363 related articles for article (PubMed ID: 24532803)
1. The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells.
Sahni S; Bae DH; Lane DJ; Kovacevic Z; Kalinowski DS; Jansson PJ; Richardson DR
J Biol Chem; 2014 Apr; 289(14):9692-709. PubMed ID: 24532803
[TBL] [Abstract][Full Text] [Related]
2. The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response.
Merlot AM; Porter GM; Sahni S; Lim EG; Peres P; Richardson DR
Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2094-2110. PubMed ID: 30981813
[TBL] [Abstract][Full Text] [Related]
3. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
Merlot AM; Shafie NH; Yu Y; Richardson V; Jansson PJ; Sahni S; Lane DJR; Kovacevic Z; Kalinowski DS; Richardson DR
Biochem Pharmacol; 2016 Jun; 109():27-47. PubMed ID: 27059255
[TBL] [Abstract][Full Text] [Related]
4. The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).
Chen Z; Zhang D; Yue F; Zheng M; Kovacevic Z; Richardson DR
J Biol Chem; 2012 May; 287(21):17016-17028. PubMed ID: 22453918
[TBL] [Abstract][Full Text] [Related]
5. Iron chelator-induced up-regulation of Ndrg1 inhibits proliferation and EMT process by targeting Wnt/β-catenin pathway in colon cancer cells.
Chen Z; Sun J; Li T; Liu Y; Gao S; Zhi X; Zheng M
Biochem Biophys Res Commun; 2018 Nov; 506(1):114-121. PubMed ID: 30340826
[TBL] [Abstract][Full Text] [Related]
6. The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity.
Gutierrez E; Richardson DR; Jansson PJ
J Biol Chem; 2014 Nov; 289(48):33568-89. PubMed ID: 25301941
[TBL] [Abstract][Full Text] [Related]
7. The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells.
Krishan S; Richardson DR; Sahni S
Biochim Biophys Acta; 2016 Dec; 1863(12):2916-2933. PubMed ID: 27639899
[TBL] [Abstract][Full Text] [Related]
8. Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway.
Sun J; Zhang D; Zheng Y; Zhao Q; Zheng M; Kovacevic Z; Richardson DR
Mol Pharmacol; 2013 Feb; 83(2):454-69. PubMed ID: 23188716
[TBL] [Abstract][Full Text] [Related]
9. NDRG1 suppresses basal and hypoxia-induced autophagy at both the initiation and degradation stages and sensitizes pancreatic cancer cells to lysosomal membrane permeabilization.
Sahni S; Gillson J; Park KC; Chiang S; Leck LYW; Jansson PJ; Richardson DR
Biochim Biophys Acta Gen Subj; 2020 Aug; 1864(8):129625. PubMed ID: 32335136
[TBL] [Abstract][Full Text] [Related]
10. Two mechanisms involving the autophagic and proteasomal pathways process the metastasis suppressor protein, N-myc downstream regulated gene 1.
Sahni S; Park KC; Kovacevic Z; Richardson DR
Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1361-1378. PubMed ID: 30763642
[TBL] [Abstract][Full Text] [Related]
11. The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
Kovacevic Z; Menezes SV; Sahni S; Kalinowski DS; Bae DH; Lane DJ; Richardson DR
J Biol Chem; 2016 Jan; 291(3):1029-52. PubMed ID: 26534963
[TBL] [Abstract][Full Text] [Related]
12. Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding.
Park KC; Geleta B; Leck LYW; Paluncic J; Chiang S; Jansson PJ; Kovacevic Z; Richardson DR
J Biol Chem; 2020 Jan; 295(2):481-503. PubMed ID: 31744884
[TBL] [Abstract][Full Text] [Related]
13. Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.
Fang BA; Kovačević Ž; Park KC; Kalinowski DS; Jansson PJ; Lane DJ; Sahni S; Richardson DR
Biochim Biophys Acta; 2014 Jan; 1845(1):1-19. PubMed ID: 24269900
[TBL] [Abstract][Full Text] [Related]
14. Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer.
Park KC; Paluncic J; Kovacevic Z; Richardson DR
Free Radic Biol Med; 2020 Sep; 157():154-175. PubMed ID: 31132412
[TBL] [Abstract][Full Text] [Related]
15. Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
Wangpu X; Lu J; Xi R; Yue F; Sahni S; Park KC; Menezes S; Huang ML; Zheng M; Kovacevic Z; Richardson DR
Mol Pharmacol; 2016 May; 89(5):521-40. PubMed ID: 26895766
[TBL] [Abstract][Full Text] [Related]
16. Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells.
Dixon KM; Lui GY; Kovacevic Z; Zhang D; Yao M; Chen Z; Dong Q; Assinder SJ; Richardson DR
Br J Cancer; 2013 Feb; 108(2):409-19. PubMed ID: 23287991
[TBL] [Abstract][Full Text] [Related]
17. The Iron Chelator, Dp44mT, Effectively Inhibits Human Oral Squamous Cell Carcinoma Cell Growth in Vitro and in Vivo.
Lee JC; Chiang KC; Feng TH; Chen YJ; Chuang ST; Tsui KH; Chung LC; Juang HH
Int J Mol Sci; 2016 Aug; 17(9):. PubMed ID: 27589737
[TBL] [Abstract][Full Text] [Related]
18. The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways.
Kovacevic Z; Chikhani S; Lui GY; Sivagurunathan S; Richardson DR
Antioxid Redox Signal; 2013 Mar; 18(8):874-87. PubMed ID: 22462691
[TBL] [Abstract][Full Text] [Related]
19. Novel Thiosemicarbazones Inhibit Lysine-Rich Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) Coisolated (LYRIC) and the LYRIC-Induced Epithelial-Mesenchymal Transition via Upregulation of N-Myc Downstream-Regulated Gene 1 (NDRG1).
Xi R; Pun IH; Menezes SV; Fouani L; Kalinowski DS; Huang ML; Zhang X; Richardson DR; Kovacevic Z
Mol Pharmacol; 2017 May; 91(5):499-517. PubMed ID: 28275050
[TBL] [Abstract][Full Text] [Related]
20. Transcriptional regulation of the cyclin-dependent kinase inhibitor, p21
Moussa RS; Kovacevic Z; Bae DH; Lane DJR; Richardson DR
Biochim Biophys Acta Gen Subj; 2018 Mar; 1862(3):761-774. PubMed ID: 29032246
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
