BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 24558194)

  • 1. HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells.
    Fujita N; Hirose Y; Tran CM; Chiba K; Miyamoto T; Toyama Y; Shapiro IM; Risbud MV
    FASEB J; 2014 Jun; 28(6):2455-65. PubMed ID: 24558194
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
    Li J; Yuan W; Jiang S; Ye W; Yang H; Shapiro IM; Risbud MV
    J Biol Chem; 2015 Mar; 290(11):7195-207. PubMed ID: 25635047
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia.
    Fujita N; Markova D; Anderson DG; Chiba K; Toyama Y; Shapiro IM; Risbud MV
    J Biol Chem; 2012 May; 287(20):16975-86. PubMed ID: 22451659
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc.
    Wang J; Markova D; Anderson DG; Zheng Z; Shapiro IM; Risbud MV
    J Biol Chem; 2011 Nov; 286(46):39738-49. PubMed ID: 21949132
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lentivirus-shRNA Mediated Prolyl Hydroxylase 2 Knockdown Increases HIF-1α and Inhibits Nucleus Pulposus Cells Degeneration.
    Chen Q; Shi F; Yang C; Mao G; Zhou C; Liu L; Yang X; Song Y
    Cells Tissues Organs; 2023; 212(2):185-193. PubMed ID: 34781297
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.
    Schoepflin ZR; Shapiro IM; Risbud MV
    J Bone Miner Res; 2016 Jun; 31(6):1287-99. PubMed ID: 26765925
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling.
    Fujita N; Gogate SS; Chiba K; Toyama Y; Shapiro IM; Risbud MV
    J Biol Chem; 2012 Nov; 287(47):39942-53. PubMed ID: 22948157
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1α signaling in nucleus pulposus cells.
    Pan H; Strickland A; Madhu V; Johnson ZI; Chand SN; Brody JR; Fertala A; Zheng Z; Shapiro IM; Risbud MV
    Matrix Biol; 2019 Apr; 77():23-40. PubMed ID: 30092282
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: possible implications in controlling dystrophic mineralization in the intervertebral disc.
    Skubutyte R; Markova D; Freeman TA; Anderson DG; Dion AS; Williams CJ; Shapiro IM; Risbud MV
    Arthritis Rheum; 2010 Sep; 62(9):2707-15. PubMed ID: 20496369
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity.
    Tran CM; Fujita N; Huang BL; Ong JR; Lyons KM; Shapiro IM; Risbud MV
    J Biol Chem; 2013 May; 288(18):12654-66. PubMed ID: 23530034
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteins.
    Gogate SS; Nasser R; Shapiro IM; Risbud MV
    Arthritis Rheum; 2011 Jul; 63(7):1950-60. PubMed ID: 21400481
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PHD/HIF-1 upregulates CA12 to protect against degenerative disc disease: a human sample, in vitro and ex vivo study.
    Chen S; Fang XQ; Wang Q; Wang SW; Hu ZJ; Zhou ZJ; Xu WB; Wang JY; Qin A; Fan SW
    Lab Invest; 2016 May; 96(5):561-9. PubMed ID: 26901836
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: role of Hsp70 in HIF-1α degradation.
    Gogate SS; Fujita N; Skubutyte R; Shapiro IM; Risbud MV
    J Bone Miner Res; 2012 May; 27(5):1106-17. PubMed ID: 22322648
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc.
    Fujita N; Chiba K; Shapiro IM; Risbud MV
    J Bone Miner Res; 2012 Feb; 27(2):401-12. PubMed ID: 21987385
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SIRT1 expression is refractory to hypoxia and inflammatory cytokines in nucleus pulposus cells: Novel regulation by HIF-1α and NF-κB signaling.
    Wang X; Li H; Xu K; Zhu H; Peng Y; Liang A; Li C; Huang D; Ye W
    Cell Biol Int; 2016 Jun; 40(6):716-26. PubMed ID: 27061137
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of Hypoxia-Inducible Factor-1α Signaling Pathway Has the Protective Effect of Intervertebral Disc Degeneration.
    Kim JW; An HJ; Yeo H; Jeong Y; Lee H; Lee J; Nam K; Lee J; Shin DE; Lee S
    Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768786
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc.
    Agrawal A; Gajghate S; Smith H; Anderson DG; Albert TJ; Shapiro IM; Risbud MV
    Arthritis Rheum; 2008 Dec; 58(12):3798-808. PubMed ID: 19035510
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Effect of "nape seven needles" on expression of hypoxia inducible factor-1α and Notch1 in cervical intervertebral disc degeneration rats].
    Ding FF; Lu Y
    Zhen Ci Yan Jiu; 2022 Oct; 47(10):872-7. PubMed ID: 36301163
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.
    Risbud MV; Guttapalli A; Stokes DG; Hawkins D; Danielson KG; Schaer TP; Albert TJ; Shapiro IM
    J Cell Biochem; 2006 May; 98(1):152-9. PubMed ID: 16408279
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk.
    Agrawal A; Guttapalli A; Narayan S; Albert TJ; Shapiro IM; Risbud MV
    Am J Physiol Cell Physiol; 2007 Aug; 293(2):C621-31. PubMed ID: 17442734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.