These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

93 related articles for article (PubMed ID: 2451915)

  • 1. Conformation and sandwiching of bases by azido groups in the crystal structure of 3'-azido-3'-deoxy-thymidine (AZT), an antiviral agent that inhibits HIV reverse transcriptase.
    Parthasarathy R; Kim H
    Biochem Biophys Res Commun; 1988 Apr; 152(1):351-8. PubMed ID: 2451915
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformational properties of 3'-azido-3'deoxy-thymidine (AZT), an inhibitor of HIV reverse transcriptase.
    Herzyk P; Beveridge A; Neidle S
    Biochem Biophys Res Commun; 1987 Jun; 145(3):1356-61. PubMed ID: 2440430
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.
    Boyer PL; Sarafianos SG; Arnold E; Hughes SH
    J Virol; 2001 May; 75(10):4832-42. PubMed ID: 11312355
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate.
    Mazumder A; Cooney D; Agbaria R; Gupta M; Pommier Y
    Proc Natl Acad Sci U S A; 1994 Jun; 91(13):5771-5. PubMed ID: 8016063
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
    Periclou AP; Nandy P; Avramis VI
    In Vivo; 2000; 14(3):377-88. PubMed ID: 10904870
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of 5'-triphosphate mimics (P3Ms) of 3'-azido-3',5'-dideoxythymidine and 3',5'-dideoxy-5'-difluoromethylenethymidine as HIV-1 reverse transcriptase inhibitors.
    Rajwanshi VK; Prhavc M; Fagan P; Brooks JL; Hurd T; Cook PD; Wang G
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(3):179-89. PubMed ID: 15892257
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Different patterns of inhibition of avian myeloblastosis virus reverse transcriptase activity by 3'-azido-3'-deoxythymidine 5'-triphosphate and its threo isomer.
    Eriksson B; Vrang L; Bazin H; Chattopadhyaya J; Oberg B
    Antimicrob Agents Chemother; 1987 Apr; 31(4):600-4. PubMed ID: 2440379
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of the reverse transcriptase from HIV by 3'-azido-3'-deoxythymidine triphosphate and its threo analogue.
    Vrang L; Bazin H; Remaud G; Chattopadhyaya J; Oberg B
    Antiviral Res; 1987 Mar; 7(3):139-49. PubMed ID: 2440380
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
    Kerr SG; Anderson KS
    Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases.
    White EL; Parker WB; Macy LJ; Shaddix SC; McCaleb G; Secrist JA; Vince R; Shannon WM
    Biochem Biophys Res Commun; 1989 Jun; 161(2):393-8. PubMed ID: 2472136
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective and synergistic inhibition of human immunodeficiency virus type 1 reverse transcriptase by a non-nucleoside inhibitor, MKC-442.
    Yuasa S; Sadakata Y; Takashima H; Sekiya K; Inouye N; Ubasawa M; Baba M
    Mol Pharmacol; 1993 Oct; 44(4):895-900. PubMed ID: 7694070
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of the RNase H activity of HIV reverse transcriptase by azidothymidylate.
    Tan CK; Civil R; Mian AM; So AG; Downey KM
    Biochemistry; 1991 May; 30(20):4831-5. PubMed ID: 1709809
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1.
    Boyer PL; Sarafianos SG; Arnold E; Hughes SH
    J Virol; 2002 Apr; 76(7):3248-56. PubMed ID: 11884549
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitory effect of N3-methyl derivative of 3'-azido-3'-deoxythymidine 5'-triphosphate on the activity of HIV-1 reverse transcriptase.
    Nakane H; Suzuki A; Nakata Y; Kitade Y; Hirota K; Maki Y; Ono K
    Nucleic Acids Symp Ser; 1991; (25):27-8. PubMed ID: 1726810
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NMR study of dideoxynucleotides with anti-human immunodeficiency virus (HIV) activity.
    Reddy DV; Jagannadh B; Kunwar AC
    J Biochem Biophys Methods; 1996 Feb; 31(3-4):113-21. PubMed ID: 8675954
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure and conformational analysis of the anti-HIV reverse transcriptase inhibitor AZT using MP2 and DFT methods. Differences with the natural nucleoside thymidine. Simulation of the 1st phosphorylation step with ATP.
    Palafox MA
    Phys Chem Chem Phys; 2014 Dec; 16(45):24763-83. PubMed ID: 25317835
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reduction of 3'-azido-3'-deoxythymidine (AZT) and AZT nucleotides by thiols. Kinetics and product identification.
    Reardon JE; Crouch RC; St John-Williams L
    J Biol Chem; 1994 Jun; 269(23):15999-6008. PubMed ID: 8206896
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinetics and inhibition of reverse transcriptase from human and simian immunodeficiency viruses.
    Wu JC; Chernow M; Boehme RE; Suttmann RT; McRoberts MJ; Prisbe EJ; Matthews TR; Marx PA; Chuang RY; Chen MS
    Antimicrob Agents Chemother; 1988 Dec; 32(12):1887-90. PubMed ID: 2469388
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and in vitro activity of long-chain 5'-O-[(alkoxycarbonyl)phosphinyl]-3'-azido-3'-deoxythymidines against wild-type and AZT- and foscarnet-resistant strains of HIV-1.
    Rosowsky A; Fu H; Pai N; Mellors J; Richman DD; Hostetler KY
    J Med Chem; 1997 Aug; 40(16):2482-90. PubMed ID: 9258355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An analysis of the inhibition of replication of HIV and MuLV by some 3'-blocked pyrimidine analogs.
    Bazin H; Chattopadhyaya J; Datema R; Ericson AC; Gilljam G; Johansson NG; Hansen J; Koshida R; Moelling K; Oberg B
    Biochem Pharmacol; 1989 Jan; 38(1):109-19. PubMed ID: 2462876
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.