BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 24535564)

  • 1. Mechanisms of amiodarone and valproic acid induced liver steatosis in mouse in vivo act as a template for other hepatotoxicity models.
    Vitins AP; Kienhuis AS; Speksnijder EN; Roodbergen M; Luijten M; van der Ven LT
    Arch Toxicol; 2014 Aug; 88(8):1573-88. PubMed ID: 24535564
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices.
    Szalowska E; van der Burg B; Man HY; Hendriksen PJ; Peijnenburg AA
    PLoS One; 2014; 9(1):e86795. PubMed ID: 24489787
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Subchronic effects of valproic acid on gene expression profiles for lipid metabolism in mouse liver.
    Lee MH; Kim M; Lee BH; Kim JH; Kang KS; Kim HL; Yoon BI; Chung H; Kong G; Lee MO
    Toxicol Appl Pharmacol; 2008 Feb; 226(3):271-84. PubMed ID: 17963808
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A transcriptomics-based hepatotoxicity comparison between the zebrafish embryo and established human and rodent in vitro and in vivo models using cyclosporine A, amiodarone and acetaminophen.
    Driessen M; Vitins AP; Pennings JL; Kienhuis AS; Water Bv; van der Ven LT
    Toxicol Lett; 2015 Jan; 232(2):403-12. PubMed ID: 25448281
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells.
    Rodrigues RM; Branson S; De Boe V; Sachinidis A; Rogiers V; De Kock J; Vanhaecke T
    Arch Toxicol; 2016 Mar; 90(3):677-89. PubMed ID: 25716160
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction.
    van Breda SGJ; Claessen SMH; van Herwijnen M; Theunissen DHJ; Jennen DGJ; de Kok TMCM; Kleinjans JCS
    Toxicology; 2018 Jan; 393():160-170. PubMed ID: 29154799
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gene expression profiles of murine fatty liver induced by the administration of valproic acid.
    Lee MH; Hong I; Kim M; Lee BH; Kim JH; Kang KS; Kim HL; Yoon BI; Chung H; Kong G; Lee MO
    Toxicol Appl Pharmacol; 2007 Apr; 220(1):45-59. PubMed ID: 17292431
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Obeticholic Acid Ameliorates Valproic Acid-Induced Hepatic Steatosis and Oxidative Stress.
    Gai Z; Krajnc E; Samodelov SL; Visentin M; Kullak-Ublick GA
    Mol Pharmacol; 2020 May; 97(5):314-323. PubMed ID: 32098797
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and Consistency with Current Adverse Outcome Pathways.
    López-Pascual E; Rienda I; Perez-Rojas J; Rapisarda A; Garcia-Llorens G; Jover R; Castell JV
    Int J Mol Sci; 2024 May; 25(10):. PubMed ID: 38791241
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ether-phosphatidylcholine characterized by consolidated plasma and liver lipidomics is a predictive biomarker for valproic acid-induced hepatic steatosis.
    Goda K; Saito K; Muta K; Kobayashi A; Saito Y; Sugai S
    J Toxicol Sci; 2018; 43(6):395-405. PubMed ID: 29877216
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Involvement of CYP2E1-ROS-CD36/DGAT2 axis in the pathogenesis of VPA-induced hepatic steatosis in vivo and in vitro.
    Ma L; Wang Y; Chen X; Zhao L; Guo Y
    Toxicology; 2020 Dec; 445():152585. PubMed ID: 33007364
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation.
    McCarthy TC; Pollak PT; Hanniman EA; Sinal CJ
    J Pharmacol Exp Ther; 2004 Dec; 311(3):864-73. PubMed ID: 15265979
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined effects of a high-fat diet and chronic valproic acid treatment on hepatic steatosis and hepatotoxicity in rats.
    Zhang LF; Liu LS; Chu XM; Xie H; Cao LJ; Guo C; A JY; Cao B; Li MJ; Wang GJ; Hao HP
    Acta Pharmacol Sin; 2014 Mar; 35(3):363-72. PubMed ID: 24442146
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The identification of nuclear receptors associated with hepatic steatosis to develop and extend adverse outcome pathways.
    Mellor CL; Steinmetz FP; Cronin MT
    Crit Rev Toxicol; 2016 Feb; 46(2):138-52. PubMed ID: 26451809
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Up-regulation of hepatic fatty acid transporters and inhibition/down-regulation of hepatic OCTN2 contribute to olanzapine-induced liver steatosis.
    Jiang T; Zhang Y; Bai M; Li P; Wang W; Chen M; Ma Z; Zeng S; Zhou H; Jiang H
    Toxicol Lett; 2019 Nov; 316():183-193. PubMed ID: 31437515
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Drug Induced Steatohepatitis: An Uncommon Culprit of a Common Disease.
    Rabinowich L; Shibolet O
    Biomed Res Int; 2015; 2015():168905. PubMed ID: 26273591
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.
    Elphick LM; Pawolleck N; Guschina IA; Chaieb L; Eikel D; Nau H; Harwood JL; Plant NJ; Williams RS
    Dis Model Mech; 2012 Mar; 5(2):231-40. PubMed ID: 22003123
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of the Potential Risk of Drugs to Induce Hepatotoxicity in Human-Relationships between Hepatic Steatosis Observed in Non-Clinical Toxicity Study and Hepatotoxicity in Humans.
    Goda K; Kobayashi A; Takahashi A; Takahashi T; Saito K; Maekawa K; Saito Y; Sugai S
    Int J Mol Sci; 2017 Apr; 18(4):. PubMed ID: 28417920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Study of Valproic Acid-Enhanced Hepatocyte Steatosis.
    Chang R; Chou MC; Hung LY; Wang ME; Hsu MC; Chiu CH
    Biomed Res Int; 2016; 2016():9576503. PubMed ID: 27034954
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells.
    Anthérieu S; Rogue A; Fromenty B; Guillouzo A; Robin MA
    Hepatology; 2011 Jun; 53(6):1895-905. PubMed ID: 21391224
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.