These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 24496080)

  • 1. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched.
    Busch AM; Galimberti F; Nehls KE; Roengvoraphoj M; Sekula D; Li B; Guo Y; Direnzo J; Fiering SN; Spinella MJ; Robbins DJ; Memoli VA; Freemantle SJ; Dmitrovsky E
    Cancer Biol Ther; 2014 Apr; 15(4):463-72. PubMed ID: 24496080
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL.
    Decker S; Zirlik K; Djebatchie L; Hartmann D; Ihorst G; Schmitt-Graeff A; Herchenbach D; Jumaa H; Warmuth M; Veelken H; Dierks C
    Blood; 2012 Jan; 119(4):997-1007. PubMed ID: 22130798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Adenovirus vector-mediated Gli1 siRNA induces growth inhibition and apoptosis in human pancreatic cancer with Smo-dependent or Smo-independent Hh pathway activation in vitro and in vivo.
    Guo J; Gao J; Li Z; Gong Y; Man X; Jin J; Wu H
    Cancer Lett; 2013 Oct; 339(2):185-94. PubMed ID: 23791879
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells.
    Spicer LJ; Sudo S; Aad PY; Wang LS; Chun SY; Ben-Shlomo I; Klein C; Hsueh AJ
    Reproduction; 2009 Aug; 138(2):329-39. PubMed ID: 19433502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures.
    Cohen JR; Resnick DZ; Niewiadomski P; Dong H; Liau LM; Waschek JA
    BMC Cancer; 2010 Dec; 10():676. PubMed ID: 21143927
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.
    Lee SJ; Do IG; Lee J; Kim KM; Jang J; Sohn I; Kang WK
    Target Oncol; 2013 Dec; 8(4):271-80. PubMed ID: 23371028
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas.
    Gialmanidis IP; Bravou V; Amanetopoulou SG; Varakis J; Kourea H; Papadaki H
    Lung Cancer; 2009 Oct; 66(1):64-74. PubMed ID: 19200615
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of GLI1 gene activation by Patched1.
    Rahnama F; Shimokawa T; Lauth M; Finta C; Kogerman P; Teglund S; Toftgård R; Zaphiropoulos PG
    Biochem J; 2006 Feb; 394(Pt 1):19-26. PubMed ID: 16229683
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway.
    Zhuang Z; Wang K; Cheng X; Qu X; Jiang B; Li Z; Luo J; Shao Z; Duan T
    PLoS One; 2013; 8(7):e67431. PubMed ID: 23861764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.
    Chenna V; Hu C; Pramanik D; Aftab BT; Karikari C; Campbell NR; Hong SM; Zhao M; Rudek MA; Khan SR; Rudin CM; Maitra A
    Mol Cancer Ther; 2012 Jan; 11(1):165-73. PubMed ID: 22027695
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion.
    Bijlsma MF; Spek CA; Zivkovic D; van de Water S; Rezaee F; Peppelenbosch MP
    PLoS Biol; 2006 Jul; 4(8):e232. PubMed ID: 16895439
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.
    Blotta S; Jakubikova J; Calimeri T; Roccaro AM; Amodio N; Azab AK; Foresta U; Mitsiades CS; Rossi M; Todoerti K; Molica S; Morabito F; Neri A; Tagliaferri P; Tassone P; Anderson KC; Munshi NC
    Blood; 2012 Dec; 120(25):5002-13. PubMed ID: 22821765
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
    You M; Varona-Santos J; Singh S; Robbins DJ; Savaraj N; Nguyen DM
    J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ptch2 mediates the Shh response in Ptch1-/- cells.
    Alfaro AC; Roberts B; Kwong L; Bijlsma MF; Roelink H
    Development; 2014 Sep; 141(17):3331-9. PubMed ID: 25085974
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aberrant methylation of the PTCH1 gene promoter region in aberrant crypt foci.
    Peng L; Hu J; Li S; Wang Z; Xia B; Jiang B; Li B; Zhang Y; Wang J; Wang X
    Int J Cancer; 2013 Jan; 132(2):E18-25. PubMed ID: 22945423
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia.
    Moraes RC; Zhang X; Harrington N; Fung JY; Wu MF; Hilsenbeck SG; Allred DC; Lewis MT
    Development; 2007 Mar; 134(6):1231-42. PubMed ID: 17287253
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site.
    Agren M; Kogerman P; Kleman MI; Wessling M; Toftgård R
    Gene; 2004 Apr; 330():101-14. PubMed ID: 15087129
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combination of hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas.
    Bahra M; Kamphues C; Boas-Knoop S; Lippert S; Esendik U; Schüller U; Hartmann W; Waha A; Neuhaus P; Heppner F; Pietsch T; Koch A
    Pancreas; 2012 Mar; 41(2):222-9. PubMed ID: 22076568
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations.
    Galimberti F; Busch AM; Chinyengetere F; Ma T; Sekula D; Memoli VA; Dragnev KH; Liu F; Johnson KC; Guo Y; Freemantle SJ; Andrew AS; Greninger P; Robbins DJ; Settleman J; Benes C; Dmitrovsky E
    Int J Oncol; 2012 Nov; 41(5):1751-61. PubMed ID: 22923130
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.