234 related articles for article (PubMed ID: 24486569)
1. PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors.
Martínez-Díez M; Guillén-Navarro MJ; Pera B; Bouchet BP; Martínez-Leal JF; Barasoain I; Cuevas C; Andreu JM; García-Fernández LF; Díaz JF; Avilés P; Galmarini CM
Biochem Pharmacol; 2014 Apr; 88(3):291-302. PubMed ID: 24486569
[TBL] [Abstract][Full Text] [Related]
2. New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.
Pera B; Barasoain I; Pantazopoulou A; Canales A; Matesanz R; Rodriguez-Salarichs J; García-Fernandez LF; Moneo V; Jiménez-Barbero J; Galmarini CM; Cuevas C; Peñalva MA; Díaz JF; Andreu JM
ACS Chem Biol; 2013 Sep; 8(9):2084-94. PubMed ID: 23859655
[TBL] [Abstract][Full Text] [Related]
3. Isolation and first total synthesis of PM050489 and PM060184, two new marine anticancer compounds.
Martín MJ; Coello L; Fernández R; Reyes F; Rodríguez A; Murcia C; Garranzo M; Mateo C; Sánchez-Sancho F; Bueno S; de Eguilior C; Francesch A; Munt S; Cuevas C
J Am Chem Soc; 2013 Jul; 135(27):10164-71. PubMed ID: 23750450
[TBL] [Abstract][Full Text] [Related]
4. Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells.
Galmarini CM; Martin M; Bouchet BP; Guillen-Navarro MJ; Martínez-Diez M; Martinez-Leal JF; Akhmanova A; Aviles P
BMC Cancer; 2018 Feb; 18(1):164. PubMed ID: 29415678
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study.
Wang L; Li X; Cui H; Lei X; Liu H; Wang Q; Li Y
Bioorg Med Chem Lett; 2021 Nov; 51():128355. PubMed ID: 34508844
[TBL] [Abstract][Full Text] [Related]
6. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
Kuo CC; Hsieh HP; Pan WY; Chen CP; Liou JP; Lee SJ; Chang YL; Chen LT; Chen CT; Chang JY
Cancer Res; 2004 Jul; 64(13):4621-8. PubMed ID: 15231674
[TBL] [Abstract][Full Text] [Related]
7. Tricyclic pyrone analogs: a new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo.
Perchellet EM; Ladesich JB; Magill MJ; Chen Y; Hua DH; Perchellet JP
Anticancer Drugs; 1999 Jun; 10(5):489-504. PubMed ID: 10477169
[TBL] [Abstract][Full Text] [Related]
8. Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
Guzmán EA; Xu Q; Pitts TP; Mitsuhashi KO; Baker C; Linley PA; Oestreicher J; Tendyke K; Winder PL; Suh EM; Wright AE
Int J Cancer; 2016 Nov; 139(9):2116-26. PubMed ID: 27376928
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
Wang F; Yang Z; Liu Y; Ma L; Wu Y; He L; Shao M; Yu K; Wu W; Pu Y; Nie C; Chen L
Bioorg Med Chem; 2015 Jul; 23(13):3337-50. PubMed ID: 25937236
[TBL] [Abstract][Full Text] [Related]
10. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
Yan J; Pang Y; Sheng J; Wang Y; Chen J; Hu J; Huang L; Li X
Biochem Pharmacol; 2015 Sep; 97(1):51-61. PubMed ID: 26212540
[TBL] [Abstract][Full Text] [Related]
11. Molecular mechanisms of the antitumor activity of SB225002: a novel microtubule inhibitor.
Goda AE; Koyama M; Sowa Y; Elokely KM; Yoshida T; Kim BY; Sakai T
Biochem Pharmacol; 2013 Jun; 85(12):1741-52. PubMed ID: 23611835
[TBL] [Abstract][Full Text] [Related]
12. Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells.
Chang JY; Chang CY; Kuo CC; Chen LT; Wein YS; Kuo YH
Mol Pharmacol; 2004 Jan; 65(1):77-84. PubMed ID: 14722239
[TBL] [Abstract][Full Text] [Related]
13. Effect of the Marine Polyketide Plocabulin on Tumor Progression.
Turrini E; Maffei F; Fimognari C
Mar Drugs; 2022 Dec; 21(1):. PubMed ID: 36662211
[TBL] [Abstract][Full Text] [Related]
14. Induction of apoptosis through tubulin inhibition in human cancer cells by new chromene-based chalcones.
Aryapour H; Riazi GH; Ahmadian S; Foroumadi A; Mahdavi M; Emami S
Pharm Biol; 2012 Dec; 50(12):1551-60. PubMed ID: 22984888
[TBL] [Abstract][Full Text] [Related]
15. N-(2,6-dimethoxypyridine-3-yl)-9-methylcarbazole-3-sulfonamide as a novel tubulin ligand against human cancer.
Wang YM; Hu LX; Liu ZM; You XF; Zhang SH; Qu JR; Li ZR; Li Y; Kong WJ; He HW; Shao RG; Zhang LR; Peng ZG; Boykin DW; Jiang JD
Clin Cancer Res; 2008 Oct; 14(19):6218-27. PubMed ID: 18829501
[TBL] [Abstract][Full Text] [Related]
16. Discovery of potent cytotoxic ortho-aryl chalcones as new scaffold targeting tubulin and mitosis with affinity-based fluorescence.
Zhu C; Zuo Y; Wang R; Liang B; Yue X; Wen G; Shang N; Huang L; Chen Y; Du J; Bu X
J Med Chem; 2014 Aug; 57(15):6364-82. PubMed ID: 25061803
[TBL] [Abstract][Full Text] [Related]
17. Molecular basis of resistance to the microtubule-depolymerizing antitumor compound plocabulin.
Pantazopoulou A; Galmarini CM; Peñalva MA
Sci Rep; 2018 Jun; 8(1):8616. PubMed ID: 29872155
[TBL] [Abstract][Full Text] [Related]
18. Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.
Wong VK; Chiu P; Chung SS; Chow LM; Zhao YZ; Yang BB; Ko BC
Clin Cancer Res; 2005 Aug; 11(16):6002-11. PubMed ID: 16115945
[TBL] [Abstract][Full Text] [Related]
19. DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.
Qiao F; Zuo D; Shen X; Qi H; Wang H; Zhang W; Wu Y
Cancer Chemother Pharmacol; 2012 Aug; 70(2):259-70. PubMed ID: 22752214
[TBL] [Abstract][Full Text] [Related]
20. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]