BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

90 related articles for article (PubMed ID: 24531228)

  • 1. Synthesis of (3-hydroxy-pyrazolin-5-yl)glycine based ligands interacting with ionotropic glutamate receptors.
    Pinto A; Tamborini L; Mastronardi F; Ettari R; Safoz Y; Bunch L; Nielsen B; Jensen AA; De Micheli C; Conti P
    Eur J Med Chem; 2014 Mar; 75():151-8. PubMed ID: 24531228
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid.
    Pinto A; Conti P; De Amici M; Tamborini L; Madsen U; Nielsen B; Christesen T; Bräuner-Osborne H; De Micheli C
    J Med Chem; 2008 Apr; 51(7):2311-5. PubMed ID: 18338843
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heteroaryl analogues of AMPA. Synthesis and quantitative structure-activity relationships.
    Bang-Andersen B; Lenz SM; Skjaerbaek N; Søby KK; Hansen HO; Ebert B; Bøgesø KP; Krogsgaard-Larsen P
    J Med Chem; 1997 Aug; 40(18):2831-42. PubMed ID: 9288165
    [TBL] [Abstract][Full Text] [Related]  

  • 4. (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.
    Brehm L; Greenwood JR; Hansen KB; Nielsen B; Egebjerg J; Stensbøl TB; Bräuner-Osborne H; Sløk FA; Kronborg TT; Krogsgaard-Larsen P
    J Med Chem; 2003 Apr; 46(8):1350-8. PubMed ID: 12672235
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors.
    Pinto A; Conti P; Grazioso G; Tamborini L; Madsen U; Nielsen B; De Micheli C
    Eur J Med Chem; 2011 Feb; 46(2):787-93. PubMed ID: 21220180
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 1,2,4-Benzothiadiazine-1,1-dioxide derivatives as ionotropic glutamate receptor ligands: synthesis and structure-activity relationships.
    Varano F; Catarzi D; Colotta V; Squarcialupi L; Matucci R
    Arch Pharm (Weinheim); 2014 Nov; 347(11):777-85. PubMed ID: 25204434
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters.
    Assaf Z; Larsen AP; Venskutonytė R; Han L; Abrahamsen B; Nielsen B; Gajhede M; Kastrup JS; Jensen AA; Pickering DS; Frydenvang K; Gefflaut T; Bunch L
    J Med Chem; 2013 Feb; 56(4):1614-28. PubMed ID: 23414088
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rational design, synthesis and pharmacological evaluation of the (2R)- and (2S)-stereoisomers of 3-(2-carboxypyrrolidinyl)-2-methyl acetic acid as ligands for the ionotropic glutamate receptors.
    Rasmussen JL; Storgaard M; Pickering DS; Bunch L
    ChemMedChem; 2011 Mar; 6(3):498-504. PubMed ID: 21268287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, molecular modeling studies, and preliminary pharmacological characterization of all possible 2-(2'-sulfonocyclopropyl)glycine stereoisomers as conformationally constrained L-homocysteic acid analogs.
    Pellicciari R; Marinozzi M; Macchiarulo A; Fulco MC; Gafarova J; Serpi M; Giorgi G; Nielsen S; Thomsen C
    J Med Chem; 2007 Sep; 50(19):4630-41. PubMed ID: 17725337
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5-(N-oxyaza)-7-substituted-1,4-dihydroquinoxaline-2,3-diones: novel, systemically active and broad spectrum antagonists for NMDA/glycine, AMPA, and kainate receptors.
    Cai SX; Huang JC; Espitia SA; Tran M; Ilyin VI; Hawkinson JE; Woodward RM; Weber E; Keana JF
    J Med Chem; 1997 Oct; 40(22):3679-86. PubMed ID: 9357535
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
    Clausen RP; Hansen KB; Calí P; Nielsen B; Greenwood JR; Begtrup M; Egebjerg J; Bräuner-Osborne H
    Eur J Pharmacol; 2004 Sep; 499(1-2):35-44. PubMed ID: 15363949
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonists.
    Penning TD; Khilevich A; Chen BB; Russell MA; Boys ML; Wang Y; Duffin T; Engleman VW; Finn MB; Freeman SK; Hanneke ML; Keene JL; Klover JA; Nickols GA; Nickols MA; Rader RK; Settle SL; Shannon KE; Steininger CN; Westlin MM; Westlin WF
    Bioorg Med Chem Lett; 2006 Jun; 16(12):3156-61. PubMed ID: 16621534
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Diversity Oriented Synthesis Approach to New 2,3-
    Kayser S; Temperini P; Poulie CBM; Staudt M; Nielsen B; Pickering DS; Bunch L
    ACS Chem Neurosci; 2020 Mar; 11(5):702-714. PubMed ID: 32069018
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation and synthesis of aminohydroxyisoxazoles and pyrazoles as potential glycine agonists.
    Drummond J; Johnson G; Nickell DG; Ortwine DF; Bruns RF; Welbaum B
    J Med Chem; 1989 Sep; 32(9):2116-28. PubMed ID: 2549245
    [TBL] [Abstract][Full Text] [Related]  

  • 15. AMPA receptor agonists: resolution, configurational assignment, and pharmacology of (+)-(S)- and (-)-(R)-2-amino-3-[3-hydroxy-5-(2-pyridyl)-isoxazol-4-yl]-propionic acid (2-Py-AMPA).
    Johansen TN; Ebert B; Falch E; Krogsgaard-Larsen P
    Chirality; 1997; 9(3):274-80. PubMed ID: 9176992
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of analogues of 7-chloro-4,5-dihydro-4- oxo-8-(1,2,4-triazol-4-yl)-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylic acid (TQX-173) as novel selective AMPA receptor antagonists.
    Catarzi D; Colotta V; Varano F; Calabri FR; Filacchioni G; Galli A; Costagli C; Carlà V
    J Med Chem; 2004 Jan; 47(1):262-72. PubMed ID: 14695840
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships.
    Falch E; Brehm L; Mikkelsen I; Johansen TN; Skjaerbaek N; Nielsen B; Stensbøl TB; Ebert B; Krogsgaard-Larsen P
    J Med Chem; 1998 Jul; 41(14):2513-23. PubMed ID: 9651156
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel AMPA and kainate receptor antagonists containing the pyrazolo[1,5-c]quinazoline ring system: Synthesis and structure-activity relationships.
    Varano F; Catarzi D; Colotta V; Lenzi O; Filacchioni G; Galli A; Costagli C
    Bioorg Med Chem; 2008 Mar; 16(5):2617-26. PubMed ID: 18063372
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Subtype selectivity and flexibility of ionotropic glutamate receptors upon antagonist ligand binding.
    Pentikäinen U; Settimo L; Johnson MS; Pentikäinen OT
    Org Biomol Chem; 2006 Mar; 4(6):1058-70. PubMed ID: 16525550
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kynurenic acid analogues with improved affinity and selectivity for the glycine site on the N-methyl-D-aspartate receptor from rat brain.
    Foster AC; Kemp JA; Leeson PD; Grimwood S; Donald AE; Marshall GR; Priestley T; Smith JD; Carling RW
    Mol Pharmacol; 1992 May; 41(5):914-22. PubMed ID: 1375317
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.