177 related articles for article (PubMed ID: 24486383)
1. Aqueous extract of Gardenia jasminoides targeting oxidative stress to reduce polyQ aggregation in cell models of spinocerebellar ataxia 3.
Chang KH; Chen WL; Wu YR; Lin TH; Wu YC; Chao CY; Lin JY; Lee LC; Chen YC; Lee-Chen GJ; Chen CM
Neuropharmacology; 2014 Jun; 81():166-75. PubMed ID: 24486383
[TBL] [Abstract][Full Text] [Related]
2. The potential of indole and a synthetic derivative for polyQ aggregation reduction by enhancement of the chaperone and autophagy systems.
Lin CH; Wu YR; Kung PJ; Chen WL; Lee LC; Lin TH; Chao CY; Chen CM; Chang KH; Janreddy D; Lee-Chen GJ; Yao CF
ACS Chem Neurosci; 2014 Oct; 5(10):1063-74. PubMed ID: 25197952
[TBL] [Abstract][Full Text] [Related]
3. Aqueous extract of Glycyrrhiza inflata inhibits aggregation by upregulating PPARGC1A and NFE2L2-ARE pathways in cell models of spinocerebellar ataxia 3.
Chen CM; Weng YT; Chen WL; Lin TH; Chao CY; Lin CH; Chen IC; Lee LC; Lin HY; Wu YR; Chen YC; Chang KH; Tang HY; Cheng ML; Lee-Chen GJ; Lin JY
Free Radic Biol Med; 2014 Jun; 71():339-350. PubMed ID: 24675225
[TBL] [Abstract][Full Text] [Related]
4. Novel Lactulose and Melibiose Targeting Autophagy to Reduce PolyQ Aggregation in Cell Models of Spinocerebellar Ataxia 3.
Lin CH; Wu YR; Yang JM; Chen WL; Chao CY; Chen IC; Lin TH; Wu YC; Hsu KC; Chen CM; Lee GC; Hsieh-Li HM; Lee CM; Lee-Chen GJ
CNS Neurol Disord Drug Targets; 2016; 15(3):351-9. PubMed ID: 26295831
[TBL] [Abstract][Full Text] [Related]
5. Targeting Ubiquitin Proteasome Pathway with Traditional Chinese Medicine for Treatment of Spinocerebellar Ataxia Type 3.
Chen IC; Chang CN; Chen WL; Lin TH; Chao CY; Lin CH; Lin HY; Cheng ML; Chiang MC; Lin JY; Wu YR; Lee-Chen GJ; Chen CM
Am J Chin Med; 2019; 47(1):63-95. PubMed ID: 30612452
[TBL] [Abstract][Full Text] [Related]
6. Aqueous Extract of Paeonia lactiflora and Paeoniflorin as Aggregation Reducers Targeting Chaperones in Cell Models of Spinocerebellar Ataxia 3.
Chang KH; Chen WL; Lee LC; Lin CH; Kung PJ; Lin TH; Wu YC; Wu YR; Chen YC; Lee-Chen GJ; Chen CM
Evid Based Complement Alternat Med; 2013; 2013():471659. PubMed ID: 23533486
[TBL] [Abstract][Full Text] [Related]
7. Ataxin-3 protein modification as a treatment strategy for spinocerebellar ataxia type 3: removal of the CAG containing exon.
Evers MM; Tran HD; Zalachoras I; Pepers BA; Meijer OC; den Dunnen JT; van Ommen GJ; Aartsma-Rus A; van Roon-Mom WM
Neurobiol Dis; 2013 Oct; 58():49-56. PubMed ID: 23659897
[TBL] [Abstract][Full Text] [Related]
8. FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.
Araujo J; Breuer P; Dieringer S; Krauss S; Dorn S; Zimmermann K; Pfeifer A; Klockgether T; Wuellner U; Evert BO
Hum Mol Genet; 2011 Aug; 20(15):2928-41. PubMed ID: 21536589
[TBL] [Abstract][Full Text] [Related]
9. A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3.
Chen ZS; Huang X; Talbot K; Chan HYE
Cell Death Dis; 2021 Feb; 12(2):136. PubMed ID: 33542212
[TBL] [Abstract][Full Text] [Related]
10. Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3.
Haacke A; Broadley SA; Boteva R; Tzvetkov N; Hartl FU; Breuer P
Hum Mol Genet; 2006 Feb; 15(4):555-68. PubMed ID: 16407371
[TBL] [Abstract][Full Text] [Related]
11. Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model.
Ajayi A; Yu X; Lindberg S; Langel U; Ström AL
BMC Neurosci; 2012 Jul; 13():86. PubMed ID: 22827889
[TBL] [Abstract][Full Text] [Related]
12. CDK5 protects from caspase-induced Ataxin-3 cleavage and neurodegeneration.
Liman J; Deeg S; Voigt A; Voßfeldt H; Dohm CP; Karch A; Weishaupt J; Schulz JB; Bähr M; Kermer P
J Neurochem; 2014 Jun; 129(6):1013-23. PubMed ID: 24548080
[TBL] [Abstract][Full Text] [Related]
13. Investigating the therapeutic effects of novel compounds targeting inflammatory IL-1β and IL-6 signaling pathways in spinocerebellar ataxia type 3.
Chen IC; Chen WL; Chang KH; Lee JW; Lin TH; Lin W; Chen CM; Lee-Chen GJ
Eur J Pharmacol; 2024 Mar; 967():176370. PubMed ID: 38320719
[TBL] [Abstract][Full Text] [Related]
14. Crocin and geniposide profiles and radical scavenging activity of gardenia fruits (Gardenia jasminoides Ellis) from different cultivars and at the various stages of maturation.
Chen Y; Zhang H; Li YX; Cai L; Huang J; Zhao C; Jia L; Buchanan R; Yang T; Jiang LJ
Fitoterapia; 2010 Jun; 81(4):269-73. PubMed ID: 19815056
[TBL] [Abstract][Full Text] [Related]
15. [Polyglutamine-expanded ataxin-3 is degraded by autophagy].
Xiao H; Tang J; Hu Z; Tan J; Tang B; Jiang Z
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2010 Feb; 27(1):23-8. PubMed ID: 20140862
[TBL] [Abstract][Full Text] [Related]
16. Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation.
Chiu YJ; Lin SA; Chen WL; Lin TH; Lin CH; Yao CF; Lin W; Wu YR; Chang KH; Lee-Chen GJ; Chen CM
Aging (Albany NY); 2020 Nov; 12(23):23619-23646. PubMed ID: 33196459
[TBL] [Abstract][Full Text] [Related]
17. Polyglutamine diseases: the special case of ataxin-3 and Machado-Joseph disease.
Matos CA; de Macedo-Ribeiro S; Carvalho AL
Prog Neurobiol; 2011 Sep; 95(1):26-48. PubMed ID: 21740957
[TBL] [Abstract][Full Text] [Related]
18. A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD.
Switonski PM; Szlachcic WJ; Krzyzosiak WJ; Figiel M
Neurobiol Dis; 2015 Jan; 73():174-88. PubMed ID: 25301414
[TBL] [Abstract][Full Text] [Related]
19. Transcriptional repression and cell death induced by nuclear aggregates of non-polyglutamine protein.
Fu L; Gao YS; Sztul E
Neurobiol Dis; 2005 Dec; 20(3):656-65. PubMed ID: 15964198
[TBL] [Abstract][Full Text] [Related]
20. Antithrombotic activities of aqueous extract from Gardenia jasminoides and its main constituent.
Zhang HY; Liu H; Yang M; Wei SF
Pharm Biol; 2013 Feb; 51(2):221-5. PubMed ID: 23116215
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
