BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 24508816)

  • 1. Rapid screening of protein-protein interaction inhibitors using the protease exclusion assay.
    Nirantar SR; Li X; Siau JW; Ghadessy FJ
    Biosens Bioelectron; 2014 Jun; 56():250-7. PubMed ID: 24508816
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular rotors as conditionally fluorescent labels for rapid detection of biomolecular interactions.
    Goh WL; Lee MY; Joseph TL; Quah ST; Brown CJ; Verma C; Brenner S; Ghadessy FJ; Teo YN
    J Am Chem Soc; 2014 Apr; 136(17):6159-62. PubMed ID: 24494589
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phase-separated condensate-aided enrichment of biomolecular interactions for high-throughput drug screening in test tubes.
    Zhou M; Li W; Li J; Xie L; Wu R; Wang L; Fu S; Su W; Hu J; Wang J; Li P
    J Biol Chem; 2020 Aug; 295(33):11420-11434. PubMed ID: 32461254
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Implementation of a 220,000-compound HCS campaign to identify disruptors of the interaction between p53 and hDM2 and characterization of the confirmed hits.
    Dudgeon DD; Shinde S; Hua Y; Shun TY; Lazo JS; Strock CJ; Giuliano KA; Taylor DL; Johnston PA; Johnston PA
    J Biomol Screen; 2010 Aug; 15(7):766-82. PubMed ID: 20639499
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Case Study: discovery of inhibitors of the MDM2-p53 protein-protein interaction.
    Liu L; Bernard D; Wang S
    Methods Mol Biol; 2015; 1278():567-85. PubMed ID: 25859977
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A cell-based high-throughput assay for the screening of small-molecule inhibitors of p53-MDM2 interaction.
    Li J; Zhang S; Gao L; Chen Y; Xie X
    J Biomol Screen; 2011 Apr; 16(4):450-6. PubMed ID: 21471462
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An integrated in silico screening strategy for identifying promising disruptors of p53-MDM2 interaction.
    Sirous H; Chemi G; Campiani G; Brogi S
    Comput Biol Chem; 2019 Dec; 83():107105. PubMed ID: 31473433
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A facile method to screen inhibitors of protein-protein interactions including MDM2-p53 displayed on T7 phage.
    Ishi K; Sugawara F
    Biochem Pharmacol; 2008 May; 75(9):1743-50. PubMed ID: 18384755
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enabling systematic interrogation of protein-protein interactions in live cells with a versatile ultra-high-throughput biosensor platform.
    Mo XL; Luo Y; Ivanov AA; Su R; Havel JJ; Li Z; Khuri FR; Du Y; Fu H
    J Mol Cell Biol; 2016 Jun; 8(3):271-81. PubMed ID: 26578655
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A re-examination of the MDM2/p53 interaction leads to revised design criteria for novel inhibitors.
    Vasilevich NI; Afanasyev II; Kovalskiy DA; Genis DV; Kochubey VS
    Chem Biol Drug Des; 2014 Nov; 84(5):585-92. PubMed ID: 24797588
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode.
    Gessier F; Kallen J; Jacoby E; Chène P; Stachyra-Valat T; Ruetz S; Jeay S; Holzer P; Masuya K; Furet P
    Bioorg Med Chem Lett; 2015 Sep; 25(17):3621-5. PubMed ID: 26141769
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small-molecule MDM2-p53 inhibitors: recent advances.
    Zhang B; Golding BT; Hardcastle IR
    Future Med Chem; 2015; 7(5):631-45. PubMed ID: 25921402
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting the MDM2-p53 protein-protein interaction with prenylchalcones: Synthesis of a small library and evaluation of potential antitumor activity.
    Brandão P; Loureiro JB; Carvalho S; Hamadou MH; Cravo S; Moreira J; Pereira D; Palmeira A; Pinto M; Saraiva L; Cidade H
    Eur J Med Chem; 2018 Aug; 156():711-721. PubMed ID: 30041135
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors.
    Noguchi T; Oishi S; Honda K; Kondoh Y; Saito T; Kubo T; Kaneda M; Ohno H; Osada H; Fujii N
    Bioorg Med Chem Lett; 2013 Jul; 23(13):3802-5. PubMed ID: 23726030
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction.
    Vaupel A; Bold G; De Pover A; Stachyra-Valat T; Lisztwan JH; Kallen J; Masuya K; Furet P
    Bioorg Med Chem Lett; 2014 May; 24(9):2110-4. PubMed ID: 24704029
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Competition NMR for Detection of Hit/Lead Inhibitors of Protein-Protein Interactions.
    Musielak B; Janczyk W; Rodriguez I; Plewka J; Sala D; Magiera-Mularz K; Holak T
    Molecules; 2020 Jul; 25(13):. PubMed ID: 32630327
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A fluorescent-based high-throughput screening assay for small molecules that inhibit the interaction of MdmX with p53.
    Tsuganezawa K; Nakagawa Y; Kato M; Taruya S; Takahashi F; Endoh M; Utata R; Mori M; Ogawa N; Honma T; Yokoyama S; Hashizume Y; Aoki M; Kasai T; Kigawa T; Kojima H; Okabe T; Nagano T; Tanaka A
    J Biomol Screen; 2013 Feb; 18(2):191-8. PubMed ID: 22989451
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AlphaScreen-Based Assays: Ultra-High-Throughput Screening for Small-Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions.
    Yasgar A; Jadhav A; Simeonov A; Coussens NP
    Methods Mol Biol; 2016; 1439():77-98. PubMed ID: 27316989
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.
    Dudgeon DD; Shinde SN; Shun TY; Lazo JS; Strock CJ; Giuliano KA; Taylor DL; Johnston PA; Johnston PA
    Assay Drug Dev Technol; 2010 Aug; 8(4):437-58. PubMed ID: 20662736
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Knowledge-based virtual screening: application to the MDM4/p53 protein-protein interaction.
    Jacoby E; Boettcher A; Mayr LM; Brown N; Jenkins JL; Kallen J; Engeloch C; Schopfer U; Furet P; Masuya K; Lisztwan J
    Methods Mol Biol; 2009; 575():173-94. PubMed ID: 19727615
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.