BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 24528253)

  • 1. Short communication: SAHA (vorinostat) induces CDK9 Thr-186 (T-loop) phosphorylation in resting CD4+ T cells: implications for reactivation of latent HIV.
    Ramakrishnan R; Liu H; Rice AP
    AIDS Res Hum Retroviruses; 2015 Jan; 31(1):137-41. PubMed ID: 24528253
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Short Communication: The Broad-Spectrum Histone Deacetylase Inhibitors Vorinostat and Panobinostat Activate Latent HIV in CD4(+) T Cells In Part Through Phosphorylation of the T-Loop of the CDK9 Subunit of P-TEFb.
    Jamaluddin MS; Hu PW; Jan Y; Siwak EB; Rice AP
    AIDS Res Hum Retroviruses; 2016 Feb; 32(2):169-73. PubMed ID: 26727990
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expression.
    Budhiraja S; Ramakrishnan R; Rice AP
    Retrovirology; 2012 Jun; 9():52. PubMed ID: 22727189
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.
    Mbonye UR; Gokulrangan G; Datt M; Dobrowolski C; Cooper M; Chance MR; Karn J
    PLoS Pathog; 2013; 9(5):e1003338. PubMed ID: 23658523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells.
    Budhiraja S; Famiglietti M; Bosque A; Planelles V; Rice AP
    J Virol; 2013 Jan; 87(2):1211-20. PubMed ID: 23152527
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells.
    Sung TL; Rice AP
    Retrovirology; 2006 Oct; 3():66. PubMed ID: 17014716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription.
    Bartholomeeusen K; Fujinaga K; Xiang Y; Peterlin BM
    J Biol Chem; 2013 May; 288(20):14400-14407. PubMed ID: 23539624
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The HIV-1 Tat Protein: Mechanism of Action and Target for HIV-1 Cure Strategies.
    Rice AP
    Curr Pharm Des; 2017; 23(28):4098-4102. PubMed ID: 28677507
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells to HIV by increasing the kinetics and efficiency of postentry viral events.
    Lucera MB; Tilton CA; Mao H; Dobrowolski C; Tabler CO; Haqqani AA; Karn J; Tilton JC
    J Virol; 2014 Sep; 88(18):10803-12. PubMed ID: 25008921
    [TBL] [Abstract][Full Text] [Related]  

  • 10. T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway.
    Kim YK; Mbonye U; Hokello J; Karn J
    J Mol Biol; 2011 Jul; 410(5):896-916. PubMed ID: 21763495
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes.
    Ramakrishnan R; Dow EC; Rice AP
    J Leukoc Biol; 2009 Dec; 86(6):1345-50. PubMed ID: 19741158
    [TBL] [Abstract][Full Text] [Related]  

  • 12. T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes.
    Dow EC; Liu H; Rice AP
    J Cell Physiol; 2010 Jul; 224(1):84-93. PubMed ID: 20201073
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BET inhibitors RVX-208 and PFI-1 reactivate HIV-1 from latency.
    Lu P; Shen Y; Yang H; Wang Y; Jiang Z; Yang X; Zhong Y; Pan H; Xu J; Lu H; Zhu H
    Sci Rep; 2017 Nov; 7(1):16646. PubMed ID: 29192216
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heat Shock Protein 90 Facilitates Latent HIV Reactivation through Maintaining the Function of Positive Transcriptional Elongation Factor b (p-TEFb) under Proteasome Inhibition.
    Pan XY; Zhao W; Wang CY; Lin J; Zeng XY; Ren RX; Wang K; Xun TR; Shai Y; Liu SW
    J Biol Chem; 2016 Dec; 291(50):26177-26187. PubMed ID: 27799305
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1.
    Tyagi M; Iordanskiy S; Ammosova T; Kumari N; Smith K; Breuer D; Ilatovskiy AV; Kont YS; Ivanov A; Üren A; Kovalskyy D; Petukhov M; Kashanchi F; Nekhai S
    Retrovirology; 2015 Jul; 12():63. PubMed ID: 26178009
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HTLV-1 Tax activates HIV-1 transcription in latency models.
    Geddes VEV; José DP; Leal FE; Nixon DF; Tanuri A; Aguiar RS
    Virology; 2017 Apr; 504():45-51. PubMed ID: 28152383
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantification of HIV-1 latency reversal in resting CD4+ T cells from patients on suppressive antiretroviral therapy.
    Cillo AR; Sobolewski MD; Bosch RJ; Fyne E; Piatak M; Coffin JM; Mellors JW
    Proc Natl Acad Sci U S A; 2014 May; 111(19):7078-83. PubMed ID: 24706775
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1).
    Chiu YL; Cao H; Jacque JM; Stevenson M; Rana TM
    J Virol; 2004 Mar; 78(5):2517-29. PubMed ID: 14963154
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of novel CDK9 and Cyclin T1-associated protein complexes (CCAPs) whose siRNA depletion enhances HIV-1 Tat function.
    Ramakrishnan R; Liu H; Donahue H; Malovannaya A; Qin J; Rice AP
    Retrovirology; 2012 Oct; 9():90. PubMed ID: 23110726
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of TAK/P-TEFb in CD4+ T lymphocytes and macrophages.
    Rice AP; Herrmann CH
    Curr HIV Res; 2003 Oct; 1(4):395-404. PubMed ID: 15049426
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.