These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 24492962)

  • 21. Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases.
    Voss M; Schröder B; Fluhrer R
    Biochim Biophys Acta; 2013 Dec; 1828(12):2828-39. PubMed ID: 24099004
    [TBL] [Abstract][Full Text] [Related]  

  • 22. On the track of intramembrane clippers: the SPPL2a/b proteases caught in the act in animal models.
    Trávníčková K; Stříšovský K
    FEBS J; 2023 May; 290(9):2306-2310. PubMed ID: 36310421
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Physiological functions of SPP/SPPL intramembrane proteases.
    Mentrup T; Cabrera-Cabrera F; Fluhrer R; Schröder B
    Cell Mol Life Sci; 2020 Aug; 77(15):2959-2979. PubMed ID: 32052089
    [TBL] [Abstract][Full Text] [Related]  

  • 24. In vitro cleavage of tumor necrosis factor α (TNFα) by Signal-Peptide-Peptidase-like 2b (SPPL2b) resembles mechanistic principles observed in the cellular context.
    Sharrouf K; Schlosser C; Mildenberger S; Fluhrer R; Hoeppner S
    Chem Biol Interact; 2024 May; 395():111006. PubMed ID: 38636792
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Intramembrane proteolysis within lysosomes.
    Schröder B; Saftig P
    Ageing Res Rev; 2016 Dec; 32():51-64. PubMed ID: 27143694
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3.
    Krawitz P; Haffner C; Fluhrer R; Steiner H; Schmid B; Haass C
    J Biol Chem; 2005 Nov; 280(47):39515-23. PubMed ID: 15998642
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
    Mentrup T; Theodorou K; Cabrera-Cabrera F; Helbig AO; Happ K; Gijbels M; Gradtke AC; Rabe B; Fukumori A; Steiner H; Tholey A; Fluhrer R; Donners M; Schröder B
    J Exp Med; 2019 Apr; 216(4):807-830. PubMed ID: 30819724
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Signal peptide peptidase-like 2 proteases: Regulatory switches or proteasome of the membrane?
    Mentrup T; Schröder B
    Biochim Biophys Acta Mol Cell Res; 2022 Jan; 1869(1):119163. PubMed ID: 34673079
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The role of SPP/SPPL intramembrane proteases in membrane protein homeostasis.
    Mentrup T; Leinung N; Patel M; Fluhrer R; Schröder B
    FEBS J; 2024 Jan; 291(1):25-44. PubMed ID: 37625440
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Signal peptide peptidase and SPP-like proteases - Possible therapeutic targets?
    Mentrup T; Loock AC; Fluhrer R; Schröder B
    Biochim Biophys Acta Mol Cell Res; 2017 Nov; 1864(11 Pt B):2169-2182. PubMed ID: 28624439
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Foamy virus envelope protein is a substrate for signal peptide peptidase-like 3 (SPPL3).
    Voss M; Fukumori A; Kuhn PH; Künzel U; Klier B; Grammer G; Haug-Kröper M; Kremmer E; Lichtenthaler SF; Steiner H; Schröder B; Haass C; Fluhrer R
    J Biol Chem; 2012 Dec; 287(52):43401-9. PubMed ID: 23132852
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Measurement of CD74 N-terminal Fragment Accumulation in Cells Treated with SPPL2a Inhibitor.
    Martínez-Barricarte R; Kong XF; Casanova JL
    Bio Protoc; 2019 Jun; 9(11):e3254. PubMed ID: 33654779
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors.
    Ran Y; Ladd GZ; Ceballos-Diaz C; Jung JI; Greenbaum D; Felsenstein KM; Golde TE
    PLoS One; 2015; 10(6):e0128619. PubMed ID: 26046535
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Discovery of the First Potent, Selective, and Orally Bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) Inhibitor Displaying Pronounced Immunomodulatory Effects In Vivo.
    Velcicky J; Bodendorf U; Rigollier P; Epple R; Beisner DR; Guerini D; Smith P; Liu B; Feifel R; Wipfli P; Aichholz R; Couttet P; Dix I; Widmer T; Wen B; Brandl T
    J Med Chem; 2018 Feb; 61(3):865-880. PubMed ID: 29359565
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.
    Fleck D; Voss M; Brankatschk B; Giudici C; Hampel H; Schwenk B; Edbauer D; Fukumori A; Steiner H; Kremmer E; Haug-Kröper M; Rossner MJ; Fluhrer R; Willem M; Haass C
    J Biol Chem; 2016 Jan; 291(1):318-33. PubMed ID: 26574544
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase.
    Nyborg AC; Ladd TB; Jansen K; Kukar T; Golde TE
    FASEB J; 2006 Aug; 20(10):1671-9. PubMed ID: 16873890
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors.
    Velcicky J; Mathison CJN; Nikulin V; Pflieger D; Epple R; Azimioara M; Cow C; Michellys PY; Rigollier P; Beisner DR; Bodendorf U; Guerini D; Liu B; Wen B; Zaharevitz S; Brandl T
    ACS Med Chem Lett; 2019 Jun; 10(6):887-892. PubMed ID: 31223443
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains.
    Leinung N; Mentrup T; Patel M; Gallagher T; Schröder B
    iScience; 2023 Oct; 26(10):107819. PubMed ID: 37736044
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The transferrin receptor-1 membrane stub undergoes intramembrane proteolysis by signal peptide peptidase-like 2b.
    Zahn C; Kaup M; Fluhrer R; Fuchs H
    FEBS J; 2013 Apr; 280(7):1653-63. PubMed ID: 23384347
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b.
    Fluhrer R; Grammer G; Israel L; Condron MM; Haffner C; Friedmann E; Böhland C; Imhof A; Martoglio B; Teplow DB; Haass C
    Nat Cell Biol; 2006 Aug; 8(8):894-6. PubMed ID: 16829951
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.