320 related articles for article (PubMed ID: 24493214)
1. ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Deshpande RA; Williams GJ; Limbo O; Williams RS; Kuhnlein J; Lee JH; Classen S; Guenther G; Russell P; Tainer JA; Paull TT
EMBO J; 2014 Mar; 33(5):482-500. PubMed ID: 24493214
[TBL] [Abstract][Full Text] [Related]
2. ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.
Hopfner KP
Bioessays; 2014 Dec; 36(12):1170-8. PubMed ID: 25213441
[TBL] [Abstract][Full Text] [Related]
3. A dynamic allosteric pathway underlies Rad50 ABC ATPase function in DNA repair.
Boswell ZK; Rahman S; Canny MD; Latham MP
Sci Rep; 2018 Jan; 8(1):1639. PubMed ID: 29374232
[TBL] [Abstract][Full Text] [Related]
4. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
[TBL] [Abstract][Full Text] [Related]
5. Rad50 ATPase activity is regulated by DNA ends and requires coordination of both active sites.
Deshpande RA; Lee JH; Paull TT
Nucleic Acids Res; 2017 May; 45(9):5255-5268. PubMed ID: 28369545
[TBL] [Abstract][Full Text] [Related]
6. The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.
Lammens K; Bemeleit DJ; Möckel C; Clausing E; Schele A; Hartung S; Schiller CB; Lucas M; Angermüller C; Söding J; Strässer K; Hopfner KP
Cell; 2011 Apr; 145(1):54-66. PubMed ID: 21458667
[TBL] [Abstract][Full Text] [Related]
7. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
Limbo O; Moiani D; Kertokalio A; Wyman C; Tainer JA; Russell P
Nucleic Acids Res; 2012 Dec; 40(22):11435-49. PubMed ID: 23080121
[TBL] [Abstract][Full Text] [Related]
8. Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes.
Bhaskara V; Dupré A; Lengsfeld B; Hopkins BB; Chan A; Lee JH; Zhang X; Gautier J; Zakian V; Paull TT
Mol Cell; 2007 Mar; 25(5):647-61. PubMed ID: 17349953
[TBL] [Abstract][Full Text] [Related]
9. Mre11-Rad50-dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1.
Limbo O; Yamada Y; Russell P
Mol Biol Cell; 2018 Jun; 29(11):1389-1399. PubMed ID: 29851556
[TBL] [Abstract][Full Text] [Related]
10. The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation.
Cassani C; Vertemara J; Bassani M; Marsella A; Tisi R; Zampella G; Longhese MP
Nucleic Acids Res; 2019 Apr; 47(7):3550-3567. PubMed ID: 30698745
[TBL] [Abstract][Full Text] [Related]
11. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
Williams RS; Williams JS; Tainer JA
Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
[TBL] [Abstract][Full Text] [Related]
12. The rad50 signature motif: essential to ATP binding and biological function.
Moncalian G; Lengsfeld B; Bhaskara V; Hopfner KP; Karcher A; Alden E; Tainer JA; Paull TT
J Mol Biol; 2004 Jan; 335(4):937-51. PubMed ID: 14698290
[TBL] [Abstract][Full Text] [Related]
13. Structure of the Rad50 DNA double-strand break repair protein in complex with DNA.
Rojowska A; Lammens K; Seifert FU; Direnberger C; Feldmann H; Hopfner KP
EMBO J; 2014 Dec; 33(23):2847-59. PubMed ID: 25349191
[TBL] [Abstract][Full Text] [Related]
14. ATP hydrolysis by RAD50 protein switches MRE11 enzyme from endonuclease to exonuclease.
Majka J; Alford B; Ausio J; Finn RM; McMurray CT
J Biol Chem; 2012 Jan; 287(4):2328-41. PubMed ID: 22102415
[TBL] [Abstract][Full Text] [Related]
15. LRET-derived HADDOCK structural models describe the conformational heterogeneity required for DNA cleavage by the Mre11-Rad50 DNA damage repair complex.
Canny MD; Latham MP
Elife; 2022 Jan; 11():. PubMed ID: 35084331
[TBL] [Abstract][Full Text] [Related]
16. Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks.
Cassani C; Gobbini E; Wang W; Niu H; Clerici M; Sung P; Longhese MP
PLoS Biol; 2016 Feb; 14(2):e1002387. PubMed ID: 26901759
[TBL] [Abstract][Full Text] [Related]
17. The P. furiosus mre11/rad50 complex promotes 5' strand resection at a DNA double-strand break.
Hopkins BB; Paull TT
Cell; 2008 Oct; 135(2):250-60. PubMed ID: 18957200
[TBL] [Abstract][Full Text] [Related]
18. Dimerization of the Rad50 protein is independent of the conserved hook domain.
Cahill D; Carney JP
Mutagenesis; 2007 Jul; 22(4):269-74. PubMed ID: 17426050
[TBL] [Abstract][Full Text] [Related]
19. Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Williams RS; Dodson GE; Limbo O; Yamada Y; Williams JS; Guenther G; Classen S; Glover JN; Iwasaki H; Russell P; Tainer JA
Cell; 2009 Oct; 139(1):87-99. PubMed ID: 19804755
[TBL] [Abstract][Full Text] [Related]
20. Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
Williams RS; Moncalian G; Williams JS; Yamada Y; Limbo O; Shin DS; Groocock LM; Cahill D; Hitomi C; Guenther G; Moiani D; Carney JP; Russell P; Tainer JA
Cell; 2008 Oct; 135(1):97-109. PubMed ID: 18854158
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
