These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 24486377)

  • 1. Mode of action of the positive modulator PNU-120596 on α7 nicotinic acetylcholine receptors.
    Szabo AK; Pesti K; Mike A; Vizi ES
    Neuropharmacology; 2014 Jun; 81():42-54. PubMed ID: 24486377
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic properties and open probability of α7 nicotinic acetylcholine receptors.
    Pesti K; Szabo AK; Mike A; Vizi ES
    Neuropharmacology; 2014 Jun; 81():101-15. PubMed ID: 24486379
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors.
    Marotta CB; Lester HA; Dougherty DA
    Chem Biol; 2015 Aug; 22(8):1063-73. PubMed ID: 26211363
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Competitive binding at a nicotinic receptor transmembrane site of two α7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization.
    Collins T; Young GT; Millar NS
    Neuropharmacology; 2011 Dec; 61(8):1306-13. PubMed ID: 21820451
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization.
    Hurst RS; Hajós M; Raggenbass M; Wall TM; Higdon NR; Lawson JA; Rutherford-Root KL; Berkenpas MB; Hoffmann WE; Piotrowski DW; Groppi VE; Allaman G; Ogier R; Bertrand S; Bertrand D; Arneric SP
    J Neurosci; 2005 Apr; 25(17):4396-405. PubMed ID: 15858066
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Physiological concentrations of choline activate native alpha7-containing nicotinic acetylcholine receptors in the presence of PNU-120596 [1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)-urea].
    Gusev AG; Uteshev VV
    J Pharmacol Exp Ther; 2010 Feb; 332(2):588-98. PubMed ID: 19923442
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of functional α7-containing nAChRs in hippocampal CA1 pyramidal neurons by physiological levels of choline in the presence of PNU-120596.
    Kalappa BI; Gusev AG; Uteshev VV
    PLoS One; 2010 Nov; 5(11):e13964. PubMed ID: 21103043
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human α7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis.
    Scheffel C; Niessen KV; Rappenglück S; Wanner KT; Thiermann H; Worek F; Seeger T
    Toxicol Lett; 2018 Sep; 293():157-166. PubMed ID: 29191791
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PNU-120596, a positive allosteric modulator of mammalian α7 nicotinic acetylcholine receptor, is a negative modulator of ligand-gated chloride-selective channels of the gastropod Lymnaea stagnalis.
    Vulfius CA; Lebedev DS; Kryukova EV; Kudryavtsev DS; Kolbaev SN; Utkin YN; Tsetlin VI
    J Neurochem; 2020 Nov; 155(3):274-284. PubMed ID: 32248535
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The dual effect of PNU-120596 on α7 nicotinic acetylcholine receptor channels.
    Kalappa BI; Uteshev VV
    Eur J Pharmacol; 2013 Oct; 718(1-3):226-34. PubMed ID: 24036349
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Counteracting desensitization of human α7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning.
    Scheffel C; Niessen KV; Rappenglück S; Wanner KT; Thiermann H; Worek F; Seeger T
    Toxicol Lett; 2018 Sep; 293():149-156. PubMed ID: 29248576
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A positive allosteric modulator of α7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia.
    Kalappa BI; Sun F; Johnson SR; Jin K; Uteshev VV
    Br J Pharmacol; 2013 Aug; 169(8):1862-78. PubMed ID: 23713819
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vivo pharmacological interactions between a type II positive allosteric modulator of α7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model.
    Freitas K; Negus SS; Carroll FI; Damaj MI
    Br J Pharmacol; 2013 Jun; 169(3):567-79. PubMed ID: 23004024
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An allosteric modulator of alpha7 nicotinic receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), causes conformational changes in the extracellular ligand binding domain similar to those caused by acetylcholine.
    Barron SC; McLaughlin JT; See JA; Richards VL; Rosenberg RL
    Mol Pharmacol; 2009 Aug; 76(2):253-63. PubMed ID: 19411608
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stable desensitization of α
    Pismataro MC; Horenstein NA; Stokes C; Dallanoce C; Thakur GA; Papke RL
    Eur J Pharmacol; 2021 Aug; 905():174179. PubMed ID: 34004208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigation of the molecular mechanism of the α7 nicotinic acetylcholine receptor positive allosteric modulator PNU-120596 provides evidence for two distinct desensitized states.
    Williams DK; Wang J; Papke RL
    Mol Pharmacol; 2011 Dec; 80(6):1013-32. PubMed ID: 21885620
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Allosteric Agonism of
    Gulsevin A; Papke RL; Stokes C; Garai S; Thakur GA; Quadri M; Horenstein NA
    Mol Pharmacol; 2019 Jun; 95(6):606-614. PubMed ID: 30944209
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional properties of alpha7 nicotinic acetylcholine receptors co-expressed with RIC-3 in a stable recombinant CHO-K1 cell line.
    Roncarati R; Seredenina T; Jow B; Jow F; Papini S; Kramer A; Bothmann H; Dunlop J; Terstappen GC
    Assay Drug Dev Technol; 2008 Apr; 6(2):181-93. PubMed ID: 18471073
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel interplay between agonist and calcium binding sites modulates drug potentiation of α7 acetylcholine receptor.
    Mukhtasimova N; Bouzat C; Sine SM
    Cell Mol Life Sci; 2024 Aug; 81(1):332. PubMed ID: 39110172
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of compounds on nicotinic acetylcholine receptor alpha7 channels using higher throughput electrophysiology.
    Friis S; Mathes C; Sunesen M; Bowlby MR; Dunlop J
    J Neurosci Methods; 2009 Feb; 177(1):142-8. PubMed ID: 19000713
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.