BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 24558502)

  • 1. Fibrous papule of the face, similar to tuberous sclerosis complex-associated angiofibroma, shows activation of the mammalian target of rapamycin pathway: evidence for a novel therapeutic strategy?
    Chan JY; Wang KH; Fang CL; Chen WY
    PLoS One; 2014; 9(2):e89467. PubMed ID: 24558502
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mesenchymal-epithelial interactions involving epiregulin in tuberous sclerosis complex hamartomas.
    Li S; Takeuchi F; Wang JA; Fan Q; Komurasaki T; Billings EM; Pacheco-Rodriguez G; Moss J; Darling TN
    Proc Natl Acad Sci U S A; 2008 Mar; 105(9):3539-44. PubMed ID: 18292222
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation.
    Chan JA; Zhang H; Roberts PS; Jozwiak S; Wieslawa G; Lewin-Kowalik J; Kotulska K; Kwiatkowski DJ
    J Neuropathol Exp Neurol; 2004 Dec; 63(12):1236-42. PubMed ID: 15624760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of expression of tuberin and hamartin in tuberous sclerosis complex-associated but not in sporadic angiofibromas.
    Fackler I; DeClue JE; Rust H; Vu PA; Kutzner H; Rütten A; Kaddu S; Sander CA; Volkenandt M; Johnson MW; Vinters HV; Wienecke R
    J Cutan Pathol; 2003 Mar; 30(3):174-7. PubMed ID: 12641776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biallelic TSC gene inactivation in tuberous sclerosis complex.
    Crino PB; Aronica E; Baltuch G; Nathanson KL
    Neurology; 2010 May; 74(21):1716-23. PubMed ID: 20498439
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Bama miniature pig model of monoallelic TSC1 mutation for human tuberous sclerosis complex.
    Li X; Hu T; Liu J; Fang B; Geng X; Xiong Q; Zhang L; Jin Y; Liu X; Li L; Wang Y; Li R; Bai X; Yang H; Dai Y
    J Genet Genomics; 2020 Dec; 47(12):735-742. PubMed ID: 33612456
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sun exposure causes somatic second-hit mutations and angiofibroma development in tuberous sclerosis complex.
    Tyburczy ME; Wang JA; Li S; Thangapazham R; Chekaluk Y; Moss J; Kwiatkowski DJ; Darling TN
    Hum Mol Genet; 2014 Apr; 23(8):2023-9. PubMed ID: 24271014
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.
    Tee AR; Fingar DC; Manning BD; Kwiatkowski DJ; Cantley LC; Blenis J
    Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13571-6. PubMed ID: 12271141
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors.
    Kenerson HL; Aicher LD; True LD; Yeung RS
    Cancer Res; 2002 Oct; 62(20):5645-50. PubMed ID: 12384518
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner.
    Di Nardo A; Kramvis I; Cho N; Sadowski A; Meikle L; Kwiatkowski DJ; Sahin M
    J Neurosci; 2009 May; 29(18):5926-37. PubMed ID: 19420259
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditions.
    Matthew EM; Hart LS; Astrinidis A; Navaraj A; Dolloff NG; Dicker DT; Henske EP; El-Deiry WS
    Cell Cycle; 2009 Dec; 8(24):4168-75. PubMed ID: 20054236
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis.
    Li S; Thangapazham RL; Wang JA; Rajesh S; Kao TC; Sperling L; Moss J; Darling TN
    Nat Commun; 2011; 2():235. PubMed ID: 21407201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.
    Roux PP; Ballif BA; Anjum R; Gygi SP; Blenis J
    Proc Natl Acad Sci U S A; 2004 Sep; 101(37):13489-94. PubMed ID: 15342917
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dysregulation of autophagy in melanocytes contributes to hypopigmented macules in tuberous sclerosis complex.
    Yang F; Yang L; Wataya-Kaneda M; Hasegawa J; Yoshimori T; Tanemura A; Tsuruta D; Katayama I
    J Dermatol Sci; 2018 Feb; 89(2):155-164. PubMed ID: 29146131
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rhebbing up mTOR: new insights on TSC1 and TSC2, and the pathogenesis of tuberous sclerosis.
    Kwiatkowski DJ
    Cancer Biol Ther; 2003; 2(5):471-6. PubMed ID: 14614311
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fetal brain lesions in tuberous sclerosis complex: TORC1 activation and inflammation.
    Prabowo AS; Anink JJ; Lammens M; Nellist M; van den Ouweland AM; Adle-Biassette H; Sarnat HB; Flores-Sarnat L; Crino PB; Aronica E
    Brain Pathol; 2013 Jan; 23(1):45-59. PubMed ID: 22805177
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pathogenesis of multifocal micronodular pneumocyte hyperplasia and lymphangioleiomyomatosis in tuberous sclerosis and association with tuberous sclerosis genes TSC1 and TSC2.
    Maruyama H; Ohbayashi C; Hino O; Tsutsumi M; Konishi Y
    Pathol Int; 2001 Aug; 51(8):585-94. PubMed ID: 11564212
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tuberous Sclerosis Complex in 29 Children: Clinical and Genetic Analysis and Facial Angiofibroma Responses to Topical Sirolimus.
    Wang S; Liu Y; Wei J; Zhang J; Wang Z; Xu Z
    Pediatr Dermatol; 2017 Sep; 34(5):572-577. PubMed ID: 28771801
    [TBL] [Abstract][Full Text] [Related]  

  • 19. mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development.
    Peng H; Liu J; Sun Q; Chen R; Wang Y; Duan J; Li C; Li B; Jing Y; Chen X; Mao Q; Xu KF; Walker CL; Li J; Wang J; Zhang H
    Oncogene; 2013 Sep; 32(39):4702-11. PubMed ID: 23108404
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes.
    Miyazaki M; McCarthy JJ; Esser KA
    FEBS J; 2010 May; 277(9):2180-91. PubMed ID: 20412061
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.