BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

593 related articles for article (PubMed ID: 24531984)

  • 1. Targeting glutamine transport to suppress melanoma cell growth.
    Wang Q; Beaumont KA; Otte NJ; Font J; Bailey CG; van Geldermalsen M; Sharp DM; Tiffen JC; Ryan RM; Jormakka M; Haass NK; Rasko JE; Holst J
    Int J Cancer; 2014 Sep; 135(5):1060-71. PubMed ID: 24531984
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development.
    Wang Q; Hardie RA; Hoy AJ; van Geldermalsen M; Gao D; Fazli L; Sadowski MC; Balaban S; Schreuder M; Nagarajah R; Wong JJ; Metierre C; Pinello N; Otte NJ; Lehman ML; Gleave M; Nelson CC; Bailey CG; Ritchie W; Rasko JE; Holst J
    J Pathol; 2015 Jul; 236(3):278-89. PubMed ID: 25693838
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeted Suppression and Knockout of ASCT2 or LAT1 in Epithelial and Mesenchymal Human Liver Cancer Cells Fail to Inhibit Growth.
    Bothwell PJ; Kron CD; Wittke EF; Czerniak BN; Bode BP
    Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30029480
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5).
    Cormerais Y; Massard PA; Vucetic M; Giuliano S; Tambutté E; Durivault J; Vial V; Endou H; Wempe MF; Parks SK; Pouyssegur J
    J Biol Chem; 2018 Feb; 293(8):2877-2887. PubMed ID: 29326164
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways.
    van Geldermalsen M; Quek LE; Turner N; Freidman N; Pang A; Guan YF; Krycer JR; Ryan R; Wang Q; Holst J
    BMC Cancer; 2018 Jun; 18(1):689. PubMed ID: 29940911
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting of glutamine transporter ASCT2 and glutamine synthetase suppresses gastric cancer cell growth.
    Ye J; Huang Q; Xu J; Huang J; Wang J; Zhong W; Chen W; Lin X; Lin X
    J Cancer Res Clin Oncol; 2018 May; 144(5):821-833. PubMed ID: 29435734
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of glucose metabolism prevents glycosylation of the glutamine transporter ASCT2 and promotes compensatory LAT1 upregulation in leukemia cells.
    Polet F; Martherus R; Corbet C; Pinto A; Feron O
    Oncotarget; 2016 Jul; 7(29):46371-46383. PubMed ID: 27344174
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SLC1A5 Silencing Inhibits Esophageal Cancer Growth via Cell Cycle Arrest and Apoptosis.
    Lin J; Yang T; Peng Z; Xiao H; Jiang N; Zhang L; Ca D; Wu P; Pan Q
    Cell Physiol Biochem; 2018; 48(1):397. PubMed ID: 30071532
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High-affinity glutamate transporter GLAST/EAAT1 regulates cell surface expression of glutamine/neutral amino acid transporter ASCT2 in human fetal astrocytes.
    Gegelashvili M; Rodriguez-Kern A; Pirozhkova I; Zhang J; Sung L; Gegelashvili G
    Neurochem Int; 2006; 48(6-7):611-5. PubMed ID: 16516348
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.
    Nakaya M; Xiao Y; Zhou X; Chang JH; Chang M; Cheng X; Blonska M; Lin X; Sun SC
    Immunity; 2014 May; 40(5):692-705. PubMed ID: 24792914
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer.
    van Geldermalsen M; Wang Q; Nagarajah R; Marshall AD; Thoeng A; Gao D; Ritchie W; Feng Y; Bailey CG; Deng N; Harvey K; Beith JM; Selinger CI; O'Toole SA; Rasko JE; Holst J
    Oncogene; 2016 Jun; 35(24):3201-8. PubMed ID: 26455325
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development.
    Wang Q; Tiffen J; Bailey CG; Lehman ML; Ritchie W; Fazli L; Metierre C; Feng YJ; Li E; Gleave M; Buchanan G; Nelson CC; Rasko JE; Holst J
    J Natl Cancer Inst; 2013 Oct; 105(19):1463-73. PubMed ID: 24052624
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.
    Nagamori S; Wiriyasermkul P; Okuda S; Kojima N; Hari Y; Kiyonaka S; Mori Y; Tominaga H; Ohgaki R; Kanai Y
    Amino Acids; 2016 Apr; 48(4):1045-1058. PubMed ID: 26724922
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime?
    Fuchs BC; Bode BP
    Semin Cancer Biol; 2005 Aug; 15(4):254-66. PubMed ID: 15916903
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.
    Willems L; Jacque N; Jacquel A; Neveux N; Maciel TT; Lambert M; Schmitt A; Poulain L; Green AS; Uzunov M; Kosmider O; Radford-Weiss I; Moura IC; Auberger P; Ifrah N; Bardet V; Chapuis N; Lacombe C; Mayeux P; Tamburini J; Bouscary D
    Blood; 2013 Nov; 122(20):3521-32. PubMed ID: 24014241
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of Amino Acid Transporters (LAT1 and ASCT2) in Patients with Stage III/IV Laryngeal Squamous Cell Carcinoma.
    Nikkuni O; Kaira K; Toyoda M; Shino M; Sakakura K; Takahashi K; Tominaga H; Oriuchi N; Suzuki M; Iijima M; Asao T; Nishiyama M; Nagamori S; Kanai Y; Oyama T; Chikamatsu K
    Pathol Oncol Res; 2015 Sep; 21(4):1175-81. PubMed ID: 26024742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Clinicopathological significance of LAT1 and ASCT2 in patients with surgically resected esophageal squamous cell carcinoma.
    Honjo H; Kaira K; Miyazaki T; Yokobori T; Kanai Y; Nagamori S; Oyama T; Asao T; Kuwano H
    J Surg Oncol; 2016 Mar; 113(4):381-9. PubMed ID: 26936531
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Leucine stimulates ASCT2 amino acid transporter expression in porcine jejunal epithelial cell line (IPEC-J2) through PI3K/Akt/mTOR and ERK signaling pathways.
    Zhang S; Ren M; Zeng X; He P; Ma X; Qiao S
    Amino Acids; 2014 Dec; 46(12):2633-42. PubMed ID: 25063204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer.
    White MA; Lin C; Rajapakshe K; Dong J; Shi Y; Tsouko E; Mukhopadhyay R; Jasso D; Dawood W; Coarfa C; Frigo DE
    Mol Cancer Res; 2017 Aug; 15(8):1017-1028. PubMed ID: 28507054
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inducible antisense RNA targeting amino acid transporter ATB0/ASCT2 elicits apoptosis in human hepatoma cells.
    Fuchs BC; Perez JC; Suetterlin JE; Chaudhry SB; Bode BP
    Am J Physiol Gastrointest Liver Physiol; 2004 Mar; 286(3):G467-78. PubMed ID: 14563674
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.