeutic target.
Sukocheva OA; Furuya H; Ng ML; Friedemann M; Menschikowski M; Tarasov VV; Chubarev VN; Klochkov SG; Neganova ME; Mangoni AA; Aliev G; Bishayee A
Pharmacol Ther; 2020 Mar; 207():107464. PubMed ID: 31863815
[TBL] [Abstract][Full Text] [Related]
14. Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels.
Kharel Y; Morris EA; Congdon MD; Thorpe SB; Tomsig JL; Santos WL; Lynch KR
J Pharmacol Exp Ther; 2015 Oct; 355(1):23-31. PubMed ID: 26243740
[TBL] [Abstract][Full Text] [Related]
15. The sphingosine kinase-1/sphingosine-1-phosphate axis in cancer: Potential target for anticancer therapy.
Zheng X; Li W; Ren L; Liu J; Pang X; Chen X; Kang D; Wang J; Du G
Pharmacol Ther; 2019 Mar; 195():85-99. PubMed ID: 30347210
[TBL] [Abstract][Full Text] [Related]
16. Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes.
Tao R; Zhang J; Vessey DA; Honbo N; Karliner JS
Cardiovasc Res; 2007 Apr; 74(1):56-63. PubMed ID: 17320845
[TBL] [Abstract][Full Text] [Related]
17. Sphingosine kinase and sphingosine-1-phosphate regulate migration, endocytosis and apoptosis of dendritic cells.
Eigenbrod S; Derwand R; Jakl V; Endres S; Eigler A
Immunol Invest; 2006; 35(2):149-65. PubMed ID: 16698674
[TBL] [Abstract][Full Text] [Related]
18. Sphingosine kinase inhibitors: a review of patent literature (2006-2015).
Lynch KR; Thorpe SB; Santos WL
Expert Opin Ther Pat; 2016 Dec; 26(12):1409-1416. PubMed ID: 27539678
[TBL] [Abstract][Full Text] [Related]
19. Effect of alkyl chain length on sphingosine kinase 2 selectivity.
Knott K; Kharel Y; Raje MR; Lynch KR; Santos WL
Bioorg Med Chem Lett; 2012 Nov; 22(22):6817-20. PubMed ID: 22321213
[TBL] [Abstract][Full Text] [Related]
20. Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma.
Nicholas SE; Rowsey TG; Priyadarsini S; Mandal NA; Karamichos D
PLoS One; 2017; 12(8):e0182390. PubMed ID: 28806736
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
