BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

516 related articles for article (PubMed ID: 24509083)

  • 1. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.
    Qiu H; Lee S; Shang Y; Wang WY; Au KF; Kamiya S; Barmada SJ; Finkbeiner S; Lui H; Carlton CE; Tang AA; Oldham MC; Wang H; Shorter J; Filiano AJ; Roberson ED; Tourtellotte WG; Chen B; Tsai LH; Huang EJ
    J Clin Invest; 2014 Mar; 124(3):981-99. PubMed ID: 24509083
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.
    Pokrishevsky E; Grad LI; Yousefi M; Wang J; Mackenzie IR; Cashman NR
    PLoS One; 2012; 7(4):e35050. PubMed ID: 22493728
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sequestration of PRMT1 and Nd1-L mRNA into ALS-linked FUS mutant R521C-positive aggregates contributes to neurite degeneration upon oxidative stress.
    Jun MH; Ryu HH; Jun YW; Liu T; Li Y; Lim CS; Lee YS; Kaang BK; Jang DJ; Lee JA
    Sci Rep; 2017 Jan; 7():40474. PubMed ID: 28094300
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RBM45 competes with HDAC1 for binding to FUS in response to DNA damage.
    Gong J; Huang M; Wang F; Ma X; Liu H; Tu Y; Xing L; Zhu X; Zheng H; Fang J; Li X; Wang Q; Wang J; Sun Z; Wang X; Wang Y; Guo C; Tang TS
    Nucleic Acids Res; 2017 Dec; 45(22):12862-12876. PubMed ID: 29140459
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.
    Groen EJ; Fumoto K; Blokhuis AM; Engelen-Lee J; Zhou Y; van den Heuvel DM; Koppers M; van Diggelen F; van Heest J; Demmers JA; Kirby J; Shaw PJ; Aronica E; Spliet WG; Veldink JH; van den Berg LH; Pasterkamp RJ
    Hum Mol Genet; 2013 Sep; 22(18):3690-704. PubMed ID: 23681068
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fus gene mutations in familial and sporadic amyotrophic lateral sclerosis.
    Rademakers R; Stewart H; Dejesus-Hernandez M; Krieger C; Graff-Radford N; Fabros M; Briemberg H; Cashman N; Eisen A; Mackenzie IR
    Muscle Nerve; 2010 Aug; 42(2):170-6. PubMed ID: 20544928
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.
    Wang WY; Pan L; Su SC; Quinn EJ; Sasaki M; Jimenez JC; Mackenzie IR; Huang EJ; Tsai LH
    Nat Neurosci; 2013 Oct; 16(10):1383-91. PubMed ID: 24036913
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
    Daigle JG; Lanson NA; Smith RB; Casci I; Maltare A; Monaghan J; Nichols CD; Kryndushkin D; Shewmaker F; Pandey UB
    Hum Mol Genet; 2013 Mar; 22(6):1193-205. PubMed ID: 23257289
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.
    Lagier-Tourenne C; Polymenidou M; Hutt KR; Vu AQ; Baughn M; Huelga SC; Clutario KM; Ling SC; Liang TY; Mazur C; Wancewicz E; Kim AS; Watt A; Freier S; Hicks GG; Donohue JP; Shiue L; Bennett CF; Ravits J; Cleveland DW; Yeo GW
    Nat Neurosci; 2012 Nov; 15(11):1488-97. PubMed ID: 23023293
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Autophagy regulates amyotrophic lateral sclerosis-linked fused in sarcoma-positive stress granules in neurons.
    Ryu HH; Jun MH; Min KJ; Jang DJ; Lee YS; Kim HK; Lee JA
    Neurobiol Aging; 2014 Dec; 35(12):2822-2831. PubMed ID: 25216585
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: two distinct patterns correlating with disease severity and mutation.
    Mackenzie IR; Ansorge O; Strong M; Bilbao J; Zinman L; Ang LC; Baker M; Stewart H; Eisen A; Rademakers R; Neumann M
    Acta Neuropathol; 2011 Jul; 122(1):87-98. PubMed ID: 21604077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
    Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A
    Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition.
    Pelaez MC; Desmeules A; Gelon PA; Glasson B; Marcadet L; Rodgers A; Phaneuf D; Pozzi S; Dutchak PA; Julien JP; Sephton CF
    Acta Neuropathol Commun; 2023 Nov; 11(1):182. PubMed ID: 37974279
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.
    Wächter N; Storch A; Hermann A
    Amyotroph Lateral Scler Frontotemporal Degener; 2015; 16(7-8):431-41. PubMed ID: 26174443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.
    Scekic-Zahirovic J; Oussini HE; Mersmann S; Drenner K; Wagner M; Sun Y; Allmeroth K; Dieterlé S; Sinniger J; Dirrig-Grosch S; René F; Dormann D; Haass C; Ludolph AC; Lagier-Tourenne C; Storkebaum E; Dupuis L
    Acta Neuropathol; 2017 Jun; 133(6):887-906. PubMed ID: 28243725
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways.
    Blokhuis AM; Koppers M; Groen EJN; van den Heuvel DMA; Dini Modigliani S; Anink JJ; Fumoto K; van Diggelen F; Snelting A; Sodaar P; Verheijen BM; Demmers JAA; Veldink JH; Aronica E; Bozzoni I; den Hertog J; van den Berg LH; Pasterkamp RJ
    Acta Neuropathol; 2016 Aug; 132(2):175-196. PubMed ID: 27164932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
    Vance C; Rogelj B; Hortobágyi T; De Vos KJ; Nishimura AL; Sreedharan J; Hu X; Smith B; Ruddy D; Wright P; Ganesalingam J; Williams KL; Tripathi V; Al-Saraj S; Al-Chalabi A; Leigh PN; Blair IP; Nicholson G; de Belleroche J; Gallo JM; Miller CC; Shaw CE
    Science; 2009 Feb; 323(5918):1208-1211. PubMed ID: 19251628
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ALS mutations in TLS/FUS disrupt target gene expression.
    Coady TH; Manley JL
    Genes Dev; 2015 Aug; 29(16):1696-706. PubMed ID: 26251528
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis.
    Shang Y; Huang EJ
    Brain Res; 2016 Sep; 1647():65-78. PubMed ID: 27033831
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FUS/TLS-immunoreactive neuronal and glial cell inclusions increase with disease duration in familial amyotrophic lateral sclerosis with an R521C FUS/TLS mutation.
    Suzuki N; Kato S; Kato M; Warita H; Mizuno H; Kato M; Shimakura N; Akiyama H; Kobayashi Z; Konno H; Aoki M
    J Neuropathol Exp Neurol; 2012 Sep; 71(9):779-88. PubMed ID: 22878663
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.