BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 24494745)

  • 21. Steric parameters, molecular modeling and hydropathic interaction analysis of the pharmacology of para-substituted methcathinone analogues.
    Sakloth F; Kolanos R; Mosier PD; Bonano JS; Banks ML; Partilla JS; Baumann MH; Negus SS; Glennon RA
    Br J Pharmacol; 2015 May; 172(9):2210-8. PubMed ID: 25522019
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structure-Activity Relationships at the Monoamine Transporters for a Novel Series of Modafinil (2-[(diphenylmethyl)sulfinyl]acetamide) Analogues.
    Cao J; Prisinzano TE; Okunola OM; Kopajtic T; Shook M; Katz JL; Newman AH
    ACS Med Chem Lett; 2010 Oct; 2(1):48-52. PubMed ID: 21344069
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Monoamine transporter contributions to l-DOPA effects in hemi-parkinsonian rats.
    Conti MM; Meadows SM; Melikhov-Sosin M; Lindenbach D; Hallmark J; Werner DF; Bishop C
    Neuropharmacology; 2016 Nov; 110(Pt A):125-134. PubMed ID: 27452719
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.
    Dutta AK; Fei XS; Beardsley PM; Newman JL; Reith ME
    J Med Chem; 2001 Mar; 44(6):937-48. PubMed ID: 11300876
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Chlorophenylpiperazine analogues as high affinity dopamine transporter ligands.
    Motel WC; Healy JR; Viard E; Pouw B; Martin K; Matsumoto RR; Coop A
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6920-6922. PubMed ID: 24211020
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Putative drug binding conformations of monoamine transporters.
    Ravna AW; Sylte I; Kristiansen K; Dahl SG
    Bioorg Med Chem; 2006 Feb; 14(3):666-75. PubMed ID: 16216517
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structure-activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter.
    Boos TL; Greiner E; Calhoun WJ; Prisinzano TE; Nightingale B; Dersch CM; Rothman RB; Jacobson AE; Rice KC
    Bioorg Med Chem; 2006 Jun; 14(11):3967-73. PubMed ID: 16563775
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
    Kulkarni SS; Grundt P; Kopajtic T; Katz JL; Newman AH
    J Med Chem; 2004 Jun; 47(13):3388-98. PubMed ID: 15189035
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Structure-activity relationships for a series of (Bis(4-fluorophenyl)methyl)sulfinylethyl-aminopiperidines and -piperidine amines at the dopamine transporter: Bioisosteric replacement of the piperazine improves metabolic stability.
    Giancola JB; Bonifazi A; Cao J; Ku T; Haraczy AJ; Lam J; Rais R; Coggiano MA; Tanda G; Newman AH
    Eur J Med Chem; 2020 Dec; 208():112674. PubMed ID: 32947229
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter.
    Seddik A; Geerke DP; Stockner T; Holy M; Kudlacek O; Cozzi NV; Ruoho AE; Sitte HH; Ecker GF
    Mol Inform; 2017 May; 36(5-6):. PubMed ID: 27860344
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis and monoamine transporter binding properties of 2,3-diaryltropanes.
    Kotturi SV; Jiang S; Chang AC; Abraham P; Navarro HA; Kuhar MJ; Carroll FI
    J Med Chem; 2005 Nov; 48(23):7437-44. PubMed ID: 16279803
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain.
    Murthy V; Davies HM; Hedley SJ; Childers SR
    Biochem Pharmacol; 2007 Jul; 74(2):336-44. PubMed ID: 17540345
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Dopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities.
    Sweeney CG; Tremblay BP; Stockner T; Sitte HH; Melikian HE
    J Biol Chem; 2017 Jan; 292(4):1302-1309. PubMed ID: 27986813
    [TBL] [Abstract][Full Text] [Related]  

  • 34. MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment.
    Verrico CD; Miller GM; Madras BK
    Psychopharmacology (Berl); 2007 Jan; 189(4):489-503. PubMed ID: 16220332
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine.
    Janowsky A; Tosh DK; Eshleman AJ; Jacobson KA
    J Pharmacol Exp Ther; 2016 Apr; 357(1):24-35. PubMed ID: 26813929
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Further characterisation of the interaction of haloperidol metabolites with neurotransmitter transporters in rat neuronal cultures and in transfected COS-7 cells.
    Siebert GA; Pond SM; Bryan-Lluka LJ
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Mar; 361(3):255-64. PubMed ID: 10731037
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
    Kolhatkar RB; Ghorai SK; George C; Reith ME; Dutta AK
    J Med Chem; 2003 May; 46(11):2205-15. PubMed ID: 12747792
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs.
    Han DD; Gu HH
    BMC Pharmacol; 2006 Mar; 6():6. PubMed ID: 16515684
    [TBL] [Abstract][Full Text] [Related]  

  • 39. How to rescue misfolded SERT, DAT and NET: targeting conformational intermediates with atypical inhibitors and partial releasers.
    Bhat S; Newman AH; Freissmuth M
    Biochem Soc Trans; 2019 Jun; 47(3):861-874. PubMed ID: 31064865
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design and synthesis of 2- and 3-substituted-3-phenylpropyl analogs of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: role of amino, fluoro, hydroxyl, methoxyl, methyl, methylene, and oxo substituents on affinity for the dopamine and serotonin transporters.
    Hsin LW; Chang LT; Rothman RB; Dersch CM; Jacobson AE; Rice KC
    J Med Chem; 2008 May; 51(9):2795-806. PubMed ID: 18393401
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.