BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

893 related articles for article (PubMed ID: 24503013)

  • 1. HIF-1α and HIF-2α are critically involved in hypoxia-induced lipid accumulation in hepatocytes through reducing PGC-1α-mediated fatty acid β-oxidation.
    Liu Y; Ma Z; Zhao C; Wang Y; Wu G; Xiao J; McClain CJ; Li X; Feng W
    Toxicol Lett; 2014 Apr; 226(2):117-23. PubMed ID: 24503013
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia exacerbates nonalcoholic fatty liver disease via the HIF-2α/PPARα pathway.
    Chen J; Chen J; Fu H; Li Y; Wang L; Luo S; Lu H
    Am J Physiol Endocrinol Metab; 2019 Oct; 317(4):E710-E722. PubMed ID: 31430204
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia induces dysregulation of lipid metabolism in HepG2 cells via activation of HIF-2α.
    Cao R; Zhao X; Li S; Zhou H; Chen W; Ren L; Zhou X; Zhang H; Shi R
    Cell Physiol Biochem; 2014; 34(5):1427-41. PubMed ID: 25323790
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HIF-1-dependent lipin1 induction prevents excessive lipid accumulation in choline-deficient diet-induced fatty liver.
    Arai T; Tanaka M; Goda N
    Sci Rep; 2018 Sep; 8(1):14230. PubMed ID: 30242180
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes.
    Copple BL; Bustamante JJ; Welch TP; Kim ND; Moon JO
    Liver Int; 2009 Aug; 29(7):1010-21. PubMed ID: 19302442
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo.
    Park MJ; Kim DI; Lim SK; Choi JH; Kim JC; Yoon KC; Lee JB; Lee JH; Han HJ; Choi IP; Kim HC; Park SH
    J Hepatol; 2014 Nov; 61(5):1151-7. PubMed ID: 25003952
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor alpha/retinoid X receptor.
    Belanger AJ; Luo Z; Vincent KA; Akita GY; Cheng SH; Gregory RJ; Jiang C
    Biochem Biophys Res Commun; 2007 Dec; 364(3):567-72. PubMed ID: 17963722
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses.
    Yoon H; Shin SH; Shin DH; Chun YS; Park JW
    Biochem Biophys Res Commun; 2014 Jan; 444(1):36-43. PubMed ID: 24423936
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gly482Ser mutation impairs the effects of peroxisome proliferator-activated receptor γ coactivator-1α on decreasing fat deposition and stimulating phosphoenolpyruvate carboxykinase expression in hepatocytes.
    Chen Y; Mu P; He S; Tang X; Guo X; Li H; Xu H; Woo SL; Qian X; Zeng L; Wu C
    Nutr Res; 2013 Apr; 33(4):332-9. PubMed ID: 23602251
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion.
    Morris EM; Meers GM; Booth FW; Fritsche KL; Hardin CD; Thyfault JP; Ibdah JA
    Am J Physiol Gastrointest Liver Physiol; 2012 Oct; 303(8):G979-92. PubMed ID: 22899824
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.
    Finck BN; Gropler MC; Chen Z; Leone TC; Croce MA; Harris TE; Lawrence JC; Kelly DP
    Cell Metab; 2006 Sep; 4(3):199-210. PubMed ID: 16950137
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased activation of the hypoxia-inducible factor pathway in varicose veins.
    Lim CS; Kiriakidis S; Paleolog EM; Davies AH
    J Vasc Surg; 2012 May; 55(5):1427-39. PubMed ID: 22277691
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bhlhe40 Represses PGC-1α Activity on Metabolic Gene Promoters in Myogenic Cells.
    Chung SY; Kao CH; Villarroya F; Chang HY; Chang HC; Hsiao SP; Liou GG; Chen SL
    Mol Cell Biol; 2015 Jul; 35(14):2518-29. PubMed ID: 25963661
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NcoA2-Dependent Inhibition of HIF-1α Activation Is Regulated via AhR.
    Tsai CH; Li CH; Liao PL; Cheng YW; Lin CH; Huang SH; Kang JJ
    Toxicol Sci; 2015 Dec; 148(2):517-30. PubMed ID: 26350169
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-acid-dependent transcriptional control of interleukin-10 in hepatic cells of rodents.
    Morari J; Torsoni AS; Anhê GF; Roman EA; Cintra DE; Ward LS; Bordin S; Velloso LA
    Metabolism; 2010 Feb; 59(2):215-23. PubMed ID: 19766270
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hepatic lipid metabolic pathways modified by resveratrol in rats fed an obesogenic diet.
    Alberdi G; Rodríguez VM; Macarulla MT; Miranda J; Churruca I; Portillo MP
    Nutrition; 2013 Mar; 29(3):562-7. PubMed ID: 23274094
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
    Nilsson MB; Zage PE; Zeng L; Xu L; Cascone T; Wu HK; Saigal B; Zweidler-McKay PA; Heymach JV
    Oncogene; 2010 May; 29(20):2938-49. PubMed ID: 20208561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HIF-1alpha and -2alpha genes in a hypoxia-sensitive teleost species Megalobrama amblycephala: cDNA cloning, expression and different responses to hypoxia.
    Shen RJ; Jiang XY; Pu JW; Zou SM
    Comp Biochem Physiol B Biochem Mol Biol; 2010 Nov; 157(3):273-80. PubMed ID: 20615476
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular cloning, characterization and expression of two hypoxia-inducible factor alpha subunits, HIF-1alpha and HIF-2alpha, in a hypoxia-tolerant marine teleost, Atlantic croaker (Micropogonias undulatus).
    Rahman MS; Thomas P
    Gene; 2007 Jul; 396(2):273-82. PubMed ID: 17467194
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The HIF-2α/PPARα pathway is essential for liraglutide-alleviated, lipid-induced hepatic steatosis.
    Wang H; Wang L; Li Y; Luo S; Ye J; Lu Z; Li X; Lu H
    Biomed Pharmacother; 2021 Aug; 140():111778. PubMed ID: 34062416
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 45.