190 related articles for article (PubMed ID: 24523115)
1. Enzyme kinetics of uridine diphosphate glucuronosyltransferases (UGTs).
Zhou J; Miners JO
Methods Mol Biol; 2014; 1113():203-28. PubMed ID: 24523115
[TBL] [Abstract][Full Text] [Related]
2. Enzyme Kinetics of Uridine Diphosphate Glucuronosyltransferases (UGTs).
Zhou J; Argikar UA; Miners JO
Methods Mol Biol; 2021; 2342():301-338. PubMed ID: 34272700
[TBL] [Abstract][Full Text] [Related]
3. The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro-in vivo extrapolation of drug clearance and drug-drug interaction potential.
Miners JO; Mackenzie PI; Knights KM
Drug Metab Rev; 2010 Feb; 42(1):196-208. PubMed ID: 19795925
[TBL] [Abstract][Full Text] [Related]
4. Glucuronidation of haloperidol by rat liver microsomes: involvement of family 2 UDP-glucuronosyltransferases.
Narayanan R; LeDuc B; Williams DA
Life Sci; 2004 Apr; 74(20):2527-39. PubMed ID: 15010263
[TBL] [Abstract][Full Text] [Related]
5. In vitro-in vivo correlation for drugs and other compounds eliminated by glucuronidation in humans: pitfalls and promises.
Miners JO; Knights KM; Houston JB; Mackenzie PI
Biochem Pharmacol; 2006 May; 71(11):1531-9. PubMed ID: 16455060
[TBL] [Abstract][Full Text] [Related]
6. Targeted screen for human UDP-glucuronosyltransferases inhibitors and the evaluation of potential drug-drug interactions with zafirlukast.
Oda S; Fujiwara R; Kutsuno Y; Fukami T; Itoh T; Yokoi T; Nakajima M
Drug Metab Dispos; 2015 Jun; 43(6):812-8. PubMed ID: 25834030
[TBL] [Abstract][Full Text] [Related]
7. UDP-glucuronic acid binds first and the aglycone substrate binds second to form a ternary complex in UGT1A9-catalyzed reactions, in both the presence and absence of bovine serum albumin.
Manevski N; Yli-Kauhaluoma J; Finel M
Drug Metab Dispos; 2012 Nov; 40(11):2192-203. PubMed ID: 22912433
[TBL] [Abstract][Full Text] [Related]
8. The effects of UDP-sugars, UDP and Mg
Walia G; Smith AD; Riches Z; Collier AC; Coughtrie MWH
Xenobiotica; 2018 Sep; 48(9):882-890. PubMed ID: 28868965
[TBL] [Abstract][Full Text] [Related]
9. A broad-spectrum substrate for the human UDP-glucuronosyltransferases and its use for investigating glucuronidation inhibitors.
Zhou QH; Qin WW; Finel M; He QQ; Tu DZ; Wang CR; Ge GB
Int J Biol Macromol; 2021 Jun; 180():252-261. PubMed ID: 33741369
[TBL] [Abstract][Full Text] [Related]
10. Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
Shiraga T; Yajima K; Suzuki K; Suzuki K; Hashimoto T; Iwatsubo T; Miyashita A; Usui T
Drug Metab Dispos; 2012 Feb; 40(2):276-82. PubMed ID: 22031623
[TBL] [Abstract][Full Text] [Related]
11. Validated assay for studying activity profiles of human liver UGTs after drug exposure: inhibition and induction studies.
Donato MT; Montero S; Castell JV; Gómez-Lechón MJ; Lahoz A
Anal Bioanal Chem; 2010 Mar; 396(6):2251-63. PubMed ID: 20145913
[TBL] [Abstract][Full Text] [Related]
12. The glucuronidation of R- and S-lorazepam: human liver microsomal kinetics, UDP-glucuronosyltransferase enzyme selectivity, and inhibition by drugs.
Uchaipichat V; Suthisisang C; Miners JO
Drug Metab Dispos; 2013 Jun; 41(6):1273-84. PubMed ID: 23554428
[TBL] [Abstract][Full Text] [Related]
13. Involvement of UDP-glucuronosyltransferases UGT1A9 and UGT2B7 in ethanol glucuronidation, and interactions with common drugs of abuse.
Al Saabi A; Allorge D; Sauvage FL; Tournel G; Gaulier JM; Marquet P; Picard N
Drug Metab Dispos; 2013 Mar; 41(3):568-74. PubMed ID: 23230132
[TBL] [Abstract][Full Text] [Related]
14. Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes.
Chen A; Zhou X; Cheng Y; Tang S; Liu M; Wang X
Toxicol Lett; 2018 Oct; 295():379-389. PubMed ID: 30036684
[TBL] [Abstract][Full Text] [Related]
15. Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential implications in acetaminophen-induced hepatotoxicity.
Mutlib AE; Goosen TC; Bauman JN; Williams JA; Kulkarni S; Kostrubsky S
Chem Res Toxicol; 2006 May; 19(5):701-9. PubMed ID: 16696573
[TBL] [Abstract][Full Text] [Related]
16. Altered AZT (3'-azido-3'-deoxythymidine) glucuronidation kinetics in liver microsomes as an explanation for underprediction of in vivo clearance: comparison to hepatocytes and effect of incubation environment.
Engtrakul JJ; Foti RS; Strelevitz TJ; Fisher MB
Drug Metab Dispos; 2005 Nov; 33(11):1621-7. PubMed ID: 16049128
[TBL] [Abstract][Full Text] [Related]
17. Everolimus-inhibited multiple isoforms of UDP-glucuronosyltransferases (UGTs).
Du Z; Wang G; Cao YF; Hu CM; Yang K; Liu YZ; Zhang CZ; Zhang WH; Zhu ZT; Sun HZ; Sun XY; Hong M; Fang ZZ
Xenobiotica; 2018 May; 48(5):452-458. PubMed ID: 28548030
[TBL] [Abstract][Full Text] [Related]
18. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
Fujiwara R; Nakajima M; Yamanaka H; Katoh M; Yokoi T
Drug Metab Dispos; 2008 Feb; 36(2):361-7. PubMed ID: 17998297
[TBL] [Abstract][Full Text] [Related]
19. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
Ma L; Sun J; Peng Y; Zhang R; Shao F; Hu X; Zhu J; Wang X; Cheng X; Zhu Y; Wan P; Feng D; Wu H; Wang G
Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
[TBL] [Abstract][Full Text] [Related]
20. Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone) "probes" for human udp-glucuronosyltransferases.
Uchaipichat V; Mackenzie PI; Elliot DJ; Miners JO
Drug Metab Dispos; 2006 Mar; 34(3):449-56. PubMed ID: 16381668
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
