These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

429 related articles for article (PubMed ID: 24563541)

  • 41. Smac mimetics can provoke lytic cell death that is neither apoptotic nor necroptotic.
    Miles MA; Caruso S; Baxter AA; Poon IKH; Hawkins CJ
    Apoptosis; 2020 Aug; 25(7-8):500-518. PubMed ID: 32440848
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression.
    Petersen SL; Peyton M; Minna JD; Wang X
    Proc Natl Acad Sci U S A; 2010 Jun; 107(26):11936-41. PubMed ID: 20547836
    [TBL] [Abstract][Full Text] [Related]  

  • 43. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.
    Vince JE; Wong WW; Khan N; Feltham R; Chau D; Ahmed AU; Benetatos CA; Chunduru SK; Condon SM; McKinlay M; Brink R; Leverkus M; Tergaonkar V; Schneider P; Callus BA; Koentgen F; Vaux DL; Silke J
    Cell; 2007 Nov; 131(4):682-93. PubMed ID: 18022363
    [TBL] [Abstract][Full Text] [Related]  

  • 44. TNF-alpha induces two distinct caspase-8 activation pathways.
    Wang L; Du F; Wang X
    Cell; 2008 May; 133(4):693-703. PubMed ID: 18485876
    [TBL] [Abstract][Full Text] [Related]  

  • 45. A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma.
    Amaravadi RK; Schilder RJ; Martin LP; Levin M; Graham MA; Weng DE; Adjei AA
    Mol Cancer Ther; 2015 Nov; 14(11):2569-75. PubMed ID: 26333381
    [TBL] [Abstract][Full Text] [Related]  

  • 46. USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.
    Lee EW; Seong D; Seo J; Jeong M; Lee HK; Song J
    Cell Death Differ; 2015 Sep; 22(9):1463-76. PubMed ID: 25613375
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Simulating and predicting cellular and in vivo responses of colon cancer to combined treatment with chemotherapy and IAP antagonist Birinapant/TL32711.
    Crawford N; Salvucci M; Hellwig CT; Lincoln FA; Mooney RE; O'Connor CL; Prehn JH; Longley DB; Rehm M
    Cell Death Differ; 2018 Nov; 25(11):1952-1966. PubMed ID: 29500433
    [TBL] [Abstract][Full Text] [Related]  

  • 48. CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex.
    Maas C; Tromp JM; van Laar J; Thijssen R; Elias JA; Malara A; Krippner-Heidenreich A; Silke J; van Oers MH; Eldering E
    Cell Death Dis; 2013 Aug; 4(8):e782. PubMed ID: 23990022
    [TBL] [Abstract][Full Text] [Related]  

  • 49. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO).
    Ng CP; Bonavida B
    Mol Cancer Ther; 2002 Oct; 1(12):1051-8. PubMed ID: 12481428
    [TBL] [Abstract][Full Text] [Related]  

  • 50. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.
    Vince JE; Chau D; Callus B; Wong WW; Hawkins CJ; Schneider P; McKinlay M; Benetatos CA; Condon SM; Chunduru SK; Yeoh G; Brink R; Vaux DL; Silke J
    J Cell Biol; 2008 Jul; 182(1):171-84. PubMed ID: 18606850
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Effects of Birinapant on Proliferation and Invasion of MGC-803 Gastric Cancer Cells and Mechanism Underlying These Effects.
    Zhu DL; Shuai LY
    Bull Exp Biol Med; 2021 May; 171(1):56-61. PubMed ID: 34050412
    [TBL] [Abstract][Full Text] [Related]  

  • 52. LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC.
    Yang C; Wang H; Zhang B; Chen Y; Zhang Y; Sun X; Xiao G; Nan K; Ren H; Qin S
    J Exp Clin Cancer Res; 2016 Sep; 35(1):158. PubMed ID: 27737687
    [TBL] [Abstract][Full Text] [Related]  

  • 53. A novel Smac mimetic APG-1387 demonstrates potent antitumor activity in nasopharyngeal carcinoma cells by inducing apoptosis.
    Li N; Feng L; Han HQ; Yuan J; Qi XK; Lian YF; Kuang BH; Zhang YC; Deng CC; Zhang HJ; Yao YY; Xu M; He GP; Zhao BC; Gao L; Feng QS; Chen LZ; Yang L; Yang D; Zeng YX
    Cancer Lett; 2016 Oct; 381(1):14-22. PubMed ID: 27424523
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL.
    McComb S; Aguadé-Gorgorió J; Harder L; Marovca B; Cario G; Eckert C; Schrappe M; Stanulla M; von Stackelberg A; Bourquin JP; Bornhauser BC
    Sci Transl Med; 2016 May; 8(339):339ra70. PubMed ID: 27194728
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.
    Feltham R; Moulin M; Vince JE; Mace PD; Wong WW; Anderton H; Day CL; Vaux DL; Silke J
    J Biol Chem; 2010 Jun; 285(23):17525-36. PubMed ID: 20356846
    [TBL] [Abstract][Full Text] [Related]  

  • 56. NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2.
    Diessenbacher P; Hupe M; Sprick MR; Kerstan A; Geserick P; Haas TL; Wachter T; Neumann M; Walczak H; Silke J; Leverkus M
    J Invest Dermatol; 2008 May; 128(5):1134-47. PubMed ID: 17989734
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Lobaplatin induces pyroptosis through regulating cIAP1/2, Ripoptosome and ROS in nasopharyngeal carcinoma.
    Chen Z; Xu G; Wu D; Wu S; Gong L; Li Z; Luo G; Hu J; Chen J; Huang X; Chen C; Jiang Z; Li X
    Biochem Pharmacol; 2020 Jul; 177():114023. PubMed ID: 32413426
    [TBL] [Abstract][Full Text] [Related]  

  • 58. ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth.
    Ward GA; Lewis EJ; Ahn JS; Johnson CN; Lyons JF; Martins V; Munck JM; Rich SJ; Smyth T; Thompson NT; Williams PA; Wilsher NE; Wallis NG; Chessari G
    Mol Cancer Ther; 2018 Jul; 17(7):1381-1391. PubMed ID: 29695633
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment.
    Lu J; McEachern D; Sun H; Bai L; Peng Y; Qiu S; Miller R; Liao J; Yi H; Liu M; Bellail A; Hao C; Sun SY; Ting AT; Wang S
    Mol Cancer Ther; 2011 May; 10(5):902-14. PubMed ID: 21372226
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).
    Flygare JA; Beresini M; Budha N; Chan H; Chan IT; Cheeti S; Cohen F; Deshayes K; Doerner K; Eckhardt SG; Elliott LO; Feng B; Franklin MC; Reisner SF; Gazzard L; Halladay J; Hymowitz SG; La H; LoRusso P; Maurer B; Murray L; Plise E; Quan C; Stephan JP; Young SG; Tom J; Tsui V; Um J; Varfolomeev E; Vucic D; Wagner AJ; Wallweber HJ; Wang L; Ware J; Wen Z; Wong H; Wong JM; Wong M; Wong S; Yu R; Zobel K; Fairbrother WJ
    J Med Chem; 2012 May; 55(9):4101-13. PubMed ID: 22413863
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.