BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 24550394)

  • 1. Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-β (TGF-β) signaling promoting SMAD3 activation and fibrosis via Gremlin protein.
    O'Reilly S; Ciechomska M; Cant R; van Laar JM
    J Biol Chem; 2014 Apr; 289(14):9952-60. PubMed ID: 24550394
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Parathyroid Hormone-Related Protein Interacts With the Transforming Growth Factor-β/Bone Morphogenetic Protein-2/Gremlin Signaling Pathway to Regulate Proinflammatory and Profibrotic Mediators in Pancreatic Acinar and Stellate Cells.
    Bhatia V; Cao Y; Ko TC; Falzon M
    Pancreas; 2016; 45(5):659-70. PubMed ID: 26495794
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling.
    Epstein Shochet G; Brook E; Bardenstein-Wald B; Shitrit D
    Respir Res; 2020 Feb; 21(1):56. PubMed ID: 32070329
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gremlin is a downstream profibrotic mediator of transforming growth factor-beta in cultured renal cells.
    Rodrigues-Diez R; Lavoz C; Carvajal G; Rayego-Mateos S; Rodrigues Diez RR; Ortiz A; Egido J; Mezzano S; Ruiz-Ortega M
    Nephron Exp Nephrol; 2012; 122(1-2):62-74. PubMed ID: 23548835
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A high-fat diet rich in corn oil induces cardiac fibrosis in rats by activating JAK2/STAT3 and subsequent activation of ANG II/TGF-1β/Smad3 pathway: The role of ROS and IL-6 trans-signaling.
    Eid RA; Alkhateeb MA; El-Kott AF; Eleawa SM; Zaki MSA; Alaboodi SA; Salem Al-Shudiefat AA; Aldera H; Alnamar NM; Alassiri M; Khalil MA
    J Food Biochem; 2019 Aug; 43(8):e12952. PubMed ID: 31368573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma.
    Lakos G; Takagawa S; Chen SJ; Ferreira AM; Han G; Masuda K; Wang XJ; DiPietro LA; Varga J
    Am J Pathol; 2004 Jul; 165(1):203-17. PubMed ID: 15215176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TGF-β2 induces transdifferentiation and fibrosis in human lens epithelial cells via regulating gremlin and CTGF.
    Ma B; Kang Q; Qin L; Cui L; Pei C
    Biochem Biophys Res Commun; 2014 May; 447(4):689-95. PubMed ID: 24755068
    [TBL] [Abstract][Full Text] [Related]  

  • 8. EphrinB2 Regulates Cardiac Fibrosis Through Modulating the Interaction of Stat3 and TGF-β/Smad3 Signaling.
    Su SA; Yang D; Wu Y; Xie Y; Zhu W; Cai Z; Shen J; Fu Z; Wang Y; Jia L; Wang Y; Wang JA; Xiang M
    Circ Res; 2017 Sep; 121(6):617-627. PubMed ID: 28743805
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways.
    Pannu J; Nakerakanti S; Smith E; ten Dijke P; Trojanowska M
    J Biol Chem; 2007 Apr; 282(14):10405-13. PubMed ID: 17317656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Qishen granule attenuates cardiac fibrosis by regulating TGF-β /Smad3 and GSK-3β pathway.
    Zeng Z; Wang Q; Yang X; Ren Y; Jiao S; Zhu Q; Guo D; Xia K; Wang Y; Li C; Wang W
    Phytomedicine; 2019 Sep; 62():152949. PubMed ID: 31102891
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Full-length IL-33 regulates Smad3 phosphorylation and gene transcription in a distinctive AP2-dependent manner.
    Luzina IG; Fishelevich R; Hampton BS; Courneya JP; Parisella FR; Lugkey KN; Baleno FX; Choi D; Kopach P; Lockatell V; Todd NW; Atamas SP
    Cell Immunol; 2020 Nov; 357():104203. PubMed ID: 32977155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bone morphogenetic protein 4 inhibits TGF-beta2 stimulation of extracellular matrix proteins in optic nerve head cells: role of gremlin in ECM modulation.
    Zode GS; Clark AF; Wordinger RJ
    Glia; 2009 May; 57(7):755-66. PubMed ID: 19031438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. JAK/STAT3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells.
    Liu RY; Zeng Y; Lei Z; Wang L; Yang H; Liu Z; Zhao J; Zhang HT
    Int J Oncol; 2014 May; 44(5):1643-51. PubMed ID: 24573038
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gremlin aggravates hyperglycemia-induced podocyte injury by a TGFβ/smad dependent signaling pathway.
    Li G; Li Y; Liu S; Shi Y; Chi Y; Liu G; Shan T
    J Cell Biochem; 2013 Sep; 114(9):2101-13. PubMed ID: 23553804
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prevention of early postnatal hyperalimentation protects against activation of transforming growth factor-β/bone morphogenetic protein and interleukin-6 signaling in rat lungs after intrauterine growth restriction.
    Alcázar MA; Dinger K; Rother E; Östreicher I; Vohlen C; Plank C; Dötsch J
    J Nutr; 2014 Dec; 144(12):1943-51. PubMed ID: 25411031
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Natural flavonol fisetin attenuated hyperuricemic nephropathy via inhibiting IL-6/JAK2/STAT3 and TGF-β/SMAD3 signaling.
    Ren Q; Tao S; Guo F; Wang B; Yang L; Ma L; Fu P
    Phytomedicine; 2021 Jul; 87():153552. PubMed ID: 33994251
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transforming growth factor-β (TGF-β)-mediated connective tissue growth factor (CTGF) expression in hepatic stellate cells requires Stat3 signaling activation.
    Liu Y; Liu H; Meyer C; Li J; Nadalin S; Königsrainer A; Weng H; Dooley S; Ten Dijke P
    J Biol Chem; 2013 Oct; 288(42):30708-30719. PubMed ID: 24005672
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gremlin-mediated decrease in bone morphogenetic protein signaling promotes pulmonary fibrosis.
    Myllärniemi M; Lindholm P; Ryynänen MJ; Kliment CR; Salmenkivi K; Keski-Oja J; Kinnula VL; Oury TD; Koli K
    Am J Respir Crit Care Med; 2008 Feb; 177(3):321-9. PubMed ID: 17975199
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gankyrin promotes epithelial-mesenchymal transition and metastasis in NSCLC through forming a closed circle with IL-6/ STAT3 and TGF-β/SMAD3 signaling pathway.
    Wang WP; Sun Y; Lu Q; Zhao JB; Wang XJ; Chen Z; Ni YF; Wang JZ; Han Y; Zhang ZP; Yan XL; Li XF
    Oncotarget; 2017 Jan; 8(4):5909-5923. PubMed ID: 27992365
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury.
    Kurundkar AR; Kurundkar D; Rangarajan S; Locy ML; Zhou Y; Liu RM; Zmijewski J; Thannickal VJ
    FASEB J; 2016 Jun; 30(6):2135-50. PubMed ID: 26884454
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.