271 related articles for article (PubMed ID: 24552538)
1. Human NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated inactivation of reactive quinoneimine metabolites of diclofenac and mefenamic acid.
Vredenburg G; Elias NS; Venkataraman H; Hendriks DF; Vermeulen NP; Commandeur JN; Vos JC
Chem Res Toxicol; 2014 Apr; 27(4):576-86. PubMed ID: 24552538
[TBL] [Abstract][Full Text] [Related]
2. Cytochrome P450-mediated bioactivation of mefenamic acid to quinoneimine intermediates and inactivation by human glutathione S-transferases.
Venkataraman H; den Braver MW; Vermeulen NP; Commandeur JN
Chem Res Toxicol; 2014 Dec; 27(12):2071-81. PubMed ID: 25372302
[TBL] [Abstract][Full Text] [Related]
3. Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations.
den Braver-Sewradj SP; den Braver MW; Toorneman RM; van Leeuwen S; Zhang Y; Dekker SJ; Vermeulen NPE; Commandeur JNM; Vos JC
Chem Res Toxicol; 2018 Feb; 31(2):116-126. PubMed ID: 29281794
[TBL] [Abstract][Full Text] [Related]
4. Human superoxide dismutase 1 attenuates quinoneimine metabolite formation from mefenamic acid.
Ogiso T; Fukami T; Zhongzhe C; Konishi K; Nakano M; Nakajima M
Toxicology; 2021 Jan; 448():152648. PubMed ID: 33259822
[TBL] [Abstract][Full Text] [Related]
5. Effect of human glutathione S-transferases on glutathione-dependent inactivation of cytochrome P450-dependent reactive intermediates of diclofenac.
Dragovic S; Boerma JS; Vermeulen NP; Commandeur JN
Chem Res Toxicol; 2013 Nov; 26(11):1632-41. PubMed ID: 24083800
[TBL] [Abstract][Full Text] [Related]
6. Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: Possible implications for susceptibility to amodiaquine-induced liver toxicity.
Zhang Y; den Braver-Sewradj SP; Vos JC; Vermeulen NPE; Commandeur JNM
Toxicol Lett; 2017 Jun; 275():83-91. PubMed ID: 28478157
[TBL] [Abstract][Full Text] [Related]
7. Effect of human glutathione S-transferase hGSTP1-1 polymorphism on the detoxification of reactive metabolites of clozapine, diclofenac and acetaminophen.
Dragovic S; Venkataraman H; Begheijn S; Vermeulen NP; Commandeur JN
Toxicol Lett; 2014 Jan; 224(2):272-81. PubMed ID: 24185126
[TBL] [Abstract][Full Text] [Related]
8. Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen.
Moffit JS; Aleksunes LM; Kardas MJ; Slitt AL; Klaassen CD; Manautou JE
Toxicology; 2007 Feb; 230(2-3):197-206. PubMed ID: 17188792
[TBL] [Abstract][Full Text] [Related]
9. One-electron oxidation of diclofenac by human cytochrome P450s as a potential bioactivation mechanism for formation of 2'-(glutathion-S-yl)-deschloro-diclofenac.
Boerma JS; Vermeulen NP; Commandeur JN
Chem Biol Interact; 2014 Jan; 207():32-40. PubMed ID: 24246759
[TBL] [Abstract][Full Text] [Related]
10. Simulation of interindividual differences in inactivation of reactive para-benzoquinone imine metabolites of diclofenac by glutathione S-transferases in human liver cytosol.
den Braver MW; Zhang Y; Venkataraman H; Vermeulen NP; Commandeur JN
Toxicol Lett; 2016 Jul; 255():52-62. PubMed ID: 27183920
[TBL] [Abstract][Full Text] [Related]
11. Indigofera suffruticosa Mill extracts up-regulate the expression of the π class of glutathione S-transferase and NAD(P)H: quinone oxidoreductase 1 in rat Clone 9 liver cells.
Chen CC; Liu CS; Li CC; Tsai CW; Yao HT; Liu TC; Chen HW; Chen PY; Wu YL; Lii CK; Liu KL
Food Chem Toxicol; 2013 Sep; 59():610-7. PubMed ID: 23831193
[TBL] [Abstract][Full Text] [Related]
12. Mass spectrometric characterization of protein adducts of multiple P450-dependent reactive intermediates of diclofenac to human glutathione-S-transferase P1-1.
Boerma JS; Dragovic S; Vermeulen NP; Commandeur JN
Chem Res Toxicol; 2012 Nov; 25(11):2532-41. PubMed ID: 22998212
[TBL] [Abstract][Full Text] [Related]
13. Problematic detoxification of estrogen quinones by NAD(P)H-dependent quinone oxidoreductase and glutathione-S-transferase.
Chandrasena RE; Edirisinghe PD; Bolton JL; Thatcher GR
Chem Res Toxicol; 2008 Jul; 21(7):1324-9. PubMed ID: 18588320
[TBL] [Abstract][Full Text] [Related]
14. Role of human glutathione S-transferases in the inactivation of reactive metabolites of clozapine.
Dragovic S; Boerma JS; van Bergen L; Vermeulen NP; Commandeur JN
Chem Res Toxicol; 2010 Sep; 23(9):1467-76. PubMed ID: 20849150
[TBL] [Abstract][Full Text] [Related]
15. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
Zhao SX; Dalvie DK; Kelly JM; Soglia JR; Frederick KS; Smith EB; Obach RS; Kalgutkar AS
Chem Res Toxicol; 2007 Nov; 20(11):1649-57. PubMed ID: 17907785
[TBL] [Abstract][Full Text] [Related]
16. Identification of quinone imine containing glutathione conjugates of diclofenac in rat bile.
Waldon DJ; Teffera Y; Colletti AE; Liu J; Zurcher D; Copeland KW; Zhao Z
Chem Res Toxicol; 2010 Dec; 23(12):1947-53. PubMed ID: 21053927
[TBL] [Abstract][Full Text] [Related]
17. Characterization of cytochrome P450 isoforms involved in sequential two-step bioactivation of diclofenac to reactive p-benzoquinone imines.
den Braver MW; den Braver-Sewradj SP; Vermeulen NP; Commandeur JN
Toxicol Lett; 2016 Jun; 253():46-54. PubMed ID: 27130197
[TBL] [Abstract][Full Text] [Related]
18. Evidence from ESI-MS for NQO1-catalyzed reduction of estrogen ortho-quinones.
Gaikwad NW; Rogan EG; Cavalieri EL
Free Radic Biol Med; 2007 Nov; 43(9):1289-98. PubMed ID: 17893042
[TBL] [Abstract][Full Text] [Related]
19. Metabolic activation of mefenamic acid leading to mefenamyl-S-acyl-glutathione adduct formation in vitro and in vivo in rat.
Grillo MP; Tadano Lohr M; Wait JC
Drug Metab Dispos; 2012 Aug; 40(8):1515-26. PubMed ID: 22577085
[TBL] [Abstract][Full Text] [Related]
20. Benzimidazole- and benzothiazole-quinones: excellent substrates for NAD(P)H:quinone oxidoreductase 1.
Newsome JJ; Colucci MA; Hassani M; Beall HD; Moody CJ
Org Biomol Chem; 2007 Nov; 5(22):3665-73. PubMed ID: 17971996
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
