BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 24549370)

  • 1. Inactivation of von Hippel-Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR-210/VMP1 signaling pathway.
    Liu T; Zhao L; Chen W; Li Z; Hou H; Ding L; Li X
    Int J Mol Med; 2014 May; 33(5):1236-42. PubMed ID: 24549370
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MIR-92 stimulates VEGF by inhibiting von Hippel-Lindau gene product in epithelial ovarian cancer.
    Guo FJ; Shao YP; Wang YP; Jin YM; Liu SS; Wang QY
    J Biol Regul Homeost Agents; 2017 Jul-Sep,; 31(3):615-624. PubMed ID: 28952293
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R; Horiuchi A; Kikuchi N; Yoshida J; Hayashi A; Ota M; Katsuyama Y; Melillo G; Konishi I
    Hum Pathol; 2007 Sep; 38(9):1310-20. PubMed ID: 17555795
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate.
    Merlo A; Bernardo-Castiñeira C; Sáenz-de-Santa-María I; Pitiot AS; Balbín M; Astudillo A; Valdés N; Scola B; Del Toro R; Méndez-Ferrer S; Piruat JI; Suarez C; Chiara MD
    Oncotarget; 2017 Jan; 8(4):6700-6717. PubMed ID: 28036268
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of somatic VHL gene mutations in sporadic head and neck paragangliomas in association with activation of the HIF-1α/miR-210 signaling pathway.
    Merlo A; de Quirós SB; de Santa-María IS; Pitiot AS; Balbín M; Astudillo A; Scola B; Arístegui M; Quer M; Suarez C; Chiara MD
    J Clin Endocrinol Metab; 2013 Oct; 98(10):E1661-6. PubMed ID: 23902947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition.
    Liu N; Xia WY; Liu SS; Chen HY; Sun L; Liu MY; Li LF; Lu HM; Fu YJ; Wang P; Wu H; Gao JX
    Sci Rep; 2016 Feb; 6():20489. PubMed ID: 26841847
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma.
    Lee S; Garner EI; Welch WR; Berkowitz RS; Mok SC
    Gynecol Oncol; 2007 Aug; 106(2):311-7. PubMed ID: 17532031
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
    Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TGFBI-promoted adhesion, migration and invasion of human renal cell carcinoma depends on inactivation of von Hippel-Lindau tumor suppressor.
    Shang D; Liu Y; Yang P; Chen Y; Tian Y
    Urology; 2012 Apr; 79(4):966.e1-7. PubMed ID: 22341602
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of fibronectin and HIF-1alpha in renal cell carcinomas: relationship to von Hippel-Lindau gene inactivation.
    He Z; Liu S; Guo M; Mao J; Hughson MD
    Cancer Genet Cytogenet; 2004 Jul; 152(2):89-94. PubMed ID: 15262424
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypoxia Inducible Factor-1α Inhibition in Von Hippel Lindau-mutant Malignant Pleural Mesothelioma Cells.
    Shukuya T; Oyanagi J; Serizawa M; Watanabe M; Yamamoto N; Koh Y
    Anticancer Res; 2020 Apr; 40(4):1867-1874. PubMed ID: 32234874
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NF-kappaB-dependent plasticity of the epithelial to mesenchymal transition induced by Von Hippel-Lindau inactivation in renal cell carcinomas.
    Pantuck AJ; An J; Liu H; Rettig MB
    Cancer Res; 2010 Jan; 70(2):752-61. PubMed ID: 20068166
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of VHL and HIF-1α and Their Clinicopathologic Significance in Benign and Malignant Lesions of the Gallbladder.
    Yang Z; Yang Z; Xiong L; Huang S; Liu J; Yang L; Miao X
    Appl Immunohistochem Mol Morphol; 2011 Dec; 19(6):534-9. PubMed ID: 21415706
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA; Ashcroft M
    Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element.
    Xu J; Wang B; Xu Y; Sun L; Tian W; Shukla D; Barod R; Grillari J; Grillari-Voglauer R; Maxwell PH; Esteban MA
    Oncogene; 2012 Feb; 31(8):1065-72. PubMed ID: 21841824
    [TBL] [Abstract][Full Text] [Related]  

  • 16. hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer.
    Camps C; Buffa FM; Colella S; Moore J; Sotiriou C; Sheldon H; Harris AL; Gleadle JM; Ragoussis J
    Clin Cancer Res; 2008 Mar; 14(5):1340-8. PubMed ID: 18316553
    [TBL] [Abstract][Full Text] [Related]  

  • 17. VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling.
    Chen L; Han L; Zhang K; Shi Z; Zhang J; Zhang A; Wang Y; Song Y; Li Y; Jiang T; Pu P; Jiang C; Kang C
    Neuro Oncol; 2012 Aug; 14(8):1026-36. PubMed ID: 22649212
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MicroRNA-135b-5p promotes endothelial cell proliferation and angiogenesis in diabetic retinopathy mice by inhibiting Von Hipp-el-Lindau and elevating hypoxia inducible factor α expression.
    Liu L; Xu H; Zhao H; Sui D
    J Drug Target; 2021 Mar; 29(3):300-309. PubMed ID: 33032456
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Down-regulation of HIF-1alpha by oncolytic reovirus infection independently of VHL and p53.
    Cho IR; Koh SS; Min HJ; Park EH; Ratakorn S; Jhun BH; Jeong SH; Yoo YH; Youn HD; Johnston RN; Chung YH
    Cancer Gene Ther; 2010 May; 17(5):365-72. PubMed ID: 20075985
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation of the von Hippel-Lindau protein (VHL) by protein kinase CK2 reduces its protein stability and affects p53 and HIF-1alpha mediated transcription.
    Ampofo E; Kietzmann T; Zimmer A; Jakupovic M; Montenarh M; Götz C
    Int J Biochem Cell Biol; 2010 Oct; 42(10):1729-35. PubMed ID: 20637892
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.